A Microbicide is any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). Also called germicide.
AIDS activists in South Africa are calling for clinical trials of a microbicide gel designed to help women protect themselves against HIV to be restarted.
In what appears to be a disappointing outcome, trials of a new gel designed for women to protect themselves from the AIDS virus were stopped this week when researchers found that women using it became infected at a higher rate than women not using it.
A Phase III study of the candidate microbicide cellulose sulfate to prevent HIV transmission in women has been stopped prematurely because of a higher number of HIV infections in the active compared with the placebo group.
Cellegy Pharmaceuticals on Monday announced that it has ended phase Phase III clinical trials in Nigeria on its microbicide Savvy, the Philadelphia Inquirer reports (Loyd, Philadelphia Inquirer, 8/29).
Dr Anders Nordstrom, Acting Director-General of the World Health Organization told delegates at the XVIth International AIDS Conference that "drastic measures" were required to ensure there are enough health workers available to deliver universal access to HIV/AIDS prevention, treatment, care and support by 2010.
Microsoft founder Bill Gates says all the money in the world will not conquer HIV/AIDS unless more progress is made in preventing new infections. Gates says women and other high-risk groups must be given the ability to protect themselves.
Bill and Melinda Gates has called upon world leaders to "put the power to prevent HIV in the hands of women" by accelerating the search for microbicides and other new HIV prevention tools.
Researchers have come up with a novel delivery system for anti-AIDS drugs: milk-curdling bacteria used to make yogurt and cheese.
Giant American drug companies Merck and Bristol-Myers Squibb, have signed agreements to develop a treatment called a microbicide, a gel or a cream that women can use to protect themselves from AIDS.
Research with female monkeys at the Tulane National Primate Research Center has for the first time shown that three different anti-viral agents in a vaginal gel protect the animals against an HIV-like virus.
The silicone vaginal ring steadily releases aciclovir: a treatment for genital herpes. It is known that women with genital herpes are at increased risk of HIV infection because the genital blisters caused by the infection increase the transmissibility of sexually acquired HIV.
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced an agreement with the International Partnership for Microbicides (IPM) to share information and expertise in an effort to develop vaginal microbicides
Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina.
Melbourne-based nanotechnology company Starpharma will lead a consortium to develop a second generation microbicide for the prevention of infection by HIV and other sexually transmitted diseases (STDs).
Researchers at the Biodesign Institute at ASU have been tapped to lead development of plant-derived topical medications that would prevent HIV/AIDS and other sexually-transmitted diseases.
International Partnership for Microbicides (IPM) today announced that it has reached a farsighted agreement with Tibotec Pharmaceuticals Ltd, a subsidiary of Johnson & Johnson. The aim is to develop the promising compound TMC120 as a safe and effective microbicide to help protect women from infection with HIV. This agreement marks the first collaboration in the microbicide field between a major healthcare company and a public-private partnership such as IPM.