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Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

The National Institute of Allergy and Infectious Diseases awarded an up to $16 million contract to Tulane University to bring to phase one clinical trial a nasal spray vaccine university researchers invented to thwart antibiotic-resistant Klebsiella pneumoniae, a leading cause of pneumonia.

24 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

Candida auris infection without epidemiologic links to a prior outbreak

The Centers for Disease Control and Prevention (CDC) has classified Candida auris (C. auris) as an urgent public threat due to its role in elevating mortality, its ability to persist in hospital environments, and the high possibility of developing pan-drug resistance.

23 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Inhibition of cell wall formation arrests staphylococcal cell division

We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics.

23 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2.

22 Mar 2023

Co-infection with MRSA ‘superbug’ could make COVID-19 outcomes even more deadly

Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection – with Staphylococcus aureus, also known as Staph A., being the most common organism responsible for co-existing infections with SARS-CoV-2.

21 Mar 2023

Vaginal sex can shape the composition of urethral microbiome in healthy men

Contrary to common beliefs, your urine is not germ free. In fact, a new study shows that the urethra of healthy men is teeming with microbial life and that a specific activity-;vaginal sex-;can shape its composition.

21 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

20 Mar 2023

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

The magnitude and quality of a key immune cell's response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found.

20 Mar 2023

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

COVID-19 has caused significant global panic after its rapid emergence more than 3 years ago. Although we now have highly effective vaccines against the SARS-CoV-2 virus, which causes COVID-19, scientists continue to study emerging SARS-CoV-2 variants in order to safeguard public health and devise global preventive strategies against emerging variants.

20 Mar 2023

Microbiology News and Research

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

High-resolution mass spectrometric rapid identification of Candida auris

Candida auris infection without epidemiologic links to a prior outbreak

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Inhibition of cell wall formation arrests staphylococcal cell division

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

Co-infection with MRSA ‘superbug’ could make COVID-19 outcomes even more deadly

Vaginal sex can shape the composition of urethral microbiome in healthy men

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

Usefulness of dried blood spot samples for monitoring HCV infection in people who inject drugs

Decreased viral infection severity in females may be due to extra copy of X chromosome-linked gene

Real-world data on the effectiveness of Sotrovimab as a prophylactic against COVID-19

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Research identifies western diet-induced microbial and metabolic contributors to liver disease

Host immune system forms small lesions in the intestines in response to bacterial infection

Wayne State team discovers a simple technology to detect active TB infection antibodies

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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