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Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

Low-dose radiation shows promise as treatment for brain injury and stroke

Traumatic brain injury (TBI) and ischemic stroke are major public health concerns and leading causes of death and disability worldwide.

27 Jan 2024

Scientists discover key brain cells affected by COVID-19

A recent Cell Stem Cell study investigated whether SARS-CoV-2 infection leads to dopaminergic neuron senescence.

22 Jan 2024

Blocking brain inflammation could slow, reverse ALS symptoms

In people with amyotrophic lateral sclerosis (ALS), changes in neurons appear to activate immune cells. Lowering the inflammation could reduce the symptoms of the disease, according to a study led by Chantelle Sephton, a professor at Université Laval's Faculty of Medicine.

10 Jan 2024

Infammasomes provide a therapeutic target against human diseases

The structure of inflammasomes and their role in diseases.

9 Jan 2024

New study shows intermittent fasting reduces obesity-related brain inflammation and cognitive decline

The long-term beneficial effects of intermittent fasting (IF).

5 Jan 2024

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders.

4 Jan 2024

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester find that microglia-;the brain's immune cells-;can trigger cognitive deficits after radiation exposure and may be a key target for preventing these symptoms.

3 Jan 2024

Microglia found to play a key role in regulating the body's response to anesthesia

Though it may be a surprise to the millions of people who undergo general anesthesia every year for medical procedures, the biological mechanism for how different anesthetics block consciousness is still not fully understood.

22 Dec 2023

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce meaningful therapeutic effects for people with Alzheimer's disease.

20 Dec 2023

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Transcranial photobiomodulation (tPBM) treatment affected insulin therapy on microglial function.

12 Dec 2023

Colombian family's Alzheimer's anomaly offers insights into disease pathogenesis and prevention

Alzheimer's disease has plagued one large Colombian family for generations, striking down half of its members in the prime of life.

11 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

Study provides a better understanding of how the brain responds to injuries

A new study published in Proceedings of the National Academy of Sciences Nexus provides a better understanding of how the brain responds to injuries.

11 Dec 2023

Targeting Alzheimer's with cell-specific genetics

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

5 Dec 2023

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

A study by Brigham investigators revealed how genetic changes in certain types of brain cells may contribute to the inflammatory response seen in Alzheimer's disease.

28 Nov 2023

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins.

28 Nov 2023

Immune receptor protein linked to healthy aging and lifespan in mice

Life expectancy and healthy aging in mice can be determined by a protein present in some cells of the immune system, according to a study published in the journal Cell Reports.

28 Nov 2023

Researchers take step toward developing cell therapy treatment for MS

An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.

27 Nov 2023

Reducing cholesterol esters protects the brain against Alzheimer's-like damage

In Alzheimer's disease and related dementias, cognitive decline is driven by the overaccumulation of a normal brain protein known as tau.

22 Nov 2023

Microglia News and Research

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Low-dose radiation shows promise as treatment for brain injury and stroke

Scientists discover key brain cells affected by COVID-19

Blocking brain inflammation could slow, reverse ALS symptoms

Infammasomes provide a therapeutic target against human diseases

New study shows intermittent fasting reduces obesity-related brain inflammation and cognitive decline

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

Microglia found to play a key role in regulating the body's response to anesthesia

Gamma stimulation may improve memory and cognition in people with Alzheimer's disease

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Colombian family's Alzheimer's anomaly offers insights into disease pathogenesis and prevention

MIT scientists develop nanoparticles to reduce inflammation in the brain

Study provides a better understanding of how the brain responds to injuries

Targeting Alzheimer's with cell-specific genetics

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Immune receptor protein linked to healthy aging and lifespan in mice

Researchers take step toward developing cell therapy treatment for MS

Reducing cholesterol esters protects the brain against Alzheimer's-like damage

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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