Methadone News and Research

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Buprenorphine is more effective than clonidine at helping people withdraw from opioids

It probably has similar effect as methadone, but withdrawal symptoms may resolve more quickly with buprenorphine.

18 Apr 2006

Study supports a flexible approach to methadone dosing

Methadone has been used for more than 30 years as a treatment for heroin addicts. Doctors have all along struggled to find the best doses to help patients overcome their heroin cravings without getting them used to higher levels of methadone (itself an dependence-forming substance) than necessary.

7 Feb 2006

Morphine withdrawal enhances hepatitis C virus (HCV) replicon expression

Researchers at the University of Pennsylvania have demonstrated that morphine withdrawal complicates hepatitis C by suppressing IFN-alpha-mediated immunity and enhancing virus replication.

30 Oct 2005

People living in predominantly minority areas face significant barriers to accessing pain medication

Chronic pain is a condition that affects one in five Americans without regard for their race or finances. But a new study finds that minorities and people with low incomes have less access than high-income white people to the medications that will help them endure their pain.

10 Oct 2005

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention, according to a study in the October issue of Archives of General Psychiatry.

4 Oct 2005

First direct evidence that endorphins play a role in the phenomenon known as the placebo effect

Just thinking that a medicine will relieve pain is enough to prompt the brain to release its own natural painkillers, and soothe painful sensations, a new University of Michigan study finds.

23 Aug 2005

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Opiates appear to better "ameliorate the withdrawal, facilitate feeding and potentially reduce the likelihood of seizures," according to two new systematic reviews done by David Osborn, a neonatologist at the Royal Prince Alfred Hospital in Sydney, Australia, and colleagues.

26 Jul 2005

Drug abusers are increasingly turning to a slow-release form of drug fentanyl

Drug abusers are increasingly turning to a slow-release form of a powerful painkiller for a quick and dangerous high, University of Florida researchers warn. The trend is raising alarm as the number of people dying from an overdose of the drug fentanyl, an opioid 100 times more potent than morphine, rises.

6 Jul 2005

Office-based buprenorphine treatment for drug abuse shows promise

Patients who receive buprenorphine treatment for opioid addiction in an office-based setting are more likely than those receiving methadone treatment to be young men, new to drug use, and with no history of methadone treatment, Yale School of Medicine researchers report in a study published in Drug and Alcohol Dependence.

28 Jun 2005

Buprenorphine treatment for opioid addiction shows promise

16 Jun 2005

Combining morphine with small doses of methadone could increase the effectiveness of morphine for the treatment of chronic pain

Although morphine is well known as a highly effective analgesic, its clinical utility is severely limited by the development of drug tolerance, the requirement for increasing doses to maintain analgesic effect, and the development of physical dependence.

6 Jun 2005

Dutch team shows cost effectiveness of heroin prescriptions

Researchers at the University of Amsterdam say there are strong reasons to support the practice of prescribing heroin to drug misusers.

6 Jun 2005

Prescribing methadone plus heroin to chronic, treatment resistant addicts is less costly than methadone alone

Prescribing methadone plus heroin to chronic, treatment resistant addicts is less costly than methadone alone because it reduces criminal behaviour, finds a study in this week's BMJ.

3 Jun 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, UCSF medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

23 May 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, University of California, San Francisco (UCSF) medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

20 May 2005

Methadone News and Research

Buprenorphine is more effective than clonidine at helping people withdraw from opioids

Study supports a flexible approach to methadone dosing

Morphine withdrawal enhances hepatitis C virus (HCV) replicon expression

People living in predominantly minority areas face significant barriers to accessing pain medication

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

First direct evidence that endorphins play a role in the phenomenon known as the placebo effect

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Drug abusers are increasingly turning to a slow-release form of drug fentanyl

Office-based buprenorphine treatment for drug abuse shows promise

Buprenorphine treatment for opioid addiction shows promise

Combining morphine with small doses of methadone could increase the effectiveness of morphine for the treatment of chronic pain

Dutch team shows cost effectiveness of heroin prescriptions

Prescribing methadone plus heroin to chronic, treatment resistant addicts is less costly than methadone alone

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Researchers are changing the face of drug addiction treatment

Moldova making progress in fight against HIV/AIDS and tuberculosis

Biotoxin from puffer fish may provide treatment for opioid withdrawal

Using antidepressant medication to treat people with depression and alcohol or drug abuse is beneficial

Call for special help for young people who inject drugs

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