Mucous Membrane Pemphigoid News and Research

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Mucous membrane pemphigoid (MMP) encompasses a heterogeneous group of diseases, which predominantly affects the elderly. The peak incidence is at roughly 70 years. However, rare childhood cases have also been reported. There is no racial or ethnic predilection associated with MMP, but the condition does appear to be twice as common in women than it is in men. For completeness, MMP is also termed cicatricial pemphigoid, oral pemphigoid and ocular pemphigoid.

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis.

4 Aug 2016

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients.

4 Aug 2016

Immunosuppressive drug mycophenolate mofetil may be effective in controlling inflammatory eye diseases

The immunosuppressive drug mycophenolate mofetil, used to prevent rejection of transplanted hearts, kidneys and livers, may also be effective in controlling inflammatory eye diseases, according to a study by Johns Hopkins' Wilmer Eye Institute.

4 Sep 2005