Mitochondria News and Research

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UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

A UAlberta team has discovered that a protein that plays a critical role in metabolism, the process by which the cell generates energy from foods, is important for the development of pulmonary hypertension, a deadly disease.

30 Oct 2014

Whole exome sequencing can assist in early diagnosis of various disorders

Approximately one-fourth of the 3,386 patients whose DNA was submitted for clinical whole exome testing received a diagnosis related to a known genetic disease, often ending a long search for answers for them and their parents, said researchers from the Baylor College of Medicine departments of molecular and human genetics and pediatrics and the Baylor Human Genome Sequencing Center and the University of Texas Health Science Center at Houston.

20 Oct 2014

Penn State scientists find that mitochondrial disease more prevalent in older moms

The discovery of a "maternal age effect" by a team of Penn State scientists that could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells -- and the transmission of these mutations to children -- could provide valuable insights for genetic counseling.

14 Oct 2014

Synthetic oil triheptanoin improves Rett syndrome, longevity

When young mice with the rodent equivalent of a rare autism spectrum disorder (ASD), called Rett syndrome, were fed a diet supplemented with the synthetic oil triheptanoin, they lived longer than mice on regular diets. Importantly, their physical and behavioral symptoms were also less severe after being on the diet, according to results of new research from The Johns Hopkins University.

10 Oct 2014

Researchers discover mitochondrial and nuclear tRNA-lookalikes in human genome

Transfer RNAs (tRNAs) are ancient workhorse molecules and part of the cellular process that creates the proteins, critical building blocks of life that keep a cell running smoothly.

9 Oct 2014

Power grid failure inside injured cardiac cells triggers post-heart attack arrhythmias

Heart attack survivors often experience dangerous heart rhythm disturbances during treatment designed to restore blood flow to the injured heart muscle, a common and confounding complication of an otherwise lifesaving intervention.

9 Oct 2014

Modified form of niclosamide drug may hold key to battling type 2 diabetes

Type 2 diabetes affects an estimated 28 million Americans according to the American Diabetes Association, but medications now available only treat symptoms, not the root cause of the disease.

6 Oct 2014

Chronic consumption of melatonine helps combat obesity, diabetes

Scientists at the University of Granada, in collaboration with La Paz University Hospital in Madrid and the University of Texas, San Antonio in the US have demonstrated through several experiments conducted on Zucker obese rats that chronic consumption of melatonine helps combat obesity and diabetes mellitus type two.

3 Oct 2014

UCLA research may lead to novel treatment for PH1

Research by UCLA biochemists may lead to a new treatment - or even a cure - for PH1, a rare and potentially deadly genetic kidney disease that afflicts children. Their findings also may provide important insights into treatments for Parkinson's disease, Alzheimer's disease and other degenerative diseases.

27 Sep 2014

Mfn2 protein: A future therapeutic target for neuronal death reduction in ischemic stroke

A new study published in the prestigious publication The EMBO Journal shows that the mitochondrial protein Mfn2 may be a future therapeutic target for neuronal death reduction in the late phases of an ischemic stroke.

24 Sep 2014

New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model to study such illnesses.

22 Sep 2014

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden.

18 Sep 2014

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Iron is a key nutrient for nearly all living organisms, including bacteria. Iron is a cofactor for many enzymes necessary for basic metabolic reactions such as DNA synthesis and electron transport. Iron serves as the conduit for the electron transport chain that generates the energy necessary to drive the bacterial cell.

16 Sep 2014

Agents targeting mitochondrial metabolism can have activity in leukemia

Results of a Phase I clinical trial showed that a new drug targeting mitochondrial function in human cancer cells was safe and showed some efficacy.

9 Sep 2014

Freiburg biochemists discover new mechanisms of brain disease

The failing in the work of nerve cells: An international team of researchers led by Prof. Dr. Chris Meisinger from the Institute of Biochemistry and Molecular Biology of the University of Freiburg has discovered how Alzheimer's disease damages mitochondria, the powerhouses of the cell.

29 Aug 2014

Mitochondria News and Research

UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

Whole exome sequencing can assist in early diagnosis of various disorders

Penn State scientists find that mitochondrial disease more prevalent in older moms

Synthetic oil triheptanoin improves Rett syndrome, longevity

Researchers discover mitochondrial and nuclear tRNA-lookalikes in human genome

Power grid failure inside injured cardiac cells triggers post-heart attack arrhythmias

Modified form of niclosamide drug may hold key to battling type 2 diabetes

Chronic consumption of melatonine helps combat obesity, diabetes

UCLA research may lead to novel treatment for PH1

Mfn2 protein: A future therapeutic target for neuronal death reduction in ischemic stroke

New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Agents targeting mitochondrial metabolism can have activity in leukemia

Freiburg biochemists discover new mechanisms of brain disease

Researchers show how interplay between nutrition, metabolism, immunity involved in ageing process

Reduce inflammatory reaction by losing weight, says researcher

Study suggests autophagy is involved in the onset of vascular dementia

Researchers discover how arginine starvation specifically kills cancer cells

Biologists identify signaling pathway that switches on calorie-burning process in brown fat cells

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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