Muscle Atrophy News and Research

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Study explores current understanding of human physiology, pathology, trauma and surgery in space

With renewed public interest in manned space exploration comes the potential need to diagnose and treat medical issues encountered by future space travellers.

20 Jun 2018

Study identifies new mechanism involved in development of Lou Gehrig's disease

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig's disease, or amyotrophic lateral sclerosis.

23 May 2018

HU researchers explore how simulated microgravity affects gene expression, muscle cell differentiation

Astronauts go through many physiological changes during their time in spaceflight, including lower muscle mass and slower muscle development. Similar symptoms can occur in the muscles of people on Earth's surface, too. In fact, it could affect everyone to some extent later in life.

23 May 2018

New study identifies key cellular mechanisms behind vascular aging in mice

We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

22 Mar 2018

Impaired transport processes in neurons contribute to neurodegenerative disorders

Two partners have to find their way to each other in order to transport substances to the remote ends of special nerve fibers to maintain their function. If this partnering process is disturbed, the cells may die in the worst case, resulting in neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy.

9 Mar 2018

HSS researchers win grant to determine if stem cell therapy can improve outcomes for rotator cuff tears

A multidisciplinary team led by Scott Rodeo, MD, and Christopher Mendias, PhD, at Hospital for Special Surgery has been awarded the Orthopaedic Research and Education Foundation Clinical Research Grant in Cellular Therapy in honor of James Urbaniak, MD in Collaboration with National Stem Cell Foundation.

5 Jan 2018

Researcher discovers enzyme pathway involved in ALS pathogenesis

It is estimated that between 14,000 and 15,000 Americans have amyotrophic lateral sclerosis (ALS), according to the National Institutes of Health. Symptoms of ALS, also known as Lou Gehrig's disease, may be subtle at first but develop into more obvious muscle weakness and paralysis.

5 Dec 2017

New implantable muscle stimulator aims to prevent pressure ulcers, deep tissue injuries

A team of researchers led by Kath Bogie, DPhil (PhD), a biomedical engineer and associate professor of orthopaedics and biomedical engineering at Case Western Reserve University School of Medicine, and colleagues from Case Western Reserve and other institutions, has received a $1.8M, three-year grant from the U.S. Department of Defense to develop an implantable muscle stimulator for preventing pressure ulcers and deep tissue injuries to the buttocks.

15 Nov 2017

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation.

26 Oct 2017

Single infusion of wildtype HSPCs halts cellular damage caused by neuromuscular disorder in mice

Researchers at University of California San Diego School of Medicine report that a single infusion of wildtype hematopoietic stem and progenitor cells (HSPCs) into a mouse model of Friedreich's ataxia (FA) measurably halted cellular damage caused by the degenerative disease.

25 Oct 2017

Arkansas professor makes strides toward developing enhanced cancer treatment

A University of Arkansas at Little Rock professor is making strides toward developing an effective cancer treatment without the severe side effects of traditional therapies.

13 Sep 2017

Leading experts come together to discuss clinical, translational applications of mitochondria

The American Physiological Society will host the "Physiological Bioenergetics: Mitochondria from Bench to Bedside" conference August 27–30 in San Diego. The meeting will bring together cross-disciplinary experts who study the mitochondria, which provide the energy to individual cells.

23 Aug 2017

Timely diagnosis and treatment of carpal tunnel syndrome can prevent long-lasting damage

The sooner carpal tunnel syndrome is diagnosed and treated, the better the chances for symptom relief, according to experts at Hospital for Special Surgery in New York City.

4 Aug 2017

Natural compounds in thyme and oregano may offer treatment for cachexia

Fresh thyme and oregano offer a savory touch to a tasty dish, but a University of Iowa researcher recently discovered natural compounds in the herbs that may offer a treatment for cachexia or "wasting syndrome" as it is more commonly known.

1 Aug 2017

Mildly stressing muscle metabolism reverses diabetes and obesity in mice

Mildly stressing muscle metabolism boosts levels of a beneficial hormone that prevents obesity and diabetes in mice, according to a new study by researchers at the University of Iowa.

28 Jun 2017

Researchers uncover new potential target for treating spinal muscular atrophy

Though spinal muscular atrophy in its most severe form remains incurable and fatal in early childhood, researchers are sustaining a multipronged counterattack for patients and their families. The first treatment for the disease gained U.S. market approval in December.

2 May 2017

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

In a recent paper published in the Journal of Biological Chemistry Yuna Ayala, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, and her research team made advances in understanding how a protein causes damaging plaques to build up in neurodegenerative illnesses like amyotrophic lateral sclerosis (ALS) and a form of dementia called frontotemporal lobar degeneration.

19 Apr 2017