Mitochondria News and Research

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Researchers find promising new therapy for both pediatric and adult cancers

A study conducted at Nationwide Children's Hospital has found that a new chemotherapy is effective against both pediatric and adult cancers, and that it allows other chemotherapies to more readily reach their targets.

28 Jul 2016

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

Variations in a gene with multiple functions in neurons are present in approximately 3 percent of all cases of ALS in North American and European populations, both sporadic and familial, making it one of the most common genetic causes of the disease, according to a paper published in Nature Genetics.

26 Jul 2016

New wonder compound offers strong protection against harmful effects of UVA rays

A new wonder compound developed by University of Bath scientists in collaboration with King's College London offers unprecedented protection against the harmful effects of UVA radiation in sunlight, which include photo-ageing, cell damage and cancer.

20 Jul 2016

Study offers new hope for preventing chronic lung disease in premature infants

By triggering a process called autophagy -- in which cells literally engulf their own insides --researchers from Drexel University and Yale University were able to decrease lung injury in mice that were exposed to high concentrations of oxygen.

20 Jul 2016

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

In a study published this week in the Proceedings of the National Academy of Sciences, a University of Wisconsin-Madison research team pinpoints how immune abnormalities beneath the retina result in macular degeneration, a common condition that often causes blindness.

19 Jul 2016

UC Davis scientists show how cells control DNA synthesis in mitochondria

Aging, neurodegenerative disorders and metabolic disease are all linked to mitochondria, structures within our cells that generate chemical energy and maintain their own DNA. In a fundamental discovery with far-reaching implications, scientists at the University of California, Davis, now show how cells control DNA synthesis in mitochondria and couple it to mitochondrial division.

18 Jul 2016

Scientists explore ways to make fat cells function better during obesity

A high-fat diet makes your fat cells larger, inflamed and dysfunctional, putting you at increased risk for diabetes and cardiovascular disease.

14 Jul 2016

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual.

12 Jul 2016

Urolithin A found in pomegranates may improve muscle strength and endurance during aging

Amazentis SA, an innovative life sciences company applying scientific breakthroughs in nutrition to manage health conditions linked to aging, announced today a collaborative publication in Nature Medicine with the École Polytechnique Fédérale de Lausanne, demonstrating that the Company's lead product candidate, urolithin A, improves mitochondrial and muscle function, resulting in enhanced muscle strength and endurance during aging.

11 Jul 2016

New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

When cells die, whether through apoptosis or necrosis, the DNA and other molecules found in those cells don't just disappear. They wind up in the blood stream, where degraded bits and pieces can be extracted.

8 Jul 2016

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

As the powerhouse of the cells, mitochondria are critical for every organism because of their role in producing energy while also controlling survival, but how they function in cancer is still not completely known.

8 Jul 2016

UCI researchers use new imaging method to measure fat metabolism

A team from the University of California, Irvine and supported by the National Institute of Biomedical Imaging and Bioengineering has used a new imaging technique to measure how people break down dietary fat into products the cells of their bodies can use.

8 Jul 2016

New genetic test provides rapid diagnosis of mitochondrial disease

Newcastle researchers have developed a genetic test providing a rapid diagnosis of mitochondrial disorders to identify the first patients with inherited mutations in a new disease gene.

7 Jul 2016

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.

7 Jul 2016

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine.

6 Jul 2016

Mitochondrial DNA levels may represent accurate, predictive measure of embryo viability in IVF

Despite the claims and counter-claims for new embryo assessment techniques introduced over the past two decades, the search for the holy grail of assisted reproduction - the key to the embryo destined to implant - continues.

4 Jul 2016

Scientists discover link between two genes involved in PD and autoimmune diseases

A study publish in the journal CELL indicates that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.

27 Jun 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.

24 Jun 2016

Mitochondria News and Research

Researchers find promising new therapy for both pediatric and adult cancers

Large study of familial ALS finds new gene variant present in 3% of all patients with disease

New wonder compound offers strong protection against harmful effects of UVA rays

Study offers new hope for preventing chronic lung disease in premature infants

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

UC Davis scientists show how cells control DNA synthesis in mitochondria

Scientists explore ways to make fat cells function better during obesity

Scientists identify timing of major metabolic shift in developing neurons

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Urolithin A found in pomegranates may improve muscle strength and endurance during aging

New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

UCI researchers use new imaging method to measure fat metabolism

New genetic test provides rapid diagnosis of mitochondrial disease

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Mitochondrial DNA levels may represent accurate, predictive measure of embryo viability in IVF

Scientists discover link between two genes involved in PD and autoimmune diseases

Mutant fruit flies provide insight into origins of Parkinson's disease

Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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