Myopathy News and Research

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The myopathies are neuromuscular disorders in which the primary symptom is muscle weakness due to dysfunction of muscle fiber. Other symptoms of myopathy can include include muscle cramps, stiffness, and spasm. Myopathies can be inherited (such as the muscular dystrophies) or acquired (such as common muscle cramps).

The health status and exercise capacity of COVID-19 survivors one year after hospital discharge

A recent study evaluated the health status and exercise capacity of COVID-19-recovered patients one year after hospital discharge.

13 Oct 2022

The effects and mechanisms of SARS-CoV-2 on the nervous system

Researchers reviewed the neurologic manifestations associated with SARS-CoV-2.

30 Jun 2022

Simplicity is key when it comes to ablation, global AFib study finds

Results from one of the largest global studies of atrial fibrillation (AFib) procedures show that the simple approach is usually best when it comes to ablation, a procedure where physicians destroy or ablate cardiac tissue to correct irregular heart rhythms.

21 Jun 2022

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

A new study by researchers at Hospital for Special Surgery (HSS) has further clarified the clinical manifestations of undifferentiated connective tissue disease (UCTD).

2 Jun 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

Researchers present a possible therapeutic approach for severe congenital myopathy

The diagnosis is rare, but devastating – children with congenital muscle disorders often never learn to walk. Until now, there was no chance of recovery, but researchers at the University of Basel and University Hospital Basel are now presenting a possible therapeutic approach for the first time.

29 Mar 2022

Visual ultrasound of the heart helps identify novel measures linked to a higher dementia risk

Published in JAMA, research from the University of Minnesota assessed if there is a link between heart health and dementia.

23 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Study helps understand actionable genetic variation affecting drugs in the Middle East population

A group of researchers at Qatar Foundation have reported the first comprehensive study of the distribution of actionable genetic variation affecting drugs in any Middle Eastern population, with potential implications for preemptive pharmacogenomic implementation in the region.

16 Feb 2022

Looking into the long-COVID brain

Neurological issues, ranging from memory lapses to trouble with attention, have been widely reported after recovery from severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection. Unfortunately, there is limited information about pathways to recovery after severe COVID hospitalization. Now, a prospective study of 4,491 patients hospitalized with COVID suggests neurological recovery can take at least a year. The study is currently available on the medRxiv* preprint while awaiting peer review.

13 Feb 2022

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.

19 Jan 2022

A case of post-vaccination MIS in an adult without prior SARS-CoV-2 infection

A new case study on the report of multisystem inflammatory syndrome (MISC) in a 22-year-old woman in South Korea after vaccination.

5 Dec 2021

Peripheral nerve injuries and severe COVID-19

An interesting new study discusses the occurrence of peripheral nerve injuries in a subset of patients who survived severe COVID-19.

29 Sep 2021

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure.

9 Sep 2021

CHOP researchers develop tool to monitor disease severity in patients with mitochondrial myopathy

Researchers at Children's Hospital of Philadelphia successfully developed and validated a new outcome measure to monitor disease severity and progression in patients with impaired skeletal muscle function caused by mitochondrial disease.

1 Sep 2021

Cows can pass on hypoglycin A toxin through their milk, shows study

Cows can pass on the hypoglycin A toxin through their milk, a study by the Martin Luther University Halle-Wittenberg (MLU) and the Leibniz Institute of Plant Biochemistry (IPB) in Toxins shows. The substance can cause severe symptoms in humans and animals.

8 Jun 2021

What is the role of nanotechnology in the current COVID-19 outbreak?

The nanotechnology-based medicine platforms against COVID-19 bears hope for relief from the pandemic to save lives and mitigate the infection as part of a broader global public health agenda.

27 Apr 2021

Researchers identify mechanism by which dermatomyositis may develop in humans

Dermatomyositis is an idiopathic inflammatory myopathy that has been regarded as an autoimmunity-based disorder, although its pathogenesis remains unclear.

8 Apr 2021

How SARS-CoV-2 enters the central nervous system

The central nervous system (CNS) is highly protected in the human body. Yet, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the CNS, causing profound clinical complications. How is the CNS involved in a respiratory virus infection?

15 Feb 2021