Mitosis News and Research

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Scientists move a step closer to translating BubR1 protein's function into potential cancer therapy

In a paper published recently in the journal eLife, Mayo Clinic scientists take a step toward translating the protein BubR1's function into a potential therapy for cancer.

24 Aug 2016

Geneticists identify enzyme that regulates chromosome segregation during meiosis

GENETICISTS have identified an enzyme which regulates the production of sperm and egg cells in human reproduction.

10 Aug 2016

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors -- even as it changed the lives of the babies born with it during the pre-Zika era.

8 Aug 2016

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%.

4 Aug 2016

Compounds extracted from parsley and dill seeds may help fight cancer

A team of Russian scientists from Moscow Institute of Physics and Technology, the N. D. Zelinsky Institute of Organic Chemistry, the Institute of Developmental Biology, and the Institute of Cell Biophysics proposed an efficient approach to a novel agents with anticancer activity.

29 Jun 2016

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

The protein complex that holds strands of DNA in compact spools partially disassembles itself to help genes reveal themselves to specialized proteins and enzymes for activation, according to Rice University researchers and their colleagues.

22 Jun 2016

Diet modification could help improve quality of life in women with ovarian cancer

New research conducted at the University of Alabama at Birmingham has shown that a particular type of diet could help women with ovarian cancer to lose weight and improve their quality of life and cancer-related measures.

16 Jun 2016

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

A tension-sensitive "fail safe" protein helps make sure that when our cells divide the two resulting cells inherit the normal number of chromosomes, researchers from the University of Washington and the Fred Hutchinson Cancer Research Center report today, May 5, in the journal Cell.

6 May 2016

Novel function of PLK1 gene in prostate cancer metastasis

Researchers at VCU Massey Cancer Center have uncovered a novel function of the gene PLK1 (polo-like kinase 1) that helps prostate cancer cells metastasize (spread) to other parts of the body. This mechanism highlights new potential targets for cancer therapies and challenges the previous understanding of PLK1's role in cancer growth and progression.

22 Apr 2016

Researchers elucidate how cells are blind to chromosome cohesion defects

Research led by Raquel Oliveira, group leader at Instituto Gulbenkian de Ciência, has elucidated how cells are almost blind to chromosome cohesion defects.

24 Mar 2016

Researchers analyze how Topo II enzyme may affect stability of genomes

While researchers are now familiar with how cancer begins—cells mutate and then multiply wildly out of control—it is still uncertain exactly how that mutation starts in the molecules of the cells.

22 Feb 2016

Bitplane announces launch of Imaris 8.2 with ImarisLineage at ASCB 2015

Bitplane, an Oxford Instruments Company and world leader in 2 to 4D image visualization, analysis and interpretation, has announced the launch of Imaris 8.2 at the American Society for Cell Biology Annual Meeting in San Diego on December 13, 2015.

21 Dec 2015

Bitplane announces launch of Imaris 8.2 with ImarisLineage at ASCB 2015

21 Dec 2015

TBK1 protein plays vital role in the process of cell division

Moffitt Cancer Center researchers have found that a protein called TBK1 plays an important role in the process of cell division, especially at a stage called mitosis.

11 Dec 2015

Textbook view of the human cell cycle needs to be revised, shows new Danish research

Ground-breaking new Danish research has shown that the current scientific description of the human cell cycle needs to be revised. These findings could also lead to the development of new therapeutic approaches to target an Achilles' heel in different types of cancers.

9 Dec 2015

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection.

8 Dec 2015

New nanocarriers may effectively deliver therapeutic drug to GBM tumors

Glioblastoma multiforme, a cancer of the brain also known as "octopus tumors" because of the manner in which the cancer cells extend their tendrils into surrounding tissue, is virtually inoperable, resistant to therapies, and always fatal, usually within 15 months of onset.

20 Nov 2015

Research: Spindle matrix protein supports assembly of spindle matrix, microtubules in cell-division process

Every high school biology class learns about the tiny cells that comprise our bodies, as well as about many of the diverse actions that they perform.

18 Sep 2015

Researchers identify genome-organizing mechanism that transmits vital genetic materials during mitosis

Chromosomes are responsible for carrying our genes and essentially protecting the information that helps ensure normal, healthy growth, with vital instructions being passed on from cell to cell by a process known as mitosis. While this copying mechanism has been well understood for decades, scientists have been unable to describe exactly how genetic information is protected and properly segregated as mitosis is happening.

7 Aug 2015

USC researchers develop yeast model to study gene mutation that disrupts DNA duplication

Researchers at USC have developed a yeast model to study a gene mutation that disrupts the duplication of DNA, causing massive damage to a cell's chromosomes, while somehow allowing the cell to continue dividing.

7 Aug 2015

Mitosis News and Research

Scientists move a step closer to translating BubR1 protein's function into potential cancer therapy

Geneticists identify enzyme that regulates chromosome segregation during meiosis

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

Compounds extracted from parsley and dill seeds may help fight cancer

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

Diet modification could help improve quality of life in women with ovarian cancer

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

Novel function of PLK1 gene in prostate cancer metastasis

Researchers elucidate how cells are blind to chromosome cohesion defects

Researchers analyze how Topo II enzyme may affect stability of genomes

Bitplane announces launch of Imaris 8.2 with ImarisLineage at ASCB 2015

Bitplane announces launch of Imaris 8.2 with ImarisLineage at ASCB 2015

TBK1 protein plays vital role in the process of cell division

Textbook view of the human cell cycle needs to be revised, shows new Danish research

NEK7 enzyme acts as on-off switch in innate immune system

New nanocarriers may effectively deliver therapeutic drug to GBM tumors

Research: Spindle matrix protein supports assembly of spindle matrix, microtubules in cell-division process

Researchers identify genome-organizing mechanism that transmits vital genetic materials during mitosis

USC researchers develop yeast model to study gene mutation that disrupts DNA duplication

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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