Microorganism News and Research

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Simple organism can produce 10 trillion varieties of a single protein

A team led by University of California, San Diego biochemists has discovered the mechanism by which a simple organism can produce 10 trillion varieties of a single protein, a finding that provides a new tool to develop novel drugs.

21 Sep 2005

New way to "image" the internal chemistry of bacteria

As part of the search for better ways to track and clean up soil contaminants, scientists at the U.S. Department of Energy's Brookhaven National Laboratory and Stony Brook University have developed a new way to "image" the internal chemistry of bacteria.

29 Aug 2005

New program will help fill a drug-discovery void as pharmaceutical companies have largely abandoned natural products research

The natural world has been medicine's most effective arsenal, providing life-saving antibiotics and our most potent anti-cancer drugs.

20 Jul 2005

Scientists sequence the genomes of three species of parasites responsible for causing diseases that kill or cripple millions

Howard Hughes Medical Institute (HHMI) scientists who participated in the project say the sequencing of the genomes of the parasitic protozoa that cause Chagas disease, African sleeping sickness, and leishmaniasis, could significantly impact world health. Some of the genes discovered may prove to be good drug and vaccine targets.

17 Jul 2005

HIF-1alpha expression regulates the bactericidal capacity of phagocytes

When microorganisms invade the body, immune mechanisms kick in to fight them off. The infected tissues typically show depleted oxygen levels, and a protein called HIF-1 alpha regulates this. Interestingly, the cells responsible for destroying the foreign pathogens are effective in this low-oxygen environment.

6 Jul 2005

Routine immunisation against meningitis and pneumonia should be introduced for children in developing countries

Routine immunisation against a bacterial microorganism that can cause meningitis and pneumonia should be introduced for children in developing countries, suggests a report published in this week’s issue of The Lancet.

28 Jun 2005

Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine

Mice given a relatively new cancer drug can survive an otherwise lethal dose of vaccinia virus, a relative of smallpox virus, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID).

27 Jun 2005

Scientists solve structure of a critical innate immune system protein

Scientists at The Scripps Research Institute have solved the structure of a crucial human immune system molecule called TLR3, an acronym for Toll-like receptor three. In an upcoming issue of the journal Science, the protein is described as a large horseshoe-shaped coil composed of 23 leucine-rich repeats (LRRs).

27 Jun 2005

PNNL ScalaBLAST may be used to process complex genomic sequences

A new computational tool developed at the Department of Energy's Pacific Northwest National Laboratory is speeding up our understanding of the machinery of life - bringing us one step closer to curing diseases, finding safer ways to clean the environment and protecting the country against biological threats.

21 Jun 2005

Textiles with permanent antibacterial properties

Antimicrobial agents are not new to the marketplace. Our stores are filled with antibacterial soaps and gels, and in a post-9/11 world, wearable protection from biological agents is in increasing demand. So far, antimicrobial textile production has used coatings that can wash away over time, reducing the useful life of protective clothing.

21 Jun 2005

New process removes allergy potential from peanut products

Scientists say a special fermentation process may significantly reduce the potential for allergic reaction to peanut products.

6 Jun 2005

World first air purification technology for H5N1 Avian Influenza

Sharp Corporation has demonstrated that Plasmacluster Ions reduce activity of the highly fatal and highly pathogenic airborne H5N1 avian influenza ("bird flu") virus by 99%.

6 Jun 2005

Artificial cobweb proteins for medicine

A unique material based on cobweb proteins is being created by Russian researchers of the State Research Center of Russian Federation GosNIIgentics, Scientific Research Center “Coal-Chemical Fiber”, State Research Center of Applied Microbiology in cooperation with their colleagues from Michigan University with support form the International Science and Technology Center (ISTC) (project 1033.2).

30 May 2005

Alcohol consumption increases movement of S. pneumoniae toward the lungs

Streptococcus pneumoniae is a bacterium that can infect the upper respiratory tract and cause pneumonia, as well as infections in other parts of the body such as the bloodstream (bacteremia), lining of the brain and spinal cord (meningitis), bones (osteomyelitis), joints (arthritis), ears (otitis media) and sinuses (sinusitis).

15 May 2005

As science gets wiser, so do the bugs

As science gets wiser, so do the bugs. The rates of drug-resistant bacteria infecting patients in the community and in the hospital have been increasing steadily in recent years, according to two new studies in the June 15 issue of Clinical Infectious Diseases.

9 May 2005

Researchers develop new method for facile identification of proteins in bacterial cells

Researchers at the Johns Hopkins Bloomberg School of Public Health have developed a new method for identifying specific proteins in whole cell extracts of microorganisms using traditional peptide mass fingerprinting (PMF).

4 May 2005

Aging population correlates with a switch from acute infectious diseases to chronic diseases as the major cause of morbidity and mortality

Some diseases like ulcers and certain types of cancer, once thought to be primarily related to lifestyle factors, are now known to be caused by microorganisms, and many more syndromes, including some psychiatric conditions, may have a connection to infection, according to a report released today by the American Academy of Microbiology.

22 Apr 2005

No strong evidence linking blood mercury levels with worse neurobehavioral performance in older adults

In a study of older adults, researchers did not find a definitive association between blood mercury levels, which can become elevated with fish consumption, and adverse neurobehavioral effects, according to a study in the April 20 issue of JAMA.

19 Apr 2005

Natural killer cells could lead to new Hepatitis treatments

Researchers have discovered that natural killer T (NKT) cells, the immune system's sentinels, patrol the labyrinthine blood vessels of the liver for invaders or signs of tissue damage and demonstrate a dogged behavior not seen before in other T cells.

4 Apr 2005

Blue light kills gum disease

Scientists at The Forsyth Institute have found that blue light can be used to selectively suppress certain bacteria commonly associated with destructive gum disease.

3 Apr 2005