Metformin News and Research

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Metformin is the active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body’s use of the glucose. Metformin is a type of antidiabetic agent.

Drug routines of children with type 1 diabetes are disrupted during holidays

Children with type 1 diabetes find it difficult to adhere to their drug routines during school holidays and weekends.

23 May 2019

Discovery could change the way fibromyalgia and chronic pain are treated

Researchers led by a team from The University of Texas Medical Branch at Galveston were able to dramatically reduce the pain of fibromyalgia patients with medication that targeted insulin resistance.

7 May 2019

Study results of a potential drug to treat Type 2 diabetes in children announced

Results of a recently completed clinical trial of a potential drug to treat Type 2 diabetes in children were announced Sunday [April 28] at the Pediatric Academic Societies 2019 meeting in Baltimore, Md. The New England Journal of Medicine also published the findings.

29 Apr 2019

New review on relationship between COPD and Type 2 diabetes

Chronic obstructive pulmonary disease is characterized by a chronic airflow obstruction that is associated with severe global mortality and morbidity.

23 Apr 2019

Diabetic drug shows potential to be repurposed as heart disease treatment for non-diabetic patients

The commonly used diabetes drug metformin could reverse the harmful thickening of heart muscle that leads to cardiovascular disease, according to a study at the University of Dundee.

17 Apr 2019

Common drug may lead to obesity in offspring

Metformin,a common drug used to treat type 2 diabetes, is often used during pregnancy where the mother suffersfrom polycystic ovary syndrome.

27 Mar 2019

Medication could mitigate side effects of chemotherapy for breast cancer patients

Researchers at the Stanford University School of Medicine have demonstrated a method of forecasting which breast cancer patients will suffer heart problems from a commonly used chemotherapy drug.

14 Mar 2019

Medical treatment for gestational diabetes could prevent long-term complications in children

Researchers at Cardiff University have found that women taking metformin and/or insulin during gestational diabetes could reduce the risk of long-term complications for their child.

11 Mar 2019

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous interventions, including diet changes and metformin.

8 Mar 2019

Patients experiment with prescription drugs to fight aging

Dr. Alan Green's patients travel from around the country to his tiny practice in Queens, N.Y., lured by the prospect of longer lives.

6 Mar 2019

Study to generate evidence on impact of pharmaceutical industry-led medicines access program

Study of Novartis Access program in Kenya demonstrates it is possible to evaluate major pharmaceutical companies' access programs using robust, 'gold standard' methods.

6 Mar 2019

Drug cocktail may help combat breast cancer

MYC, a gene with high cancer-initiating potential, is overexpressed in over 40% of breast cancers. While MYC programs breast cancer cells to build more macromolecules (anabolic metabolism) it also creates a metabolic vulnerability by making them more sensitive to a type of cell death known as apoptosis.

6 Feb 2019

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018

$Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction$

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction, a condition that is predicted to affect over 8% of people ages 65 or older by the year 2020.

19 Dec 2018

Researchers aim to improve cognition, reverse weight gain in schizophrenia

Aerobic exercise can improve the size and function of the brain, and now investigators want to know if it can also improve cognitive function in patients with schizophrenia who struggle with memory and attention problems.

19 Dec 2018

Gut bacteria may modify effectiveness of anti-diabetes drugs

Why do orally-administered drugs for diabetes work for some people but not others? According to researchers at Wake Forest School of Medicine, bacteria that make up the gut microbiome may be the culprit.

11 Dec 2018

Drug repositioning strategy identifies potential new treatments for epilepsy

Drug repositioning-- taking known drugs and identifying new applications for them--is an attractive concept for speeding up the process of bringing drugs to human testing for unmet medical needs.

11 Dec 2018

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth - this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

11 Dec 2018

Study: Some people with Type 2 diabetes may be testing their blood sugar more often than needed

For people with Type 2 diabetes, the task of testing their blood sugar with a fingertip prick and a drop of blood on a special strip of paper becomes part of everyday life.

11 Dec 2018

New research supports the need for obesity intervention before pregnancy

New research from the University of Adelaide's Robinson Research Institute supports the need for dietary and lifestyle interventions before overweight and obese women become pregnant.

6 Dec 2018

Metformin News and Research

Further Reading

Drug routines of children with type 1 diabetes are disrupted during holidays

Discovery could change the way fibromyalgia and chronic pain are treated

Study results of a potential drug to treat Type 2 diabetes in children announced

New review on relationship between COPD and Type 2 diabetes

Diabetic drug shows potential to be repurposed as heart disease treatment for non-diabetic patients

Common drug may lead to obesity in offspring

Medication could mitigate side effects of chemotherapy for breast cancer patients

Medical treatment for gestational diabetes could prevent long-term complications in children

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

Patients experiment with prescription drugs to fight aging

Study to generate evidence on impact of pharmaceutical industry-led medicines access program

Drug cocktail may help combat breast cancer

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Researchers aim to improve cognition, reverse weight gain in schizophrenia

Gut bacteria may modify effectiveness of anti-diabetes drugs

Drug repositioning strategy identifies potential new treatments for epilepsy

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

Study: Some people with Type 2 diabetes may be testing their blood sugar more often than needed

New research supports the need for obesity intervention before pregnancy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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