Muscle Atrophy News and Research

RSS

Researchers identify new strategy to combat loss of skeletal muscle mass

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that stimulating expression of a protein naturally produced by the human body can be a strategy to combat loss of skeletal muscle mass, which happens normally with aging but can intensify in cases of neurodegenerative or inflammatory disease, or in patients who spend long periods in intensive care units (ICUs).

9 Nov 2020

Training one arm can improve strength and decrease muscle loss in the other arm

New research from Edith Cowan University (ECU) has revealed that training one arm can improve strength and decrease muscle loss in the other arm - without even moving it.

23 Oct 2020

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

12 Oct 2020

Mathematical model helps investigate spaceflight mechanisms that induce cardiovascular deconditioning

Human spaceflight has been fascinating man for centuries, representing the intangible need to explore the unknown, challenge new frontiers, advance technology and push scientific boundaries further.

9 Oct 2020

HSS researchers use novel MRI technique to study Parsonage-Turner Syndrome

Researchers at Hospital for Special Surgery (HSS) have received a grant from the National Institutes of Health to use a novel MRI technique known as magnetic resonance neurography, or MRN, to study Parsonage-Turner Syndrome (PTS), a painful nerve disorder that leads to severe weakness.

24 Sep 2020

Ghrelin may help protect the elderly population from muscle loss

The hormone, ghrelin, may help protect the elderly population from muscle loss, according to a study being presented at e-ECE 2020. The study found that administering a particular form of ghrelin to older mice helped to restore muscle mass and strength.

8 Sep 2020

Unexpected discovery helps explain fundamental mystery about how muscles work

Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract, relax, communicate its energy needs, and adapt to exercise.

21 Jun 2020

Study reports structure of enzyme activator for high pathogenic avian influenza

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the current pandemic of COVID-19, is the focus of many investigators seeking to find an effective vaccine or therapeutic. Among the potential targets are various protease enzymes suspected of allowing the virus to gain entry to host cells and establish a successful infection.

16 Jun 2020

High-intensity interval training could be beneficial for people with spinal cord injuries

Research from the Department of Kinesiology at McMaster University has found that the practical advantages of high-intensity interval training (HIIT), or short bursts of all-out exercise, could be especially beneficial for people who have experienced spinal cord injuries (SCI).

11 Jun 2020

Adding eccentric exercises could improve outcomes for people with ACL injuries

People with anterior cruciate ligament injuries can lose up to 40% of the muscle strength in the affected leg--with muscle atrophy remaining a big problem even after ACL reconstruction and physical therapy.

13 May 2020

Newborn screening for spinal muscular atrophy promises a benefit

On behalf of the Federal Joint Committee, the Institute for Quality and Efficiency in Health Care investigated whether it is meaningful to test newborns in Germany for spinal muscular atrophy in combination with earlier diagnosis and treatment.

6 Apr 2020

Researchers discover glial cells that control stress response, extend lifespan in worms

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating in our muscles, setting us up for muscle atrophy in old age.

23 Feb 2020

Grizzly bears' strategy could help prevent muscle atrophy in humans

Grizzly bears spend many months in hibernation, but their muscles do not suffer from the lack of movement. In the journal "Scientific Reports", a team led by Michael Gotthardt reports on how they manage to do this.

30 Dec 2019

Study uncovers a previously unknown subtype of muscle stem cells

Scientists have discovered a new subtype of muscle stem cells. These cells have the ability to build and regenerate new muscles, making them interesting targets for the development of gene therapies.

21 Dec 2019

Gut microbes may alter the aging process, study finds

An international research team led by Nanyang Technological University, Singapore (NTU Singapore) has found that microorganisms living in the gut may alter the aging process, which could lead to the development of food-based treatment to slow it down.

14 Nov 2019

Study: Natural loss of foot muscles in rodents shares similarities with skeletal muscle atrophy

New insight on how the natural loss of foot muscles occurred in rodents and other species during their evolution has been published today in the open-access journal eLife.

16 Oct 2019

Newly discovered molecular process could speed up recovery from nerve injuries

Twenty million Americans suffer from peripheral nerve injuries, which can be caused by traumas such as combat wounds and motorcycle crashes as well as medical disorders including diabetes.

3 Oct 2019

Review examines the role of biologic agents in management of shoulder and elbow problems

The utilization of stem cell therapies for augmentation of tissue healing has far outpaced the supporting scientific and clinical data, largely due to aggressive marketing that has led to widespread and often inappropriate use of cell therapy approaches in the United States.

1 Oct 2019

Study identifies factor essential for tendon growth

Insulin-like growth factor 1 (IGF1) is essential for allowing tendons to adapt to physical activity and grow properly, according to basic science research by investigators at Hospital for Special Surgery.

24 Sep 2019

Researchers discover how cancer cells can trigger chronic muscle wasting condition

A solid tumor can cause muscle cells in the body to self-destruct. Many cancer patients die from the consequences. Now researchers are discovering more about how cancer cells in a tumor can take control of muscle cell wasting and trigger a chronic, serious condition.

19 Sep 2019