Microcephaly News and Research

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Measuring head circumference (also known as occipito-frontal circumference) is a significant part of the proper evaluation of a child’s growth and development, as it represents a direct indication of head growth. Therefore deviations from normal head growth may reveal certain congenital or acquired problem.

Research reveals how Zika virus arrests fetal brain development in pigtail macaque

For the first time, abnormal brain development following a Zika infection during pregnancy has been documented experimentally in the offspring of a non-human primate.

12 Sep 2016

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.

9 Sep 2016

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

As health departments around the U.S. boost efforts to combat Zika, scientists are working on new ways to kill the mosquitoes that carry the virus. One approach involves understanding the molecular mechanisms that keep the bugs alive so we can then undermine them.

9 Sep 2016

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

Scientists have revealed molecular differences between how the African and Asian strains of Zika virus infect neural progenitor cells.

1 Sep 2016

New research shows female mosquitoes can pass Zika virus to their offsprings

New research from The University of Texas Medical Branch in Galveston has shown that female Aedes aegypti mosquitoes can pass the Zika virus to their eggs and offspring.

30 Aug 2016

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells.

29 Aug 2016

Spotlight Innovation, FSU collaborate to support development of novel therapies for Zika virus infection

Spotlight Innovation Inc. has entered into a Sponsored Research Agreement with Florida State University to support research directed by FSU Prof. Hengli Tang aimed at developing safe and effective drugs to treat patients infected with Zika virus (ZIKV).

27 Aug 2016

Biostatisticians project nearly 400 non-travel Zika cases in Florida by end of summer

Nearly 400 non travel-related Zika infections will occur in Florida before the end of the summer, according to new projections by biostatisticians at the University of Florida and other institutions.

27 Aug 2016

Scientists report new neurological complication from Zika virus infection

Dr. John England, Professor and Chair of Neurology at LSU Health New Orleans School of Medicine, and colleagues in Honduras and Venezuela have reported a new neurological complication of infection with the Zika virus.

26 Aug 2016

Researchers link sensory polyneuropathy with acute Zika virus infection

A group of researchers from Honduras, Venezuela and the USA has described the first case of sensory polyneuropathy associated with acute Zika virus infection.

26 Aug 2016

New report documents fetal brain abnormalities linked to congenital Zika infection

In a special report released August 23 in the journal Radiology, a team of researchers including Deborah Levine, MD, Director of Obstetric & Gynecologic ultrasound at Beth Israel Deaconess Medical Center and professor of radiology at Harvard Medical School, documented the brain abnormalities associated with congenital Zika in 45 confirmed and presumed cases from northeastern Brazil.

26 Aug 2016

Malformations in the brains of fetuses caused by Zika virus go beyond microcephaly

A recent study published by Brazilian researchers from the D'Or Institute for Research and Education, Federal University of Rio de Janeiro, Institute for Research Professor Amorim Neto, alongside Tel Aviv University and the Boston Children's Hospital in the US, indicates that microcephaly, a very usual feature in cases of Zika virus gestational infection, is just one of several observed brain changes.

24 Aug 2016

New study may offer vital clues to understanding how Zika virus affects the developing brain

In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.

24 Aug 2016

Yale study provides insight into how Zika virus may be transmitted from pregnant mother to fetus

In a new study, Yale researchers demonstrate Zika virus infection of cells derived from human placentas. The research provides insight into how Zika virus may be transmitted from expectant mother to fetus, resulting in infection of the fetal brain.

18 Aug 2016

USC researchers discover two Zika proteins potentially responsible for microcephaly

USC researchers have tracked down two Zika proteins potentially responsible for thousands of microcephaly cases in Brazil and elsewhere — taking one small step toward preventing Zika-infected mothers from birthing babies with abnormally small heads.

11 Aug 2016

Experts propose new clinical guidelines for diagnosing FASD

A group of experts on fetal alcohol spectrum disorders, organized by the National Institute on Alcohol Abuse and Alcoholism, has produced proposed clinical guidelines for diagnosing FASD, which can result when a mother drinks during pregnancy.

11 Aug 2016

Scientists modeling new control mechanism to combat Zika-infecting mosquitoes

The images are heartbreaking: thousands of infants born with small, misshapen heads, the result of a rare neurological disorder, called microcephaly, which can cause a myriad of intellectual and developmental disabilities. The culprit? Zika, a mosquito-borne virus that has swept through many parts of South America and more recently surfaced in Florida.

8 Aug 2016

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors -- even as it changed the lives of the babies born with it during the pre-Zika era.

8 Aug 2016

UM SOM selected as study site for human safety trial of new Zika vaccine

As world leaders increasingly recognize the Zika virus as an international public health threat, the Center for Vaccine Development at the University of Maryland School of Medicine's Institute for Global Health has been chosen as one of three study sites in a human safety trial of a new Zika vaccine.

7 Aug 2016

Wiley's Zika page offers free access to published content to coincide with events in Brazil

Wiley has made available all of its published Zika content on one site http://www.wiley.com/go/zika to coincide with events in Brazil, a territory that has seen increased cases of Zika Virus recently.

5 Aug 2016

Microcephaly News and Research

Further Reading

Research reveals how Zika virus arrests fetal brain development in pigtail macaque

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

Researchers uncover molecular differences between African and Asian strain of Zika virus infections

New research shows female mosquitoes can pass Zika virus to their offsprings

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Spotlight Innovation, FSU collaborate to support development of novel therapies for Zika virus infection

Biostatisticians project nearly 400 non-travel Zika cases in Florida by end of summer

Scientists report new neurological complication from Zika virus infection

Researchers link sensory polyneuropathy with acute Zika virus infection

New report documents fetal brain abnormalities linked to congenital Zika infection

Malformations in the brains of fetuses caused by Zika virus go beyond microcephaly

New study may offer vital clues to understanding how Zika virus affects the developing brain

Yale study provides insight into how Zika virus may be transmitted from pregnant mother to fetus

USC researchers discover two Zika proteins potentially responsible for microcephaly

Experts propose new clinical guidelines for diagnosing FASD

Scientists modeling new control mechanism to combat Zika-infecting mosquitoes

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

UM SOM selected as study site for human safety trial of new Zika vaccine

Wiley's Zika page offers free access to published content to coincide with events in Brazil

Expanding research and clinical options for children with cancer

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