Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Critical Path Institute announced today that a formal consultation between its Predictive Safety Testing Consortium and Japan's Pharmaceuticals and Medical Devices Agency has resulted in an agreement on a first-of-its-kind approach to compare the levels of eight novel urinary kidney safety biomarkers in healthy Japanese volunteers to data collected on these same biomarkers in healthy Western volunteers in a bridging study.

27 Mar 2019

Causes of diabetes decline or disappear when ‘zombie cells’ are removed, shows study

Mayo Clinic researchers and their collaborators have shown that when senescent cells -- also known as "zombie cells" -- are removed from fat tissue in obese mice, severity of diabetes and a range of its causes or consequences decline or disappear. The findings appear in Aging Cell.

26 Mar 2019

New molecular mechanism involved in pancreas repair identified

Ramón Muñoz-Chápuli and Rita Carmona, researchers of the UMA Department of Animal Biology, have identified a new molecular mechanism involved in pancreas repair.

25 Mar 2019

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

25 Mar 2019

Bisphosphonates to treat osteoporosis appears to be beneficial for all women

In recent years, women who start taking bisphosphonates to treat osteoporosis and prevent fracture have trended from younger to older and from having osteopenia to having osteoporosis, researchers report.

25 Mar 2019

New guideline focuses on strategies to improve health of older adults with diabetes

Simplifying medication regimens and tailoring glycemic targets in older adults with diabetes improves adherence and avoids treatment-related complications, according to a Clinical Practice Guideline issued today by the Endocrine Society.

25 Mar 2019

Hemoglobin A1c blood test does not detect diabetes in most patients, shows study

The hemoglobin A1c blood test is widely used to diagnose type 1 and type 2 diabetes, but it is actually unable to detect the disease in most patients, according to a new study presented Saturday, March 23, at a news conference at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Repurposing drugs to outsmart cancers

In an article published today by SAGE Publishing, investigators from The Nagourney Cancer Institute and The Albert Einstein Israelite Hospital in São Paulo, Brazil, announced a new approach to identifying effective treatments for patients with advanced metastatic cancers. A drug commonly used to treat kidney and liver cancer was discovered effective for breast cancer, which may open new drug therapies to patients regardless of tumor type.

22 Mar 2019

Researchers identify a more effective treatment for cancer

Researchers from Mount Sinai and IBM have discovered a novel clue in explaining how cancer cells with identical genomes can respond differently to the same therapy.

22 Mar 2019

Did your doctor ‘ghost’ you? An employment contract may be to blame

When Don Cue developed a bladder infection last fall, he called his longtime urologist's office for a urine culture and antibiotics. It was a familiar routine for the two-time prostate cancer survivor; infections were not uncommon since he began using a catheter that connects to his bladder through an incision in his abdomen.

19 Mar 2019

Common medications to treat heartburn linked to increased risks for kidney failure

Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study.

19 Mar 2019

Study sheds light on the optimal timing of coronary angiography in NSTEMI patients

In patients resuscitated after cardiac arrest who do not show evidence of the type of heart attack known as ST-segment elevation myocardial infarction (STEMI), receiving immediate coronary angiography did not improve survival at 90 days compared to waiting a few days before undergoing the procedure, based on findings presented at the American College of Cardiology's 68thAnnual Scientific Session.

19 Mar 2019

Less invasive valve replacement can be safe and effective alternative for healthier patients

A new study by a team of cardiologists at Beth Israel Deaconess Medical Center led by senior and corresponding author Jeffrey Popma, MD, suggests that a minimally invasive procedure currently reserved for patients too frail to undergo surgery may in fact be a safe and effective alternative for healthier patients.

19 Mar 2019

Two-drug combinations containing calcium channel blocker significantly lowers BP

In the largest randomized controlled trial of treatment for high blood pressure ever conducted in sub-Saharan Africa, two frontline two-drug combinations that included the long-acting calcium channel blocker, amlodipine, were able to drive down blood pressure levels more than a third two-drug combination that did not include amlodipine, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.

19 Mar 2019

One-off surgery could offer hope to patients with high blood pressure

A one-off operation that targets the nerves connected to the kidney has been found to maintain reduced blood pressure in hypertension patients for at least six months, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research.

18 Mar 2019

Preventative cardioverter defibrillator implantation is of little benefit to kidney dialysis patients

Placing an implantable cardioverter defibrillator in kidney dialysis patients as a preventative measure is of little benefit.

18 Mar 2019

Study highlights the need for psychiatric care to be integrated into cancer treatment

Patients with prostate, bladder or kidney cancers are at greater risk of dying if they have had psychiatric care prior to the cancer treatment. In addition, patients with these cancers show greater suicide risk than the general population, even once the data is corrected for previous psychiatric care.

18 Mar 2019

Study finds TAVR to be as good as open-heart surgery for patients at low surgical risk

A new trial comparing self-expanding transcatheter aortic valve replacement (TAVR) to standard open-heart surgery for valve replacement—this time in patients with severe aortic stenosis who are considered low surgical risk—found no difference in the combined rate of disabling stroke or death from any cause at two years.

18 Mar 2019

Sweat shows promise for noninvasive health monitoring

Making a revolutionary biosensor takes blood, sweat and tears. And saliva, naturally.

15 Mar 2019

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved mechanisms to detoxify and expel damaging substances.

15 Mar 2019

Nephrology News and Research

Further Reading

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Causes of diabetes decline or disappear when ‘zombie cells’ are removed, shows study

New molecular mechanism involved in pancreas repair identified

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

Bisphosphonates to treat osteoporosis appears to be beneficial for all women

New guideline focuses on strategies to improve health of older adults with diabetes

Hemoglobin A1c blood test does not detect diabetes in most patients, shows study

Repurposing drugs to outsmart cancers

Researchers identify a more effective treatment for cancer

Did your doctor ‘ghost’ you? An employment contract may be to blame

Common medications to treat heartburn linked to increased risks for kidney failure

Study sheds light on the optimal timing of coronary angiography in NSTEMI patients

Less invasive valve replacement can be safe and effective alternative for healthier patients

Two-drug combinations containing calcium channel blocker significantly lowers BP

One-off surgery could offer hope to patients with high blood pressure

Preventative cardioverter defibrillator implantation is of little benefit to kidney dialysis patients

Study highlights the need for psychiatric care to be integrated into cancer treatment

Study finds TAVR to be as good as open-heart surgery for patients at low surgical risk

Sweat shows promise for noninvasive health monitoring

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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