Mosquito News and Research

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MVI agrees to provide fund for evaluating Inovio's malaria DNA vaccine candidate in non-human primates

Inovio Pharmaceuticals, Inc., a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that the PATH Malaria Vaccine Initiative (MVI) has agreed to provide follow-on funding to continue evaluation and development of Inovio's malaria DNA vaccine candidate in non-human primates.

15 Sep 2010

Also in Global Health News: GM mosquitoes; Iodine deficiency in Nepal; South African health workers strike; Novartis to build vaccine plant in Brazil; Population control in Niger

Malaysia is still "considering releasing" up to 3,000 mosquitoes that are genetically modified to "combat dengue fever, in a landmark field trial that has come in for criticism from environmentalists," Agence France-Presse reports. The insects are modified "so that their offspring quickly die," which researchers hope will cull the population and lessen the risk of dengue.

30 Aug 2010

Department of Health reports 2010's first human case of West Nile virus in Pennsylvania

The Department of Health today reported this year's first human case of West Nile virus in Pennsylvania. The individual is a 69-year-old man from Philadelphia County.

26 Aug 2010

Study on current insect repellants confirms need for better insect repellants

Fire up the citronella-scented tiki torches, and slather on the DEET: Everybody knows these simple precautions repel insects, notably mosquitoes, whose bites not only itch and irritate, but also transmit diseases such as West Nile virus, malaria and dengue. Now, Johns Hopkins scientists have discovered what it is in the bugs' molecular makeup that enables citronellal (the aromatic liquid used in lotions, sprays and candles) and DEET, to deter insects from landing and feeding on you. A better understanding of these molecular-behavioral links already is aiding the team's search for more effective repellants.

26 Aug 2010

Bug with bifocals discovered

University of Cincinnati researchers are reporting on the discovery of a bug with bifocals - such an amazing finding that it initially had the researchers questioning whether they could believe their own eyes. "To the best of our knowledge, this is the first demonstration of truly bifocal lenses in the extant animal kingdom," the researchers state in the Aug. 24 cover feature of the premier life-science journal, Current Biology.

24 Aug 2010

Scientists identify compound to treat Chagas' disease

A new compound may offer an effective drug candidate against the deadly tropical infection, Chagas' disease say researchers from Brazil. They report their findings in the August 2010 issue of the journal Antimicrobial Agents and Chemotherapy.

21 Aug 2010

IR USA increases fundraising goal for Pakistan flood victims to $4M

Islamic Relief USA, a Washington, D.C.-based relief and development organization, today announced that it has increased its fundraising goal for the Pakistan flood victims to $4 million due to the worsening conditions in the region. It has also collected more than $23 million in in-kind donations.

19 Aug 2010

Rush University Medical Center tests new drug therapy for West Nile fever

Neurological and infectious disease experts at Rush University Medical Center are testing a new drug therapy for the treatment of individuals with West Nile fever or suspected central nervous system infection due to the West Nile virus. Rush is the only site in the Midwest enrolling patients into the $50 million dollar, NIH-funded, Phase II clinical trial called PARADIGM.

18 Aug 2010

Red Cross and Canadian International Development Agency deploy $1M in emergency supplies to Pakistan

As a collaborative effort, the Canadian Red Cross, along with the Canadian International Development Agency, has deployed $1 million of emergency supplies to the flood affected communities in Pakistan. Once in Pakistan, the stocks will be distributed by local volunteers through the Red Cross Red Crescent network.

18 Aug 2010

Mathematical model projects potential impact of current tools fighting malaria in Africa

Current tools for combating malaria, such as artemisinin-based combination therapy (ACT) and increasing coverage of long-lasting insecticide treated nets (LLINs) insecticide-treated bednets (ITN) "could dramatically reduce the burden of malignant malaria on parts of Africa if a comprehensive, sustained intervention programme were in place," according to a study published this week in PLoS Medicine, CORDIS News reports.

16 Aug 2010

U.S. increases Pakistan flood aid contribution; Sen. Kerry to visit flood-hit Pakistan

"On assistance to Pakistan, to date, approximately $76 million in assistance has been provided by the U.S. to the flood-affected populations in Pakistan," Mark Toner, acting deputy spokesman for the State Department, said at a press briefing on Thursday, according to a transcript. "As of this morning, the additional money that the U.S. is providing is to Save the Children, and that's 4.1 million that will be used for food vouchers, enabling flood victims to purchase food in their local markets," he said.

16 Aug 2010

Combination of fungi, insecticides can combat malaria mosquitoes: Research

A combination of fungal spores and chemical insecticides are an effective way of combating insecticide-resistant malaria mosquitoes. Researchers at Wageningen UR and from Benin, West Africa, have shown that fungi and insecticides reinforce each other´s efficacy, and that the effect of using a combination of both is greater than the sum of using the two methods separately. Their article in the August edition of PLoS One (Public Library of Science) claims that biological and chemical methods of fighting malaria can and should be used together.

13 Aug 2010

Needle-free natural vaccine against malaria: Research

A study published in the journal Science Translational Medicine proposes that preventative treatment with affordable and safe antibiotics in people living in areas with intense malaria transmission has the potential to act as a 'needle-free' natural vaccine against malaria and may likely provide an additional valuable tool for controlling and/or eliminating malaria in resource-poor settings.

12 Aug 2010

NIH begins human clinical testing for dengue virus vaccine

After more than a decade of development at the National Institutes of Health, a vaccine to prevent infection by the mosquito-borne dengue virus has begun human clinical testing. The vaccine was developed by scientists at the National Institute of Allergy and Infectious Diseases (NIAID) and is undergoing clinical study at the Johns Hopkins Bloomberg School of Public Health in Baltimore.

10 Aug 2010

Researchers map malaria parasite P vivax; Nearly 3B people at risk of infection in 2009

A new evidence-based map estimates that in 2009 2.85 billion people lived "at risk of infection" with the malaria parasite Plasmodium vivax, BMJ News reports. As described in a study, published Tuesday in PLoS Neglected Tropical Diseases, P vivax "is more widespread and potentially represents a greater burden on human health in some parts of the world than P falciparum, the species usually associated with the greatest mortality and morbidity," BMJ News writes (Moszynski, 8/3).

5 Aug 2010

African leaders agree to expand maternal health campaign as AU Summit concludes

African leaders participating in the 15th African Union Summit, which concluded on Tuesday, agreed to expand a campaign aimed at curbing maternal mortality on the continent and adopted other "key actions" in an effort to reduce infant and maternal mortality, PANA/Afrique en ligne reports.

29 Jul 2010

Dengue fever emerges as major health threat in Gulf coast cities

Several cases of dengue fever, a potentially fatal viral disease transmitted by the bite of urban dwelling Aedes aegypti and Aedes albopictus mosquitoes, have recently been reported in the continental United States. Prevalent in Central America and the Caribbean, dengue fever's most common symptoms include fever, chills, headache, and body aches lasting several days. The disease's more threatening form, dengue hemorrhagic fever, can cause internal bleeding, loss of blood pressure, and death. Over the past five years, outbreaks of both forms of the disease have been reported in Texas and Florida.

28 Jul 2010

Predator-released chemicals function as warning signals for egg-laying mosquitoes

A scientific breakthrough might assist in the fight against mosquitoes. New research carried out at the University of Haifa in collaboration with researchers from other universities has chemically identified, for the first time, compounds released by mosquitoes' natural aquatic predators that function as warning signals for egg laying mosquitoes. Introducing these natural chemicals into mosquito breeding sites will cause the mosquitoes to sense risk of predation to their progeny and avoid laying their eggs there.

22 Jul 2010

Opinions: AIDS vaccine and cure; China's role in the Global Fund; Child marriage prevention act; Gorbachev on safe water

A Globe and Mail editorial discusses the importance of "the quest for an AIDS vaccine and the search for a cure," stating that "it is simply not possible to 'treat' our way out of this disease." The authors write that "for every person who receives treatment - which must continue over their entire lifetime - about three new people become infected."

21 Jul 2010

Natural, needle-free vaccination against malaria

If mice are administered an antibiotic for three days and are simultaneously infected with malaria, no parasites appear in the blood and life-threatening disease is averted. In addition, the animals treated in this manner also develop robust, long-term immunity against subsequent infections. This discovery was made by the team headed by Dr. Steffen Borrmann from the Department of Infectious Diseases at Heidelberg University Hospital in cooperation with Dr. Kai Matuschewski of the Max Planck Institute for Infection Biology in Berlin. The scientists think that safe and affordable prophylaxis with antibiotics in residents of areas with high malaria transmission has the potential to be used as a natural "needle-free" vaccination against malaria.