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Myelin is the fatty substance that covers and protects nerves.

New adaptive clinical trial aims to reverse neurological damage caused by progressive multiple sclerosis

The first-ever adaptive clinical trial for Australians living with MS will seek to reverse neurological damage caused by progressive multiple sclerosis.

4 Dec 2023

Abnormal myelin, not loss of myelin, may drive axon degeneration in myelin diseases

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins.

28 Nov 2023

Researchers take step toward developing cell therapy treatment for MS

An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.

27 Nov 2023

Nutrition and aging: A two-way relationship

With so much hype in the media about miracle diets and nutritional supplements, one is invariably tempted to look for a single, food-based magic bullet that will increase the likelihood of living a longer, healthier life.

3 Nov 2023

Cancer neuroscience: A new frontier in cancer treatment

Cancer cells hijack normal biological processes, allowing them to multiply. For example, tumors spur construction of new blood vessels, building themselves "highways" to supply nutrients.

1 Nov 2023

Dementia and cholesterol: investigating links and impacts of hormone replacement therapy

The relationships between hormone replacement therapy (HRT), serum cholesterol levels, and dementia incidence.

25 Oct 2023

New software uncovers that myelin develops much slower after birth

A single brain is unfathomably complex. So brain researchers, whether they're looking at datasets built from 300,000 neurons in 81 mice or from MRIs of 1,200 young adults, are now dealing with so much information that they must also come up with new methods to comprehend it.

22 Sep 2023

N-acetylglucosamine reduces multiple inflammation and neurodegeneration markers in MS patients

UCI researchers have found that a simple sugar, N-acetylglucosamine, reduces multiple inflammation and neurodegeneration markers in people who suffer from multiple sclerosis (MS).

14 Sep 2023

MRI innovation to unveil iron homeostasis in the human brain

Researchers demonstrated a MRI method sensitive to the live brain's iron homeostasis (the r1-r2 extent of relaxation or relaxivity).

14 Sep 2023

“Inverse vaccine” shows promise to reverse autoimmune diseases without shutting down rest of the immune system

A new type of vaccine developed by researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) has shown in the lab setting that it can completely reverse autoimmune diseases like multiple sclerosis, type 1 diabetes, and Crohn's disease -; all without shutting down the rest of the immune system.

12 Sep 2023

OHSU scientists discover new avenue of cell death in Alzheimer's disease and vascular dementia

Researchers have discovered a new avenue of cell death in Alzheimer's disease and vascular dementia.

5 Sep 2023

AI-driven analysis of MRI scans could pave the way for improved multiple sclerosis treatment

New research exploring cutting-edge Artificial Intelligence (AI) technology to better analyse MRI scans of patients with multiple sclerosis (MS) could unlock crucial insights into disease progression and pave the way for improved treatment of people living with the condition.

4 Sep 2023

Researchers discover new biological mechanism to regenerate and repair myelin

A study led by Dr. Hyun Kyoung Lee, associate professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a new biological mechanism to regenerate and repair myelin, a protective sheath that insulates neuronal fibers and plays a vital role in ensuring rapid and accurate neurotransmission.

24 Aug 2023

Study provides insight into aging of the brain

Most of us who've reached middle age have noticed a slowing in memory and cognition, but scientists don't have a clear picture of the molecular changes that take place in the brain to cause it.

17 Aug 2023

The role of self-extracellular nucleic acids in neuroinflammation

Researchers explore the role of self-extracellular nucleic acids in diseases like stroke, multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease.

14 Aug 2023

Researchers discover possible new biomarker of MS-like autoimmune disease

It has been known for several years that the diagnosis "multiple sclerosis" conceals a whole range of different illnesses, each requiring customized treatment. Researchers at the University of Basel and the University Hospital of Basel have now described a possible new MS-like disease and explained how to diagnose it.

8 Aug 2023

How does the circulating proteome influence brain health?

Researchers investigate the association between the circulating proteome and brain health.

7 Aug 2023

Can vitamin D have positive effects on reducing cortical pathology, oxidative stress, and neurofilament light chain serum levels?

Researchers use an established murine model of cortical inflammatory demyelination to investigate the effects of vitamin D.

2 Aug 2023

Early treatment for multiple sclerosis linked to lower disability risk

People who start taking medication soon after the first signs of multiple sclerosis (MS) may have a lower risk of disability later, according to a study published in the July 19, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Jul 2023

Magnetic susceptibility as a promising marker for predicting future severity of Parkinson's disease

Researchers evaluate quantitative magnetic susceptibility mapping in detecting quantifiable markers of Parkinson’s disease progression.

18 Jul 2023