Motor Neurone Disease

The motor neurone diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body.

What is Motor Neurone Disease?

Motor neurone disease is a rare condition of the nervous system that leads to loss of muscle control. The disease leads to progressive weakness, muscle wastage and eventually disability.

Motor Neurone Disease Causes

Motor Neurone Disease Diagnosis

Motor Neurone Disease Symptoms

Motor Neurone Disease Epidemiology

Motor Neurone Disease Etymology

Motor Neurone Disease Pathophysiology

Motor Neurone Disease Prognosis

Motor Neurone Disease Treatment

Motor Neurone Disease Complications

Motor Neuron Disease: Can Dietary Supplements Help?

Types of Motor Neuron Disease and Their Causes

Latest Motor Neurone Disease News and Research

Scientists uncover key protein aggregation in frontotemporal dementia

Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids.

6 Dec 2023

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

21 Jul 2023

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King's College London and the University of Bath in the UK.

16 Nov 2022

Over £800 million to support improved healthcare delivery and breakthroughs in new treatments

Patients up and down the country are set to benefit from innovative new treatments and improved delivery of health and care services following significant funding to support ground-breaking experimental medicine research and advance the UK's response to patient safety challenges.

14 Oct 2022

Clinical suite to help unlock the mysteries of neurological disorders

A clinical suite at a University of Queensland health research facility is ready to help unlock the mysteries of neurological conditions experienced by one billion people worldwide.

26 Sep 2022

New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

LifeArc and UK DRI launch new partnership to accelerate development of new treatments for dementia

LifeArc and the UK Dementia Research Institute (UK DRI) have today launched a new partnership to accelerate development of new diagnostic tests, treatments, and devices from scientific research discoveries to benefit people with dementia, which around 900,000 people in the UK are living with.

15 Jun 2022

3D-printed bracelet may allow people with hand-impairment to use computers, play video games

People who lack the ability to use their hands from conditions like motor neurone disease and cerebral palsy may one day be able to play video games that require a handheld controller through the use of acustomisable, wearable 3D printed bracelet.

4 May 2022

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Alzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brain, newly published research argues.

8 Apr 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Machine learning model identifies new risk genes for motor neurone disease

Scientists have developed a new machine learning model for the discovery of genetic risk factors for diseases such as Motor Neurone Disease (MND).

18 Jan 2022

Novel biomarker can be used to identify disease progression in ALS

An international collaboration led by Flinders University has identified a potential biomarker for amyotrophic lateral sclerosis, also known as Motor Neuron Disease, providing a way to test the effectiveness of future clinical trials.

13 Jan 2022

£375 million Government funding to improve treatment for neurodegenerative diseases

People living with neurodegenerative diseases could live longer, healthier lives due to innovative new research, following a government commitment to invest £375 million over the next 5 years.

14 Nov 2021

Infrared light therapy may potentially benefit people with dementia

Infrared light therapy might have the potential to help people living with dementia, according to researchers.

19 Oct 2021

Brain diseases could have a greater societal impact than Covid-19, research finds

New research has found that brain diseases, such as Parkinson’s and Alzheimer’s, are surfacing earlier, proving more fatal, and could have a greater societal impact than Covid-19.

17 Aug 2021

Newborn screening and early treatment for spinal muscular atrophy can save both lives and money

Gene therapy for spinal muscular atrophy might have a high up-front price tag. But by screening and treating infants early, the therapy can save both lives and money in the long term.

4 Aug 2021

A single blood-based biomarker can help indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive

7 Jun 2021

New technology could allow people with Motor Neurone Disease to communicate via computer

A revolutionary assistive technology being developed by GP Dr Nick Gompertz with a team of researchers at the University of Bath hopes to offer people with conditions such as Motor Neurone Disease (MND) new ways of communicating via a computer.

6 May 2021

Researchers identify the trigger of key cellular change in amyotrophic lateral sclerosis

Scientists at the Francis Crick Institute and UCL have identified the trigger of a key cellular change in amyotrophic lateral sclerosis (ALS), a type of motor neurons disease.

4 Mar 2021

Motor Neurone Disease

Overview

Motor Neurone Disease Causes

Motor Neurone Disease Diagnosis

Motor Neurone Disease Symptoms

Feature Articles

Motor Neurone Disease Epidemiology

Motor Neurone Disease Etymology

Motor Neurone Disease Pathophysiology

Motor Neurone Disease Prognosis

Motor Neurone Disease Treatment

Motor Neurone Disease Complications

Motor Neuron Disease: Can Dietary Supplements Help?

Types of Motor Neuron Disease and Their Causes

Latest Motor Neurone Disease News and Research

Scientists uncover key protein aggregation in frontotemporal dementia

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

Over £800 million to support improved healthcare delivery and breakthroughs in new treatments

Clinical suite to help unlock the mysteries of neurological disorders

New genetically-targeted MND therapy could be a turning point for patient care

Repurposed drug shows promise as potential new treatment for motor neuron disease

LifeArc and UK DRI launch new partnership to accelerate development of new treatments for dementia

3D-printed bracelet may allow people with hand-impairment to use computers, play video games

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Machine learning model identifies new risk genes for motor neurone disease

Novel biomarker can be used to identify disease progression in ALS

£375 million Government funding to improve treatment for neurodegenerative diseases

Infrared light therapy may potentially benefit people with dementia

Brain diseases could have a greater societal impact than Covid-19, research finds

Newborn screening and early treatment for spinal muscular atrophy can save both lives and money

A single blood-based biomarker can help indicate underlying neurodegeneration

New technology could allow people with Motor Neurone Disease to communicate via computer

Researchers identify the trigger of key cellular change in amyotrophic lateral sclerosis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Motor Neurone Disease

Overview

Feature Articles

Motor Neurone Disease Epidemiology

Motor Neurone Disease Etymology

Motor Neurone Disease Pathophysiology

Motor Neurone Disease Prognosis

Motor Neurone Disease Treatment

Motor Neurone Disease Complications

Motor Neuron Disease: Can Dietary Supplements Help?

Types of Motor Neuron Disease and Their Causes

Latest Motor Neurone Disease News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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