Muscle Atrophy News and Research

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Study on human growth hormone for ACL tear recovery receives funding from Mark Cuban Foundation

Funding from the Mark Cuban Foundation, run by the well-known owner of the Dallas Mavericks, will allow University of Michigan scientists and physicians to study how human growth hormone may aid recovery from an ACL tear - one of the most frequent, traumatic and dreaded knee injuries among athletes.

1 Jun 2015

CyMedica QB1 System now commercially available for treatment of quadriceps muscle atrophy

Scottsdale-based CyMedica Orthopedics, Inc. announced the commercial launch of the CyMedica QB1 System for the treatment of quadriceps muscle atrophy at the Arthroscopy Association of North American Arthroscopic Society for Sports Medicine annual meeting in Los Angeles last week.

29 Apr 2015

Scientists use special MRI imaging to predict chronic pain, disability and PTSD after whiplash injury

While most people should expect to fully recover from whiplash injuries within the first few months, about 25 percent have long-term pain and disability that lasts many months or years.

2 Apr 2015

New insights into the use, outcomes of gluteoplasty and vaginal labiaplasty procedures

Two of the fastest-growing plastic surgery procedures are gluteoplasty or "butt augmentation," to improve the appearance of the buttocks; and labiaplasty to address cosmetic and functional concerns with the vagina.

3 Mar 2015

Isis Pharmaceuticals begins ISIS-DMPK Rx clinical study in DM1 patients

Isis Pharmaceuticals, Inc. announced today that it has initiated a study for ISIS-DMPK Rx in patients with Myotonic Dystrophy Type 1 (DM1). DM1 is a rare genetic neuromuscular disease caused by the production of toxic dystrophia myotonica-protein kinase (DMPK) RNA in cells. ISIS-DMPKRx is specifically designed to reduce toxic DMPK RNA.

16 Dec 2014

Isis Pharmaceuticals announces initiation of ISIS-SMN Rx Phase 3 study in children with SMA

Isis Pharmaceuticals, Inc. announced today the initiation of a pivotal Phase 3 study evaluating ISIS-SMNRx in approximately 120 non-ambulatory children with spinal muscular atrophy (SMA).

25 Nov 2014

Researchers identify molecular switch that controls inflammatory processes in aging-related disorders

A study led by Massachusetts General Hospital (MGH) investigators has identified what appears to be a molecular switch controlling inflammatory processes involved in conditions ranging from muscle atrophy to Alzheimer's disease.

14 Nov 2014

Longer looks: Dying at home; losing religion; Obamacare 2.0

He was still her handsome father, the song-and-dance man of her childhood, with a full head of wavy hair and blue eyes that lit up when he talked. But he was gaunt now, warped like a weathered plank, perhaps by late effects of an old stroke, certainly by muscle atrophy and bad circulation in his legs. Now she was determined to fulfill her father's dearest wish, the wish so common among frail, elderly people: to die at home. But it seemed as if all the forces of the health care system were against her -; hospitals, nursing homes, home health agencies, insurance companies, and the shifting crosscurrents of public health care spending (Nina Bernstein, 9/25).

3 Oct 2014

Research offers hope to patient suffering from Duchenne muscular dystrophy

Research at Stockholm's KTH Royal Institute of Technology offers hope to those who suffer from Duchenne muscular dystrophy, an incurable, debilitating disease that cuts young lives short.

21 Aug 2014

Researchers take major step forward in understanding causes of CRPS

Researchers at the University of Liverpool have taken a major step forward in understanding the causes of a disorder which causes chronic pain in sufferers.

2 Jul 2014

Isis Pharmaceuticals begins ISIS-DMPK Rx Phase 1 study for treatment of Myotonic Dystrophy Type 1

Isis Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 study for ISIS-DMPKRx. Isis earned a $14 million milestone payment from Biogen Idec associated with this achievement.

9 Jun 2014

Sildenafil may help boys suffering from muscular dystrophy disease

Drugs used to treat erectile dysfunction may be able to slow disease progression in boys who suffer from the muscle wasting disease Duchenne muscular dystrophy.

8 May 2014

IRB Barcelona scientists develop new drug target to prevent muscle deterioration in certain diseases

In the study published today in the Journal of Clinical Investigation (JCI), one of the journals with highest impact in experimental medicine, the researchers associate the activity of the DOR protein with muscle atrophy and point to DOR as a plausible target against which to develop a drug to prevent muscle deterioration in certain diseases.

10 Apr 2014

Natural compound from green tomatoes protects against muscle atrophy

Using a screening method that previously identified a compound in apple peel as a muscle-boosting agent, a team of University of Iowa scientists has now discovered that tomatidine, a compound from green tomatoes, is even more potent for building muscle and protecting against muscle atrophy.

10 Apr 2014

Scientists honored for orthopedic breakthroughs at 2014 AAOS Annual Meeting

The Kappa Delta Sorority and the Orthopaedic Research and Education Foundation presented four research awards today to scientists who are performing research that translates to improvements in patient treatment and care.

13 Mar 2014

Prothelia and University of Nevada, Reno enter into agreements with Alexion for development of Laminin-111

Prothelia Incorporated (Prothelia) and University of Nevada, Reno announce that they have entered into strategic agreements with Alexion for the development of Laminin-111, a patented experimental protein replacement therapy for merosin-deficient congenital muscular dystrophy (MDC1A), a life-threatening, ultra-rare disease caused by a genetic deficiency of the Laminin-211 protein.

26 Feb 2014

New therapeutic target may help repair muscle damage

Researchers at the Stanford University School of Medicine have pinpointed why normal aging is accompanied by a diminished ability to regain strength and mobility after muscle injury: Over time, stem cells within muscle tissues dedicated to repairing damage become less able to generate new muscle fibers and struggle to self-renew.

18 Feb 2014

Prothelia, University of Nevada, Reno and Alexion partner to develop Laminin-111 for MDC1A

Prothelia Incorporated and University of Nevada, Reno announce that they have entered into strategic agreements with Alexion for the development of Laminin-111, a patented experimental protein replacement therapy for merosin-deficient congenital muscular dystrophy (MDC1A), a life-threatening, ultra-rare disease caused by a genetic deficiency of the Laminin-211 protein.

13 Feb 2014

New orthotic device could aid in rehabilitation of patients with ankle-foot disorders

A soft, wearable device that mimics the muscles, tendons and ligaments of the lower leg could aid in the rehabilitation of patients with ankle-foot disorders such as drop foot, said Yong-Lae Park, an assistant professor of robotics at Carnegie Mellon University.

22 Jan 2014

University of Barcelona participates in ‘Astronaut Exercise Prescriptions Promoting Health and Fitness on Earth’ project

The University of Barcelona participates in the European project A-fit (Astronaut Exercise Prescriptions Promoting Health and Fitness on Earth), coordinated by the Karolinska Institute (Sweden). It aims at designing a fitness programme to avoid muscle atrophy associated to microgravity. Its results will contribute to the understanding of the beneficial effects of exercise in order to combat the effects of long-term muscle disuse. Findings may be also applied to other research areas, for instance, those diseases characterized by muscular dysfunction.

28 Dec 2013