Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Elias family's gift to MD Anderson will help advance brain tumor and cancer neuroscience research

The University of Texas MD Anderson Cancer Center today announced a $16.25 million gift from Howard and Susan Elias to accelerate brain tumor and cancer neuroscience research, an emerging field focused on integrating the role of the nervous system in cancer.

18 Jul 2023

Magnetic susceptibility as a promising marker for predicting future severity of Parkinson's disease

Researchers evaluate quantitative magnetic susceptibility mapping in detecting quantifiable markers of Parkinson’s disease progression.

18 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

Superagers more likely to have greater movement speed than typical older adults

People in their eighties who can recall everyday events and life experiences as well as someone 20 to 30 years younger – known as superagers – are also more likely to have greater movement speed than typical older adults.

13 Jul 2023

Evotec and Bristol Myers Squibb enter licence agreement within neuroscience partnership

Evotec SE today announced that Bristol Myers Squibb Company has exercised its option to enter into an exclusive global licence agreement.

From Evotec 13 Jul 2023

Long-term high fluoride exposure during adolescence causes hippocampal impairments

Researchers evaluated the impacts of prolonged fluoride exposure during adolescence and adulthood on cognition and associated hippocampal alterations.

13 Jul 2023

New AI-aided biosensor developed to detect neurodegenerative diseases

By combining multiple advanced technologies into a single system, EPFL researchers have made a significant step forward in diagnosing neurodegenerative diseases (NDDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD).

12 Jul 2023

Scientists identify signal essential for blood-brain barrier formation

What makes the vital layer of protective cells around the brain and spinal cord -; the blood-brain barrier -; more or less permeable has been one of the more mystifying questions in neuroscience.

12 Jul 2023

Study provides unprecedented insights into the complexity of large-scale neural networks

That experiences leave their trace in the connectivity of the brain has been known for a while, but a pioneering study by researchers at the German Center for Neurodegenerative Diseases (DZNE) and TUD Dresden University of Technology now shows how massive these effects really are.

11 Jul 2023

Critical questions raised for evaluation of anti-amyloid immunotherapies in Alzheimer's treatment

Anti-amyloid immunotherapies for Alzheimer's disease require thorough evaluation of their efficacy, safety, and cost-effectiveness. Key questions regarding statistical analyses, treatment effects, and disease course modification guide evidence-based consideration of these drugs.

4 Jul 2023

Scientists use designer tubulins to crack the tubulin code

Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help the cell divide, give it its shape, and act as tracks for moving molecular cargo around inside the cell.

29 Jun 2023

University Hospital Bonn and DZNE receive prestigious "Ataxia Center of Excellence" award

The Ataxia Center at the University Hospital Bonn (UKB) and DZNE have been awarded the title "Ataxia Center of Excellence" by the US National Ataxia Foundation (NAF) for their patient care and research – as the only organization in Europe.

26 Jun 2023

Neurodevelopmental disruptions could pave the way for Alzheimer's disease

In the cerebral cortex, neurogenesis – the formation of neural cells from stem cells – begins in the fetus from 5 weeks gestation and is almost complete by 28 weeks.

16 Jun 2023

Gut microbiota holds clues to predicting Alzheimer's risk

Gut microbiome alterations in preclinical Alzheimer's disease (AD) were investigated, revealing distinct taxonomic composition and potential markers of AD risk. These findings contribute to understanding AD pathology and offer insights into gut-derived markers for AD.

15 Jun 2023

Transgenic mouse model reveals surprising new connections between peripheral nerves and the heart

Oxidative stress – characterized by elevated levels of unstable molecules called reactive oxygen species– is associated with neurodegeneration and cardiovascular disease.

14 Jun 2023

Study finds altered gut bacteria in people with early signs of Alzheimer's disease

People in the earliest stage of Alzheimer's disease -; after brain changes have begun but before cognitive symptoms become apparent -; harbor an assortment of bacteria in their intestines that differs from the gut bacteria of healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis.

14 Jun 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Bergamot fiber shows promise in battling neurodegenerative disorders

Bergamot fiber (BF), a byproduct of citrus fruit processing, shows antioxidant properties and protects against neurotoxicity induced by amyloid beta protein (Aβ), suggesting potential benefits for Alzheimer's disease treatment and waste reduction.

13 Jun 2023

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterised by an inability to repair skin damage caused by ultraviolet (UV) light.

11 Jun 2023

Study shows how blood makes the brain’s immune cells toxic

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive dysfunction and motor impairment.

8 Jun 2023