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New antifungal molecule shows promise in combatting fungal infections without toxicity

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

8 Nov 2023

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer's disease in its earliest stages, according to research published in the September issue of The Journal of Nuclear Medicine.

29 Sep 2023

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to human epidermal growth factor receptor 2 (HER2)-targeted treatment in HER2-positive metastatic breast cancer patients, according to new research published in the September issue of The Journal of Nuclear Medicine.

27 Sep 2023

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases.

25 Sep 2023

New consensus statement provides guidance for use of 177Lu-PSMA radionuclide therapy in mCRPC patients

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement to provide standardized guidance for the selection and management of metastatic castrate-resistant prostate cancer (mCRPC) patients being treated with 177Lu-PSMA radionuclide therapy.

5 Sep 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

Rutgers scientists discover first lipid vascular 'zip code' in the lungs

Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular 'ZIP code' in the lungs.

16 Aug 2023

PSMA PET/CT can diagnose advanced prostate cancer in elderly patients without biopsy

In elderly patients with suspected prostate cancer, PSMA PET/CT can diagnose advanced disease and aid in therapy selection without the need for a biopsy.

14 Aug 2023

Tau PET shows promise for early diagnosis and treatment of Alzheimer's disease

Alzheimer's disease, one of the most common neurodegenerative diseases, leads to progressive loss of memory and autonomy.

9 Aug 2023

Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the single-molecule level

A group of researchers investigated single-molecule electrical detection of ribonucleic acid (RNA) cancer biomarkers.

3 Aug 2023

New radionuclide-based agent offers hope for treating a variety of cancers

A newly discovered radionuclide-based agent (CB-2PA-NT) has been shown to have high tumor uptake, sustained tumor retention, and high contrast in preclinical models, making it a prime candidate for a novel theranostics approach.

27 Jun 2023

Novel PET radiotracer shows high sensitivity, specificity in diagnosing coronary artery disease in obese patients

A novel PET perfusion radiotracer, 18F-flurpiridaz, can diagnose coronary artery disease (CAD) in obese patients with a higher sensitivity and specificity compared to 99mTc-SPECT myocardial perfusion imaging (MPI), according to research presented at the 2023 Society of Nuclear Medicine and Molecular Imaging Annual Meeting. 18F-flurpiridaz PET MPI obtained images at a lower radiation dose than 99mTc-SPECT MPI and performed similarly in both obese and non-obese patients.

27 Jun 2023

Personalized dosing improves outcomes for men with metastatic castration-resistant prostate cancer

By monitoring early-response biomarkers in men undergoing 177Lu-PSMA prostate cancer treatment, physicians can personalize dosing intervals, significantly improving patient outcomes.

26 Jun 2023

New computational technique shows promise for identifying different subtypes of Alzheimer's disease

A new computational technique that combines genomic and tau PET imaging data promises a more personalized approach for subtyping Alzheimer's disease.

26 Jun 2023

New white paper on challenges and opportunities in theranostics education

Leaders from 12 nuclear medicine organizations around the world have issued a white paper about the challenges and opportunities in theranostics education.

23 Jun 2023

Study reveals why some women with deadly ovarian cancer respond better to treatment than others

New research is increasing our understanding about why some women with the most lethal form of ovarian cancer respond much better to treatment than others.

21 Jun 2023

Study finds altered gut bacteria in people with early signs of Alzheimer's disease

People in the earliest stage of Alzheimer's disease -; after brain changes have begun but before cognitive symptoms become apparent -; harbor an assortment of bacteria in their intestines that differs from the gut bacteria of healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis.

14 Jun 2023