MicroRNA News and Research

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In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression.
New platform can detect microRNA-205 with high sensitivity, excellent selectivity

New platform can detect microRNA-205 with high sensitivity, excellent selectivity

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Study uncovers mechanisms by which microRNAs drive atherogenesis in a cell-type-specific manner

Synthetic microRNA can serve as a novel therapeutic agent for treating human cancer

Synthetic microRNA can serve as a novel therapeutic agent for treating human cancer

Researchers develop proof-of-concept treatment for blood disorders

Researchers develop proof-of-concept treatment for blood disorders

Newly identified small molecule can be used to rejuvenate the brain, counteract memory loss

Newly identified small molecule can be used to rejuvenate the brain, counteract memory loss

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

New study launched to more accurately diagnose early hepatocellular carcinoma

New study launched to more accurately diagnose early hepatocellular carcinoma

Study reveals a hidden role of circulating microRNA as a driver of SARS-CoV-2 infection

Study reveals a hidden role of circulating microRNA as a driver of SARS-CoV-2 infection

New approach to scale up genome editing in tiny worms

New approach to scale up genome editing in tiny worms

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Microrna-29 molecule controls brain maturation in mammals

Microrna-29 molecule controls brain maturation in mammals

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

UNC scientists identify a molecule as powerful controller of brain maturation in mammals

New biomarker of glucocorticoid action could help clinicians to tailor treatments

New biomarker of glucocorticoid action could help clinicians to tailor treatments

Devastating liver disease itching turns out to have a surprising cause

Devastating liver disease itching turns out to have a surprising cause

New RNA-sequencing method can help detect numerous modified small RNAs

New RNA-sequencing method can help detect numerous modified small RNAs

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies

UVA researcher developing innovative gene therapy to help children with Rett syndrome

UVA researcher developing innovative gene therapy to help children with Rett syndrome

Researchers identify a possible cause of functional neurological disorder

Researchers identify a possible cause of functional neurological disorder

Otago researchers find how to treat heart disease in type-2 diabetics

Otago researchers find how to treat heart disease in type-2 diabetics