Muscle Atrophy News and Research

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Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

The loss of muscle mass and strength during aging is called sarcopenia. Affecting the elderly population, sarcopenia is a degenerative process that brings about a decrease in wellbeing and increased dependency.

22 Mar 2022

Researchers investigate loss of fitness following COVID-19

Researchers investigate if a decline in exercise capabilities is due to deconditioning during infection or long-term reductions in ability due to COVID-19.

15 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

In a new study, researchers analyzed the effects of multi-nutrient supplementation on SARS-CoV-2 vaccine efficacy and the overall improvement of respiratory and muscle function in elderly COVID-19 patients.

27 Jan 2022

New discovery helps explain the persistent weakness after ACL reconstruction surgery

After an anterior cruciate ligament reconstruction surgery, it’s common to experience quadriceps weakness, which was thought to be caused primarily by muscle atrophy, or shrinkage.

2 Nov 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

New mathematical model can predict the optimum exercise regime for building muscle

Researchers have developed a mathematical model that can predict the optimum exercise regime for building muscle.

23 Aug 2021

Study reveals key mechanisms of how physical load stimulates bone growth

When things get too much, we're often advised to "take a load off," but when it comes to bone maintenance, doing the opposite can be a good thing. Researchers from Japan have discovered some key mechanisms of how physical load stimulates bone growth.

15 Jul 2021

An antioxidative stress regulator helps keep muscles from becoming weak in low gravity

Most kids dream of growing up to be astronauts; but the downside of spending extended amounts of time in low gravity is that astronauts' muscles tend to shrink and weaken through disuse. Now, researchers from Japan have identified a protein that affects how muscles respond to space flight.

7 Jul 2021

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis.

30 Jun 2021

Researchers explore effects of reduced gravity on mouse skeletal muscles

Most of us have imagined how free it would feel to float around, like an astronaut, in conditions of reduced gravity. But have you ever considered what the effects of reduced gravity might have on muscles?

11 May 2021

Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

A new hydrogel for treatment and recovery of muscle injuries

A team from the Universitat Politècnica de València (UPV) and the CIBER Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) has designed and tested, at a preclinical level, a new biomaterial for the treatment and recovery of muscle injuries.

31 Mar 2021

Scientists use silk from transgenic silkworm to grow skeletal muscle cells

Researchers at Utah State University are using silkworm silk to grow skeletal muscle cells, improving on traditional methods of cell culture and hopefully leading to better treatments for muscle atrophy.

10 Mar 2021

Hormone known to prevent weight gain can help maintain healthy muscles in mice

A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice.

23 Feb 2021

Elevated Activin A and FLRG levels correlate with worst outcomes in severe COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a "cytokine storm" in hospitalized and ICU patients. Studies have shown that the blockade of cytokine signaling and steroid treatment helps achieve positive outcomes in patients.

15 Feb 2021

Using gene therapy to mimic the effects of physical exercise

It sounds too good to be true - and it is. But Jose Bianco Moreira and the CERG research group at the Norwegian University of Science and Technology are convinced that some of the positive health effects of physical exercise can be achieved using gene therapy and medication.

21 Jan 2021