Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Stem-cell-derived brain cells hold promise for Alzheimer's, Parkinson's research

Researchers at the University of Wisconsin–Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer's and Parkinson's diseases and used the discovery to grow the neurons from stem cells for the first time.

17 Nov 2023

Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

Study assesses the effectiveness of photobiomodulation (PBM) treatment in a mouse model of Alzheimer's disease and finds no significant impact on behavioral performance or neurodegeneration, suggesting the need for further research into PBM's therapeutic potential.

16 Nov 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Investigating the link between gut inflammation, aging, and Alzheimer's disease

A recent study in discusses how gut inflammation is associated with age and Alzheimer's disease.

15 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health

Neurodegenerative diseases like Alzheimer's and Parkinson's can be associated to depression and anxiety. Dr. Sabine Krabbe, a neuroscientist at DZNE's Bonn site, is receiving 1.2 million US dollars from the Chan Zuckerberg Initiative to understand the mechanisms involved in the onset of these syndromes.

10 Nov 2023

Unlocking secrets of aging: ENABL age offers detailed, individualized aging profiles using cutting-edge AI techniques

Combining machine learning with explainable artificial intelligence (XAI) to predict biological age with personalized explanations.

9 Nov 2023

Scientists unravel the mystery of how cells keep glutathione levels in check

If a delivery person leaves a package on your front step without pinging you, you likely won't know it's there.

8 Nov 2023

UC Riverside scientists slow progression of Huntington's disease in flies and worms

Huntington's disease causes involuntary movements and dementia, has no cure, and is fatal. For the first time, UC Riverside scientists have shown they can slow its progression in flies and worms, opening the door to human treatments.

8 Nov 2023

Researchers discover a new link between obesity and neurodegenerative disorders

Researchers led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center in the United States have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease.

7 Nov 2023

DZNE neuroscientist awarded 1.5 million euros to investigate biophysical phenomena relevant to brain diseases

Dr. Dragomir Milovanovic, a neuroscientist at DZNE's Berlin site, has been awarded an European Research Council (ERC) "Starting Grant" worth 1.5 million euros to investigate biophysical phenomena relevant to brain diseases in a groundbreaking research project.

7 Nov 2023

Gut health linked to Alzheimer's disease progression, experts urge dietary shift

The interactions between the gut microbiome, lipids, and Alzheimer’s disease (AD).

7 Nov 2023

Pandemic caused sustained cognitive decline in brain health in over 50s, study finds

Brain health in over 50s deteriorated more rapidly during the pandemic, even if they didn't have COVID-19, according to major new research linking the pandemic to sustained cognitive decline.

1 Nov 2023

New insights into role of cholinergic centro-cingulate network in Parkinson's disease and normal aging

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Cholinergic centro-cingulate network in Parkinson disease and normal aging."

1 Nov 2023

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Researchers investigated whether slow-wave sleep (SWS) proportions reduced as individuals aged and whether intra-individual decreases were linked to dementia risk.

1 Nov 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

Pilot Awards for Global Brain Health Leaders awarded to encourage innovative dementia research

Today, the Alzheimer's Association, Global Brain Health Institute (GBHI), and the UK-based Alzheimer's Society announced the most recent awardees of the Pilot Awards for Global Brain Health Leaders, a competitive funding initiative dedicated to nurturing efforts and improving outcomes in the fields of brain health and dementia.

31 Oct 2023

Brain autopsy study of intimate partner violence victims shows extensive brain damage

The largest brain autopsy study of women who had experienced intimate partner violence reveals substantial vascular and white matter damage in the brain, but no evidence of chronic traumatic encephalopathy (CTE), the neurodegenerative disease recognized among male contact sports athletes who sustain repeated head trauma.

30 Oct 2023

Enhancing deep sleep in older years could stave off dementia

As little as 1 per cent reduction in deep sleep per year for people over 60 years of age translates into a 27 per cent increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off dementia.

30 Oct 2023

Neurodegeneration News and Research

Further Reading

Stem-cell-derived brain cells hold promise for Alzheimer's, Parkinson's research

Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Investigating the link between gut inflammation, aging, and Alzheimer's disease

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health

Unlocking secrets of aging: ENABL age offers detailed, individualized aging profiles using cutting-edge AI techniques

Scientists unravel the mystery of how cells keep glutathione levels in check

UC Riverside scientists slow progression of Huntington's disease in flies and worms

Researchers discover a new link between obesity and neurodegenerative disorders

DZNE neuroscientist awarded 1.5 million euros to investigate biophysical phenomena relevant to brain diseases

Gut health linked to Alzheimer's disease progression, experts urge dietary shift

Pandemic caused sustained cognitive decline in brain health in over 50s, study finds

New insights into role of cholinergic centro-cingulate network in Parkinson's disease and normal aging

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

Pilot Awards for Global Brain Health Leaders awarded to encourage innovative dementia research

Brain autopsy study of intimate partner violence victims shows extensive brain damage

Enhancing deep sleep in older years could stave off dementia

Aneuro: A Year of Neuroscience in Review eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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