Metabolites News and Research

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Penn State investigator receives $7.3 million grant for research on cellular protein

A faculty member in Penn State's College of Agricultural Sciences has received a $7.3 million grant for innovative research on a cellular protein that could be a target for enhancing immune function in response to a variety of diseases and environmental toxins.

15 Sep 2017

Probiotics may become new preventative or therapeutic strategy for IBD-related colon cancer

In an innovative approach to colorectal cancer (CRC) prevention and treatment, scientists are studying ways to replace missing metabolites in patients prone to gut inflammation and CRC.

14 Sep 2017

Researchers find unique genetic mutation in 74-year-old man with Parkinson's disease

Mutations in the human genome may be responsible for many diseases. In the case of Parkinson's disease (PD), five locations have been the subject of recent attention. Variants of one of these locations, ACMSD (aminocarboxymuconate semialdehyde decarboxylase), may be implicated in PD, but until now, no mutations in ACMSD have been found in any PD patients.

14 Sep 2017

Phthalate levels in expectant fathers influence sperm epigenetics, study suggests

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples' reproductive success via epigenetic modifications of sperm DNA.

12 Sep 2017

New device detects cancerous tissue during surgery within seconds

Researchers from the University of Texas at Austin have invented a pen-like, handheld device that can identify cancerous tissue in around 10 seconds during surgery, offering hope that procedures to remove cancer could be made quicker, more precise and safer.

7 Sep 2017

Mild pain killer blocks action of key protein required for hearing

A Rice University study has found that the aspirin-like drug diflunisal blocks the action of prestin, a key protein that is required for hearing.

5 Sep 2017

Fat may influence cancer development in diverse ways

Adipose tissue, or fat, may influence the development of cancer in diverse ways, depending on the type of fat and the location in the body.

1 Sep 2017

Study examines link between flame retardants and pregnancy outcomes in women undergoing fertility treatments

Women with higher urinary concentrations of a common type of flame retardant had reduced likelihood of clinical pregnancy and live birth than those with lower concentrations, according to researchers at Harvard T.H. Chan School of Public Health.

26 Aug 2017

Study reveals impact of flame retardants on reduced clinical pregnancy outcomes

A study conducted by a team of researchers at the Harvard T.H. Chan School of Public Health has found that for women with an increased concentration of a common type of flame retardant in their urine, there is a decreased possibility of clinical pregnancy as well as live birth when compared to those with a lower concentration.

25 Aug 2017

Gut bacteria in Hadza diet different from ours study finds

Probiotics are one of the fastest growing areas for research as well as one of the valued members in the food industry. These are healthy bacteria or friendly bacteria that are added to yogurts, drinks, and baby food in order to colonize out gut when we are taking antibiotics or are down with an intestinal infection.

24 Aug 2017

NASA’s Twins Study researchers explore the ground truth behind metabolites

You may think you're just an average Joe, but according to your metabolomics data your body is percolating some expressive information about your daily life.

24 Aug 2017

Scientists identify key compound that reduces severity of AMD in preclinical model

A compound of specific bioactive products from a major family of enzymes reduced the severity of age-related macular degeneration (AMD) in a preclinical model, according to a new study led by Massachusetts Eye and Ear researchers.

22 Aug 2017

Cortisol mediates communication between gut bacteria and brain metabolites, study suggests

Gut microbes have been in the news a lot lately. Recent studies show they can influence human health, behavior, and certain neurological disorders, such as autism.

21 Aug 2017

New biomarkers for early Lyme Disease identified

A team of researchers led by Colorado State University has developed a test to facilitate early diagnosis of Lyme Disease, which it is hoped will improved treatment outcomes. Until now, it was difficult to distinguish Lyme disease from similar, less severe tick-borne conditions.

18 Aug 2017

Study: Liver inflammation increases cholesterol levels in people with diabetes

Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases. This is the result of a study by scientists of Helmholtz Zentrum München, Technische Universität München and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital.

14 Aug 2017

Potential strategies to combat cardiovascular aging

Heart disease remains the leading cause of death in the U.S. and growing older is the greatest- and most inevitable- risk factor for it.

14 Aug 2017

Newly discovered biomarker linked to rare metabolic disorders may facilitate better diagnosis

A newly discovered biomarker associated with a rare metabolic disorder may facilitate better diagnosis and identification of new drugs for clinical trials for the disease, according to researchers in the Perelman School of Medicine at the University of Pennsylvania.

7 Aug 2017