Neural Stem Cells News and Research

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Researchers identify earliest neuron in the embryonic human cerebral cortex

Researchers at Yale School of Medicine and the University of Oxford have identified the very first neurons in what develops into the cerebral cortex, the part of the brain that makes humans human.

24 Jul 2006

Scientists use embryonic stem cells to awaken latent motor nerve repair

In a dramatic display of stem cells' potential for healing, a team of Johns Hopkins scientists reports that they've engineered new, completed, fully-working motor neuron circuits - neurons stretching from spinal cord to target muscles - in paralyzed adult animals.

26 Jun 2006

New roles for growth factors

During embryonic development, nerve cells hesitantly extend tentacle-like protrusions called axons that sniff their way through a labyrinth of attractive and repulsive chemical cues that guide them to their target.

18 Jun 2006

German scientists synthesize new compound that reduces stroke damage

A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.

16 May 2006

SOX2 neural stem cell gene important in eye development

Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place.

16 May 2006

Stem cells can repair damaged spinal tissue and help restore function in rats with spinal cord injuries

Each year, some 11,000 Americans sustain spinal cord injury, most often in traffic accidents. Costs of the condition approach $10 billion per year.

11 Apr 2006

Cell therapy slows progression of metachromatic leukodystrophy

In an important discovery, scientists have demonstrated that the progression of a type of genetic brain disease is slowed and symptoms are improved in mice that received cell transplants.

23 Mar 2006

Scientists have gained valuable new insight into the biology of aggressive, incurable brain tumors

A research study published in the March issue of Cancer Cell uses gene expression profiling to identify molecular profiles and signaling pathways associated with tumor aggressiveness and disease progression.

15 Mar 2006

Trial explores safety and efficacy of injecting human stem cells directly into the brain to treat fatal pediatric neurodegenerative disorder

Researchers in Doernbecher Children's Hospital at Oregon Health & Science University will begin a Phase I clinical trial using stem cells in infants and children with a rare neurodegenerative disorder that affects infants and children.

13 Mar 2006

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return.

1 Mar 2006

Scientists find key step in a signaling pathway that helps orchestrate embryonic development

The study, reported in Nature (Oct. 13, 2005), focuses on the Hedgehog family of signaling molecules, which play a central role in directing development of the early embryo's growth and spatial plan, as well as its later organ and limb development. Defects in Hedgehog signaling are a significant cause of some birth defects and cancers.

25 Oct 2005

FDA approves first transplant of fetal stem cells into human brains

The U.S. Food and Drug Administration has approved the first transplant of fetal stem cells into human brains, a procedure that if successful could pave the way to treating a host of neural disorders.

24 Oct 2005

Immature stem cells that proliferate to form brain tissues in mice can function for at least a year

New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year -- most of the life span of a mouse -- and give rise to multiple types of neural cells, not just neurons.

5 Oct 2005

Stem cells may unlock the secrets to healing the brain

These amazing cells have the remarkable potential to develop into many different cell types in the body and have to potential to revolutionise medical science.

27 Sep 2005

Adult human neural stem cells used to successfully regenerate spinal cord tissue

Researchers at the UC Irvine Reeve-Irvine Research Center have used adult human neural stem cells to successfully regenerate damaged spinal cord tissue and improve mobility in mice.

26 Sep 2005

Workshop - stem cells in reproduction and in the brain

"Once we have found the factors by which body cells can be re-programmed into stem cells, then therapeutic cloning might become superfluous," said Hans R. Scholer, director of the Max Planck Institute for Molecular Biomedicine in Munster, Germany, at an international scientific symposium on stem cell research in Kobe, Japan.

10 Sep 2005