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Enzymatic cocktail emerges as new hope against mycobacterial infections

With resistance to chemical antibiotics on the rise, the world needs entirely new forms of antibiotics. A new study published in Microbiology Spectrum, a journal of the American Society for Microbiology, shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.

27 Mar 2024

New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Project will be a demonstration of how Ubiquigent’s DUB-centric platform can support the development of DUB inhibitors all the way from discovery through to clinical development.

From Ubiquigent Limited 26 Mar 2024

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers at the University of Leeds and Lancaster University in the UK have identified a new potential target for the treatment of Alzheimer's disease – PDE4B.

26 Mar 2024

Researchers identify viable vaccine targets for hepatitis C infections

By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.

26 Mar 2024

Researchers develop a novel sensor for the detection of bacteria

Each year, bacterial infections claim several million lives worldwide. That is why detecting harmful microorganisms is crucial – not only in the diagnosis of diseases but also, for example, in food production.

25 Mar 2024

Generative artificial intelligence model can easily design billions of novel antibiotics

Researchers at McMaster University and Stanford University have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.

22 Mar 2024

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.

22 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Boosting mRNA activity and longevity with multi-tailed structures

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines

22 Mar 2024

Natural molecule trigonelline can help to improve muscle health and function

A research consortium led by Nestlé Research in Switzerland and the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) made a recent discovery that the natural molecule trigonelline present in coffee, fenugreek, and also in the human body, can help to improve muscle health and function.

22 Mar 2024

Innovative study on asthma inflammation funded by NIH/NIAID grant

In a significant stride for respiratory medicine, Lundquist Institute (TLI) investigator Nicholas Jendzjowsky, PhD, has been awarded a prestigious grant from the National Institute of Health/National Institute of Allergy and Infectious Diseases (NIH/NIAID).

21 Mar 2024

Aging affects regulatory T cells' ability to promote myelin regeneration

Regulatory T lymphocytes are cells that are responsible for regulating the immune system and have regenerative functions in many contexts, including myelin restoration.

20 Mar 2024

Nuclera joins Tech Nation’s Future Fifty program

Nuclera recognized as one of UK’s most exciting growth stage companies.

From Nuclera 20 Mar 2024

Ketogenic diet delays the early stages of Alzheimer's-related memory loss in mice

A new study from researchers at the University of California, Davis, shows a ketogenic diet significantly delays the early stages of Alzheimer's-related memory loss in mice.

19 Mar 2024

CRISPR-based diagnostics for rapid oral pathogen detection

A study aiming to develop a low-cost, rapid detection technique for the widescale detection and screening of oral microorganisms suitable for point-of-care settings was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

New drug candidates show promise to reverse HIV immune evasion

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

19 Mar 2024

Research unveils a cellular shield against harmful effects of UV-induced RNA damage

UV radiation in the sunlight causes sunburn and increases the risk of skin cancer by damaging our DNA but also our RNA.

18 Mar 2024

Lab-synthesized heparin to transform drug manufacturing

Heparin, the world's most widely used blood thinner, is used during procedures ranging from kidney dialysis to open heart surgery.

18 Mar 2024

Study reveals the inner workings of gene mutations linked to ultra-rare syndrome

A team from the University of Ottawa's Faculty of Medicine has completed an exciting new study that reveals the inner workings of gene mutations that result in an ultra-rare syndrome with fewer than 100 reported cases since its first description in the early 1960s.

18 Mar 2024

Molecule News and Research

Enzymatic cocktail emerges as new hope against mycobacterial infections

New insights into the exacerbation of psoriasis through specific genetic defects

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers identify viable vaccine targets for hepatitis C infections

Researchers develop a novel sensor for the detection of bacteria

Generative artificial intelligence model can easily design billions of novel antibiotics

Researchers create new platform to identify proteins for targeted treatment of disease

Study shows cellular, molecular overlaps in ALS and FTLD

Boosting mRNA activity and longevity with multi-tailed structures

Natural molecule trigonelline can help to improve muscle health and function

Innovative study on asthma inflammation funded by NIH/NIAID grant

Aging affects regulatory T cells' ability to promote myelin regeneration

Nuclera joins Tech Nation’s Future Fifty program

Ketogenic diet delays the early stages of Alzheimer's-related memory loss in mice

CRISPR-based diagnostics for rapid oral pathogen detection

New drug candidates show promise to reverse HIV immune evasion

Research unveils a cellular shield against harmful effects of UV-induced RNA damage

Lab-synthesized heparin to transform drug manufacturing

Study reveals the inner workings of gene mutations linked to ultra-rare syndrome

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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