Mitochondria News and Research

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Exeter scientists discover how two cell organelles interact at molecular level

Scientists have made a breakthrough in understanding how different compartments (or organelles) of human cells interact.

20 Jan 2017

NYU Langone scientists discover mechanism behind many disease-related genetic deletions

Scientists at NYU Langone Medical Center have discovered the mechanisms behind a genetic change known to cause a set of related diseases.

20 Jan 2017

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy-induced neuropathy and HIV.

18 Jan 2017

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system's ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.

12 Jan 2017

Duke researchers use cancer-seeking salmonella to treat glioblastoma

Biomedical engineers at Duke University have recruited an unlikely ally in the fight against the deadliest form of brain cancer -- a strain of salmonella that usually causes food poisoning.

11 Jan 2017

Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease

People with certain forms of early-onset Parkinson's disease may benefit from boosting the amount of niacin in their diet, according to new research from the University of Leicester.

11 Jan 2017

Cell powerhouses may be good therapeutic target for brain injury

Cell powerhouses are typically long and lean, but with brain injury such as stroke or trauma, they can quickly become bloated and dysfunctional, say scientists who documented the phenomena in real time for the first time in a living brain.

10 Jan 2017

Researchers reveal how inflammatory responses block fat cell conversion

Scientists at the University of Bonn have shown in mice that excess pounds can simply be melted away by converting unwanted white fat cells into energy-consuming brown slimming cells.

3 Jan 2017

Novel murine model helps shed light on mechanisms involved in reversible infantile liver failure

Reversible infantile liver failure (RILF) is a heritable mitochondrial condition that causes severe liver dysfunction in infancy, but those who survive the acute stage typically recover and have no further problems.

27 Dec 2016

Combination of diabetes and hypertension drugs can effectively treat cancer

A combination of a diabetes medication and an antihypertensive drug can effectively combat cancer cells.

27 Dec 2016

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

New study reveals IRBIT's role in facilitating apoptosis

Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur properly.

21 Dec 2016

CNIC scientists reveal fundamental role of hypoxia response in correct formation of the heart

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have demonstrated the fundamental role of the hypoxia response in the correct formation of the heart ventricles.

19 Dec 2016

Scientists identify novel protein pathway across cancer types that fuels tumor progression

Scientists at The Wistar Institute have identified a novel protein pathway across several types of cancer that controls how tumor cells acquire the energy necessary for movement, invasion and metastasis.

19 Dec 2016

UK to officially authorise clinical use of ground-breaking ‘three-person baby IVF’

The United Kingdom will likely this week become the first country to officially authorise clinical use of ground-breaking mitochondrial donation IVF to enable healthy babies to be born to women carrying deadly mitochondrial disease, which starves major organs of energy.

16 Dec 2016

UNIST study could open up new avenues of research in cancer treatment

The new study, by researchers from UNIST demonstrates a more holistic light-based treatment to nuke cancer cells instead of surgery. The results, reported in the September issue of the Journal of the American Chemical Society, could open up new avenues of research in cancer treatment.

14 Dec 2016

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Discovered in the 1970s, tumor suppressors are among the most important proteins in the body.

8 Dec 2016

Signaling pathway in fat cells may provide key to better treatments for obesity, Penn research finds

A signaling pathway in fat cells may one day provide the key to better treatments for obesity, according to new research by scientists in the Perelman School of Medicine at the University of Pennsylvania.

6 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

Biomedical scientist develops new way to create micro muscles for testing muscle efficiency

A biomedical research scientist is taking the lead in the creation of muscle cells and micro muscles to test muscle efficiency in the laboratory - and he is able to carry out this new and innovative work thanks to the support he has received to get him back into science after a career break.

30 Nov 2016