Neglected Tropical Disease News and Research

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Research may pave the way for designing new therapies to combat schistosomiasis

Neglected tropical diseases (NTDs) represent a group of about 20 conditions that affect more than a billion people worldwide.

6 Jan 2022

A nematode infection can become severe and deadly with the use of corticosteroids

Healthcare workers in tropical and sub-tropical settings where strongyloidiasis is prevalent or caring for patients who have travelled to such areas, need to maintain a high level of awareness about the use of corticosteroids, including when this class of anti-inflammatories is given to patients suspected of infection with SARS-CoV-2.

19 Dec 2021

Neuropharmacologist investigates plant-based treatments for epilepsy caused by pork tapeworms

Pork tapeworms are responsible for between 30 and 70 per cent of epilepsy cases around the world. According to the World Health Organization, the majority of people living with epilepsy can be found in low-income countries, mostly among subsistence farming communities.

19 Nov 2021

New resolution urges Member States to focus on prevention and management of diabetes, obesity

A new resolution urges Member States to raise the priority given to the prevention, diagnosis and control of diabetes as well as prevention and management of risk factors such as obesity.

29 May 2021

Infrared thermal imaging camera can help monitor the progression of lymphatic filariasis

A paper published in the Journal of Clinical Medicine presents the results from a study which examined the use of an infrared thermal imaging camera as a novel non-invasive point-of-care tool for lymphatic filariasis lower-limb lymphoedema.

26 May 2021

Scientists to use CRISPR gene-editing technology for Phase 1 vaccine trials in humans

Scientists are planning for Phase 1 human trials of a vaccine they developed by using CRISPR gene-editing technology to mutate the parasite that causes leishmaniasis, a skin disease common in tropical regions of the world and gaining ground in the United States

25 Sep 2020

Showers, toilets and washbasins may act as SARS-CoV-2 reservoirs despite low environmental transmission

In their new research paper currently available on the medRxiv* preprint server, scientists from the University of Bonn in Germany demonstrated that indirect environmental transmission most likely plays only a minor role in the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, certain potentially neglected viral reservoirs have to be taken into account when introducing epidemiological measures.

3 Jun 2020

Venatorx and GARDP collaborate to accelerate development of new antibiotic

Venatorx Pharmaceuticals and the Global Antibiotic Research and Development Partnership (GARDP) today announced a collaboration to accelerate the development of, and access to, cefepime-taniborbactam (formerly cefepime/VNRX-5133).

29 Apr 2020

Global funding for neglected disease research reaches a record high

For the first time, global funding for neglected disease R&D grew for three consecutive years, reaching a record high of more than US$4.05 billion in 2018.

30 Jan 2020

International consortium to receive BRL 43.5 million for discovering drugs to treat neglected diseases

In the search for new drugs to treat neglected diseases and malaria, researchers at the University of Campinas and University of Sao Paulo will assemble a team of scientists in a global collaboration network co-funded by the São Paulo Research Foundation, the Drugs for Neglected Diseases initiative and the Medicines for Malaria Venture.

26 Nov 2019

Otago researchers join vaccine research project to tackle Salmonella bloodstream infections in Africa

A team of University of Otago researchers is part of a major new international vaccine research project to help tackle devastating Salmonella bloodstream infections which are killing thousands of people in sub-Saharan Africa each year.

1 Nov 2019

Johns Hopkins researchers estimate real-world prevalence of prurigo nodularis

Johns Hopkins researchers report that prurigo nodularis, a skin disease characterized by severely itchy, firm bumps on the skin, may be associated with other inflammatory skin disorders as well as systemic and mental health disorders.

From Johns Hopkins Medicine 26 Aug 2019

Scientists study immune molecules inside mycetoma grains

Mycetoma is a common neglected disease caused by either fungi or bacteria which organize themselves into grains—areas of inflammation surrounded by a collagen capsule.

From PLOS ONE 12 Jul 2019

UGR scientists break new ground in Chagas disease research

A team of scientists from the University of Granada has broken new ground in Chagas disease research.

10 May 2019

United Nations sounds alarm bell on drug-resistant infections

According to a new report from a United Nations Committee, antibiotic resistance levels are at an all time high and are the reason behind common infections becoming difficult to treat.

30 Apr 2019

GARDP forms multi-actor partnerships to discover new antibiotics

Multi-actor partnership tests natural products and compound libraries for antibacterial activity Discovery efforts will focus on World Health Organization's priority pathogens The Global Antibiotic Research and Development Partnership is partnering with Calibr, the Helmholtz Centre for Infection Research, in particular its location Helmholtz-Institute for Pharmaceutical Research Saarland, and the University of Queensland's Community for Open Antimicrobial Drug Discovery in its efforts to develop and ensure new antibiotics are globally available to all patients who need them.

11 Apr 2019

New survey indicates need of attention to neglected tropical diseases

Although neglected diseases account for 11% of the global disease burden, they are targeted by only a small proportion of the new drugs developed every year.

22 Mar 2019

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

The Global Antibiotic Research and Development Partnership and Evotec AG are today announcing the formation of a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance.

19 Mar 2019

Shorter treatment for Chagas disease found to be effective and safer than standard treatment

A two-week treatment course for adult patients with chronic Chagas disease showed, when compared to placebo, similar efficacy and significantly fewer side effects than the standard treatment duration of eight weeks, according to the results of a clinical trial in Bolivia led by the Drugs for Neglected Diseases initiative.

14 Mar 2019

GARDP and Penta join forces to deal with drug-resistant infections in children

The Global Antibiotic Research & Development Partnership and Penta, the pediatric infectious diseases research network, have joined forces to tackle drug-resistant infections in children.

5 Mar 2019