Mitochondria News and Research

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TUM scientists uncover novel mechanisms of action for skin disease medication

Imiquimod is a medication successfully used in the treatment of skin diseases. In addition to its known mechanism of action, it also triggers other processes in the body.

20 Oct 2016

Study unravels how caloric restriction provides beneficial effects to the brain

Studies of different animal species suggest a link between eating less and living longer, but the molecular mechanisms by which caloric restriction affords protection against disease and extends longevity are not well understood.

19 Oct 2016

Researchers come together to discuss potential impact of exercise at all stages of life

Get more exercise. The often-repeated health recommendation is usually prescribed to lose weight or build muscle, but the many health effects of exercise reach far beyond weight and body composition.

19 Oct 2016

Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

High cholesterol might harm more than our cardiovascular systems. New research using animal models, published online in The FASEB Journal, suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.

17 Oct 2016

UPV participates in Lumiblast project to develop novel treatments for hard-to-treat brain tumours

The Polytechnic University of Valencia is taking part in Lumiblast, a European project to develop an innovative approach to hard-to-treat brain tumours like glioblastomas.

14 Oct 2016

Substance NAD+ can extend life and postpone onset of aging processes

The coenzyme NAD+ plays a main role in aging processes. In mice and roundworm adding the substance can both extend life and postpone the onset of aging processes.

14 Oct 2016

U of A researchers to study origin of Leigh's disease

Researchers at the University of Arkansas and their collaborators will use a $1.4 million grant from the U.S. Department of Defense to study the origin of Leigh's disease, a rare and incurable disease that affects the central nervous system.

13 Oct 2016

Novel microwave-induced photodynamic therapy could target deeply situated tumors

Physicists at The University of Texas at Arlington have shown that using microwaves to activate photosensitive nanoparticles produces tissue-heating effects that ultimately lead to cell death within solid tumors.

12 Oct 2016

New study shows ways to expand therapeutic potential of hMSCs

Stem cells hold great promise for transforming medical care related to a diverse range of conditions, but the cells often lose some of their therapeutic potential when scientists try to grow and expand them in the laboratory.

12 Oct 2016

Johns Hopkins researchers identify protein that triggers brain cell death from strokes and injuries

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer's.

7 Oct 2016

ISU research may suggest new cure for Parkinson's disease

Recently published research from Iowa State University may hint at a new treatment for Parkinson's disease.

6 Oct 2016

Gut may play key role in preventing Parkinson's disease

Your gut may play a pivotal role in preventing the onset of Parkinson's disease. And the reason may be its knack for sleuthing.

5 Oct 2016

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found, in animal models of human breast cancer, that inhibiting a single protein restores sensitivity to tamoxifen, a commonly used drug for treatment of some breast cancers.

3 Oct 2016

Breakthrough research opens door to potential new therapies for inflammatory diseases

Scientists have made a major breakthrough in understanding the workings of the cellular machinery involved in a host of inflammatory diseases.

24 Sep 2016

Mitochondrial alternative oxidase from sea-squirt shows potential to fight against sepsis

Mitochondrial alternative oxidase from a sea-squirt works as a safety valve for stressed mitochondria. This property enables it to stop the runaway inflammatory process that leads to multiple organ failure and eventual death in bacterial sepsis.

23 Sep 2016

Research findings point to potential new targeted therapy for SMA

For the first time, scientists found that in spinal muscular atrophy (SMA), the affected nerve cells that control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the cell.

15 Sep 2016

New study identifies potential therapeutic option for treatment of Huntington's disease

A new scientific study reveals one way to stop proteins from triggering an energy failure inside nerve cells during Huntington's disease. Huntington's disease is an inherited genetic disorder caused by mutations in the gene that encodes huntingtin protein.

14 Sep 2016