Neurodegenerative Disorder News and Research

RSS

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's.

27 Mar 2024

Groundbreaking study unveils new insights into neurodegenerative disorder symptoms

Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing.

14 Mar 2024

Study provides insights into the action and specificity of splice-modifying drugs

Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a process called RNA splicing.

6 Mar 2024

ChatGPT aids in discovering potential Alzheimer’s treatments through drug repurposing

ChatGPT-4 to identify drug repurposing candidates against Alzheimer’s disease (AD).

28 Feb 2024

Gender variations in brain aging among Parkinson's Disease patients

How sex influences brain aging in PD by analyzing MRI-derived brain age differences.

16 Feb 2024

Landmark study confirms five key Parkinson's Disease variants in largest meta-analysis

Rare Parkinson’s disease (PD) variants in a large-scale cohort.

10 Jan 2024

Photobiomodulation alleviates Aβ deposition and cognitive decline in mice with Alzheimer’s disease

Alzheimer's disease (AD) is an age-related neurodegenerative disorder. β-amyloid (Aβ) deposition in the brain is a crucial contributor to the pathogenesis of AD, mitigating excessive cerebral Aβ burden has been considered as a possible therapeutic strategy for AD.

8 Jan 2024

Soft, wearable robot helps a person with Parkinson's to walk without freezing

Freezing is one of the most common and debilitating symptoms of Parkinson's disease, a neurodegenerative disorder that affects more than 9 million people worldwide.

5 Jan 2024

Living alone? Adopting a pet might help slow cognitive decline among older adults

Researchers investigated the association between pet ownership and cognitive decline in the elderly.

3 Jan 2024

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

A group of authors critically evaluated and interpreted the evidence linking mitochondrial dysfunction and metabolic changes to the pathogenesis of Alzheimer's disease (AD).

5 Dec 2023

Saliva analysis breakthrough: Detecting cognitive decline stages in Parkinson’s patients

Researchers used integrative metaproteogenomic analysis to show that changes in salivary microbiota and biomolecules can indicate cognitive impairment stages in Parkinson’s disease patients, offering a potential diagnostic tool.

23 Nov 2023

Shrinkage in the brain's hippocampus area associated with cognitive decline

With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's disease or another neurodegenerative disorder.

15 Nov 2023

Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

Advances in understanding and detecting Alzheimer's disease

Researchers are making strides toward understanding and detecting Alzheimer's disease in its earliest stages, when interventions may be most effective at slowing the progress of the disease.

13 Nov 2023

Tai Chi shows long-term benefits for people with Parkinson's

Tai Chi, the Chinese martial art that involves sequences of very slow controlled movements, may curb the symptoms and complications of Parkinson's disease for several years, reveals research, published online in the Journal of Neurology Neurosurgery & Psychiatry.

25 Oct 2023

Immune system proteins play role in early stages of Huntington's disease

Huntington's Disease is the most common neurodegenerative disorder controlled by a single gene and is characterized by motor and cognitive deficits and psychiatric symptoms.

12 Oct 2023

UArizona to train next generation of Alzheimer's researchers with prestigious NIH grant

A prestigious National Institute on Aging training grant to develop a future workforce of research scientists in the field of Alzheimer's disease and related dementias was awarded to researchers at the Center for Innovation in Brain Science at the University of Arizona Health Sciences.

11 Oct 2023

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.

29 Sep 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.