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New tool allows researchers to perform genetic screens of cell-cell interactions

Inflammatory neurological diseases, such as multiple sclerosis (MS), can arise when cell-to-cell communication between cells in the central nervous system (CNS) goes awry.

13 Mar 2023

Microglia partner with T cells to cause neurodegeneration, study shows

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

8 Mar 2023

Scientists unearth a potential new target for treating age-related neurological diseases

Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on aging processes in the brain.

8 Mar 2023

Study may provide a new target for treatment of Alzheimer's disease

Reducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer's disease in a mouse model, according to a new study publishing March 7th in the open access journal PLOS Biology by Rui Zhang of Air Force Medical University in Xian, Shaanxi, China.

7 Mar 2023

Analysis provides new insights into complex effects of Alzheimer’s disease on the retina

Cedars-Sinai investigators have produced the most extensive analysis to date of changes in the retina-;a layer of tissue at the back of the eye where visual information originates-;and how those retinal changes correspond to brain and cognitive changes in Alzheimer's disease patients.

3 Mar 2023

Microglia may be the culprit behind concentration and memory problems after chemotherapy

Immune cells that keep the brain free of debris but also contribute to inflammation are the likely culprits behind the concentration and memory problems that sometimes follow one type of chemotherapy, a new study in mice suggests.

28 Feb 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Microglia News and Research

New tool allows researchers to perform genetic screens of cell-cell interactions

Microglia partner with T cells to cause neurodegeneration, study shows

Scientists unearth a potential new target for treating age-related neurological diseases

Study may provide a new target for treatment of Alzheimer's disease

Analysis provides new insights into complex effects of Alzheimer’s disease on the retina

Microglia may be the culprit behind concentration and memory problems after chemotherapy

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

What do gut microbiota have to do with Alzheimer's and dementia?

Analysis of rebound virus suggests two separate reservoirs of latent HIV in patients

New discovery about microglia heralds myriad possibilities for treating neurodegenerative diseases

Sex-specific patterns of cytokine activation in the hippocampus post-immunological challenge

Study reveals sex differences in response to drugs targeting tauopathies

How does the brain change with age?

Imaris launches 10.0, an AI-powered software for fast and accurate detection of neurons, microglia and blood vessels

Breached dolphin's brains show neuropathology similar to Alzheimer's

First cell-type specific multiomic study of the HIV brain

Study highlights the importance of the gut microbiota during early neurodevelopment

New clue may explain why women are at greater risk for Alzheimer's disease

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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