Molecular Diagnostics News and Research

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ATS publishes new clinical practice guideline on community-acquired pneumonia

In its latest clinical practice guideline on community-acquired pneumonia the American Thoracic Society's guidelines panel addresses the use of nucleic acid-based testing for non-influenza viral pathogens.

4 May 2021

Novel platform has potential to detect many disease-related biomarkers in just one test

Most conventional molecular diagnostics usually detect only a single disease-related biomarker. Great examples are the PCR tests currently used to diagnose COVID-19 by detecting a specific sequence from SARS-CoV-2.

28 Apr 2021

New COVID-19 testing strategy can quicken test results for healthcare workers

Fast turnaround of COVID-19 test results for healthcare workers is critical. Investigators have now developed a COVID-19 testing strategy that maximizes the proportion of negative results after a single round of testing, allowing prompt notification of results.

26 Apr 2021

Ultrasonically oscillating needles could improve cancer management

The diagnosis of diseases like cancer almost always needs a biopsy - a procedure where a clinician removes a piece of suspect tissue from the body to examine it, typically under a microscope.

21 Apr 2021

New blood-based test detects lymph node metastasis in individuals with high-risk T1 colorectal cancer

Scientists at City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, have developed a novel, noninvasive liquid biopsy test for detecting lymph node metastasis in individuals with high-risk T1 colorectal carcinoma.

21 Apr 2021

New genetic link to male infertility found

The findings published in eLife show that men with this unstable subtype of the Y chromosome have a significantly increased risk of genomic rearrangements.

1 Apr 2021

Adequate reimbursement for molecular diagnostic tests can improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today released the results of its qualitative and quantitative "Analysis of Professional Work Effort in Molecular Test Interpretation Report."

17 Mar 2021

Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

Biomarker testing surveys specific disease-associated molecules to predict treatment response and disease progression; however its use has complicated the diagnosis of non-small-cell lung cancer (NSCLC).

15 Mar 2021

Promega launches XpressAmp™ Direct Amplification Reagents

Promega Corporation has released XpressAmp™ Direct Amplification Reagents that facilitate RNA extraction-free sample preparation that is automation-friendly.

From Promega Corporation 11 Mar 2021

Analysis shows moderate evidence for SARS-CoV-2 recombination

Recently, a team of researchers from the US performed a comprehensive recombination analysis across all medically relevant human coronaviruses, including 158,118 public seasonal hCoV, SARS-CoV-1, SARS-CoV-2, and MERS-CoV genome sequences with the help of the RDP4 software. They aimed at identifying the current and future risks of the emergence of recombinants of SARS-CoV-2

10 Mar 2021

AMP survey results indicate significant decline in molecular diagnostic testing

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today released the preliminary results of its "Molecular Testing for Cancer during COVID-19" survey of clinical laboratories.

23 Feb 2021

Beckman Coulter Life Sciences established as first us distributor of genedrive plc COVID-19 kit

As the world continues to seek solutions in response to the coronavirus pandemic, Beckman Coulter Life Sciences announces it is the first United States distributor of the Genedrive® 96 SARS-CoV-2 kit. The agreement with the near-patient molecular diagnostics company, genedrive plc (LSE: GDR), is for distribution in the US and throughout Europe.

From Beckman Coulter Life Sciences - Flow Cytometry 23 Feb 2021

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer.

18 Feb 2021

New zebrafish model could help advance glioblastoma multiforme research

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor - fewer than one in 20 patients survive five years after diagnosis.

13 Feb 2021

Tecan and UgenTec partner to offer sample-to-result solutions for qPCR

Tecan and laboratory software specialist UgenTec have announced a collaboration to develop fully integrated, sample-to-result solutions for PCR workflows.

From Tecan 9 Feb 2021

New ACR Steering Committee established to guide diagnostic testing during COVID-19 pandemic

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today announced the formation of the AMP COVID Response (ACR) Steering Committee to help coordinate and communicate the organization's continued efforts to guide diagnostic testing during the ongoing COVID-19 pandemic and preparations for future emerging outbreaks.

27 Jan 2021

A single genetic test can identify the presence and cause of mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers.

21 Jan 2021

Pioneering new eye test may predict wet AMD three years before symptoms develop

A pioneering new eye test, developed by scientists at UCL in collaboration with the Western Eye Hospital, London, may predict wet AMD, a leading cause of severe sight loss, three years before symptoms develop.

18 Dec 2020

SARS-CoV-2 genetic material can be reliably detected in self-collected saliva samples

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have found that SARS-CoV-2 genetic material can be reliably detected in self-collected saliva samples at a rate similar to that of nasopharyngeal and oropharyngeal swabs.

11 Dec 2020

Overcoming pediatric drug-resistant TB crisis

World Children's Day marks the day, over three decades ago, on which world leaders adopted the historic Convention of the Rights of the Child, promising to every child to promote and protect their rights, including the right to life and the right to health.

30 Nov 2020