Necrosis News and Research

RSS

SyNAPSe® Trial by BHR Pharma deemed to have no safety issues according to DSMB

BHR Pharma, LLC announced today that the SyNAPSe® Trial's independent Data and Safety Monitoring Board (DSMB) evaluated safety data from 803 randomized patients and determined that no issues exist; therefore, the trial may continue towards its intended completion.

17 Jan 2013

Brake for skin inflammation discovered

The absence of a protein called Ctip2 in the skin allows increased levels of T-helper 2 cytokines and may have a role in conditions such as atopic dermatitis, research in mice suggests.

4 Jan 2013

Pediatric caustic ingestion injuries ‘much lower than believed’

The public health burden associated with children swallowing caustic chemicals is less than widely believed, US researchers report in the Archives of Otolaryngology - Head and Neck Surgery.

2 Jan 2013

TNF inhibitor efficacy may depend on brain activity

How well a patient responds to tumor necrosis factor inhibitor therapy may depend on brain activity reflecting the individual’s perception of their rheumatoid arthritis, scientists believe.

24 Dec 2012

Perthes’ disease link to congenital disorders revealed

Researchers have linked Perthes' disease with several congenital conditions, pointing to intra-uterine factors behind the development of the disease.

14 Dec 2012

Ultra-shortened, accelerated breast irradiation treatment logistically achievable and tolerable

Research from The Cancer Institute of New Jersey shows that an ultra-shortened, accelerated breast irradiation treatment using a balloon device is both logistically achievable and tolerable. The work will be offered during a poster presentation at the 35th Annual CTRC-AACR San Antonio Breast Cancer Symposium this week. The Cancer Institute of New Jersey is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School (RWJMS).

7 Dec 2012

Dietary fish oil supplements could help heal bedsores

Chock-full of Omega-3 fatty acids and antioxidants, fish oil can help lower blood pressure, reduce inflammation in the skin and joints, and promote healthy fetal development. Now a Tel Aviv University researcher has found that it has a positive effect on bedsores, too.

5 Dec 2012

Inflammatory marker targeted in ear infection

Systemic injection of an antibody against granulocyte/macrophage colony-stimulating factor inhibits middle-ear inflammation induced by lipopolysaccharide in mice, study findings show.

3 Dec 2012

Study examines role of inflammation in chronic fatigue syndrome

A new study published in the current issue of Psychotherapy and Psychosomatics has examined the role of inflammation in chronic fatigue syndrome, a disorder that affects many people and does not seem to have an explanation that is likely to yield satisfactory treatment.

1 Dec 2012

New paper describes MCUR1 protein and its function

Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell's energy storehouse - the mitochondria -- is important for understanding a cell's normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

29 Nov 2012

Overexpressed enzyme contributes to development of preeclampsia

Preeclampsia is a serious complication of pregnancy and the major cause of death for both mother and child in Europe and the U.S. It affects about one in 20 pregnancies. The main symptoms are high blood pressure and protein in the urine.

26 Nov 2012

Rheumatoid arthritis patients adhere to both adalimumab, etanercept

Patients with active rheumatoid arthritis are as likely to persist with adalimumab treatment as they are with etanercept, show the results of a 2-year randomized efficacy and discontinuation study of the two tumor necrosis factor inhibitors.

23 Nov 2012

Modified breast reduction technique noninferior to traditional

Modifying the inferior pedicle technique of breast reduction results in outcomes that are at least comparable to, and perhaps better than, those previously reported, researchers say.

22 Nov 2012

Treatment-related heart failure risk for rheumatoid arthritis patients revealed

Rheumatoid arthritis patients have no greater risk for heart failure with tumor necrosis factor-alpha therapy than with nonbiologic disease-modifying antirheumatic drugs, research suggests.

19 Nov 2012

Two equally effective TNF inhibitors in rheumatoid arthritis

Adalimumab and etanercept are equally effective as tumor necrosis factor inhibitors in the treatment of patients with active rheumatoid arthritis, report researchers.

19 Nov 2012

New gene delivery vehicle opens route to the heart of cells in solid tumors

There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.

15 Nov 2012

Drug trio may reduce eliminate cardiac side effects of doxorubicin

Combining cancer medication with a drug for erectile dysfunction and one for heart transplants helped kill cancer cells and protected the heart from damage, in a study presented at the American Heart Association's Scientific Sessions 2012.

7 Nov 2012

Anti-TNF-α therapy reduces CVD risk in patients with rheumatoid arthritis

Patients with rheumatoid arthritis exhibit a sub-clinical vasculitis that may underlie their increased risk for cardiovascular disease, shows research.

5 Nov 2012

Partial dentin removal superior to stepwise excavation over long term

Partial caries removal treatment for individuals with deep caries lesions results in significantly improved pulp vitality after 3 years than does stepwise excavation, indicate Brazilian study findings.

1 Nov 2012