Muscle Deterioration News and Research

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Brown grants exclusive intellectual property license to Tivorsan Pharmaceuticals

Development of a potential treatment for the most common form of muscular dystrophy is moving into a new phase at Brown University. Brown has granted an exclusive license for the intellectual property to Tivorsan Pharmaceuticals, a startup firm that will strive to see it through human trials.

22 Sep 2010

Sticky protein protects cells from mechanical stress

A new study by scientists at the University of Iowa shows why muscle membranes don't rupture when healthy people exercise.

26 Jul 2009

Progressive resistance strength training for improving physical function in seniors

Progressive resistance strength training not only helps older adults become stronger but also makes their everyday life easier, a Cochrane Review suggests.

7 Jul 2009

Muscle damage may be present in some patients taking statins

Structural muscle damage may be present in patients who have statin-associated muscle complaints, found a new study in CMAJ (Canadian Medical Association Journal).

7 Jul 2009

New drug for muscle degenerating diseases shows great promise

A new drug being studied for the treatment of muscle degenerating diseases has shown promising results. According to a study published today in the British Journal of Pharmacology, Debio 025 is as effective as current drugs but, crucially, does not cause unwanted immunosuppressive effects.

10 Jun 2009

Scientists cure mice of muscle disease that causes a Floppy Baby Syndrome

In a world first, West Australian scientists have cured mice of a devastating muscle disease that causes a Floppy Baby Syndrome - a breakthrough that could ultimately help thousands of families across the globe.

25 May 2009

Muscle deterioration in patients with lung disease connected to high carbon dioxide levels in blood

Muscle deterioration in patients with lung diseases might be a direct consequence of high carbon dioxide levels in their blood, an international team of researchers headed by Prof. Yosef Gruenbaum of the Hebrew University of Jerusalem has found.

23 Apr 2009

Rockefeller University Hospital opens clinical trial into statin-associated muscle complaints

The most widely prescribed class of drugs in the country, statins have helped millions of people lower their cholesterol and reduce their risk of heart attacks - but their side effects, including muscle pain and cramping, have proven to be something of a sore point for many patients.

14 Apr 2009

First treatment for muscular dystrophy a step closer

Genetic researchers at Children's National Medical Center and the National Center of Neurology and Psychiatry in Tokyo published the results of the first successful application of "multiple exon-skipping" to curb the devastating effects of Duchenne muscular dystrophy in an animal larger than a mouse.

16 Mar 2009

Novel genetic technology for canine form of muscular dystrophy

Using a novel genetic technology that covers up genetic errors, researchers funded in part by the National Institutes of Health have developed a successful treatment for dogs with the canine version of Duchenne muscular dystrophy, a paralyzing, and ultimately fatal, muscle disease.

16 Mar 2009

Carbon monoxide counteracts one side-effect of an anti-cancer drug

Doxorubicin (DOX) is a red-colored anticancer drug that carries serious side effects for the heart, including cardiac muscle deterioration (cardiomyopathy) and scar tissue accumulation in the heart (fibrosis).

21 Nov 2007

New target for muscular dystrophy drug therapy

Researchers at the University of Pennsylvania School of Medicine report how the gene for utrophin, which codes for a protein very similar to dystrophin, the defective protein in Duchenne muscular dystrophy (DMD), puts the brakes on its own expression in muscle cells, thereby suggesting a new target for treatment.

13 Jul 2007

Extended bed rest leads to substantial muscle deterioration in older adults

Extended bed rest – often necessary during hospitalization – leads to a substantial amount of muscle deterioration in older adults, researchers at the University of Arkansas for Medical Sciences (UAMS) report in the April 25 issue of the Journal of the American Medical Association .

25 Apr 2007

Most serious side effects in statins may be higher in one of the newest drugs, rosuvastatin (Crestor)

A post-market analysis of cholesterol-lowering drugs called statins indicates that some of the most serious side effects may be higher in one of the newest drugs, rosuvastatin (Crestor). The drug is the strongest statin available because it has the greatest effect per milligram on low-density lipoprotein ("bad" cholesterol).

26 May 2005

Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy

Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy and can be offered as a treatment option, according to the American Academy of Neurology and the Child Neurology Society in a new practice guideline published in the January 11 issue of Neurology, the scientific journal of the American Academy of Neurology.

10 Jan 2005

Study looks at muscle repair and resilience

Healthy military personnel and muscular dystrophy patients are at opposite ends of the spectrum when is comes to muscle strength and resilience. However, a new University of Iowa study may provide insights that improve muscle health for both these groups.

7 Dec 2004

Australian cricketers have had their muscles scanned by researchers to prevent muscle deterioration and injury

The 24-man-squad from Cricket Australia’s Centre of Excellence in Brisbane, were examined by University of Queensland’s senior physiotherapy lecturer Dr Julie Hides.

27 May 2004