Neurodegenerative Disease News and Research

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Understanding the gut-brain connection in metabolic and neurological disorders

The community of microorganisms living in the human gut, known as the gut microbiome, is increasingly recognized as playing a pivotal role in metabolic conditions such as obesity and neurological diseases including Parkinson's disease.

9 Nov 2022

Beer hop compounds could serve as the basis for nutraceuticals to combat Alzheimer’s disease

Beer is one of the oldest and most popular beverages in the world, with some people loving and others hating the distinct, bitter taste of the hops used to flavor its many varieties.

7 Nov 2022

Scientists illuminate the molecular events underlying childhood movement disorder

Scientists at the UNC School of Medicine and UNC Eshelman School of Pharmacy, in collaboration with a team from Queen Mary University of London, have illuminated the molecular events underlying an inherited movement and neurodegenerative disorder known as ARSACS – Autosomal recessive spastic ataxia of Charlevoix-Saguenay, named for two Quebec valleys where the first cases were found.

3 Nov 2022

Researchers corroborate the importance of exercise for cognitive function

Accumulating evidence finds that exercise can improve brain function and delay or prevent the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

2 Nov 2022

Appel Alzheimer's Disease Research Institute Symposium reveals new developments in dementia research

The 10th annual Appel Alzheimer's Disease Research Institute Symposium brought fascinating reports of progress in understanding Alzheimer's and related neurodegenerative diseases.

28 Oct 2022

Study identifies an animal model that shares many similarities with progressive MS

A new study from UCLA researchers identified an animal model that could be used to study treatments for improving disabilities in multiple sclerosis patients.

25 Oct 2022

Discovery could affect the search for new Alzheimer's drugs

Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks.

25 Oct 2022

Epigenetic changes related to Parkinson's disease are different in men and women, study says

The epigenetic changes linked to Parkinson's disease – a nervous system disorder that afflicts nearly 1 million Americans – are different in men and women, according to a new Rutgers study published in NPJ Parkinson's Disease.

18 Oct 2022

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

17 Oct 2022

Enterin and Parkinson's Virtual Biotech collaborate to study the effects of ENT-01 on PD-associated dementia

Enterin Inc., a privately held, Philadelphia-based, clinical-stage biopharmaceutical company developing novel treatments for neurodegenerative and metabolic diseases announces a collaboration with the Parkinson's Virtual Biotech, the drug development and discovery arm of Parkinson's UK.

13 Oct 2022

New biosensing technology for detecting Alzheimer’s disease in the blood

Researchers from Hokkaido University and Toppan have developed a method to detect build-up of amyloid β in the brain, a characteristic of Alzheimer's disease, from biomarkers in blood samples.

7 Oct 2022

The neuroprotective potential of Cannabis sativa L. against Alzheimer's disease

A recent study assesses the neuroprotective potential of the active constituents of cannabis in treating dementia and Alzheimer's disease.

6 Oct 2022

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

Spinocerebellar ataxias are a group of neurodegenerative diseases characterized by the degeneration of Purkinje cells, a major class of neurons in the cerebellum.

3 Oct 2022

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Researchers explored the in vivo efficacy of SARS-CoV-2-encoded proteins against neuromuscular degeneration associated with ribosome stalling.

3 Oct 2022

Does leptin play a role in Parkinson’s disease?

Scientists review in vitro and in vivo evidence associated with Parkinson's disease and leptin.

26 Sep 2022

In-home device can monitor Parkinson's patient's movement and gait speed

Parkinson's disease is the fastest-growing neurodegenerative disease, now affecting more than 10 million people worldwide, yet clinicians still face huge challenges in tracking its severity and progression.

21 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Study reveals pathological mechanisms of synaptic dysfunction in patients with Huntington's disease

Huntington's disease (HD) is a hereditary brain disease caused by a mutation in the huntingtin gene. HD is a neurodegenerative disease without a cure that, after the onset of the disease at around 40 years of age, causes changes in personality and symptoms of dementia along with uncontrollable convulsive movements, ultimately leading to death.

19 Sep 2022

Age-related changes in microbiome composition affects brain macrophages

Scientists review the impact of age-related gut microbiome composition on age-associated diseases caused by dysfunctional macrophages within the brain.

13 Sep 2022

Exercise hormone reduces protein levels linked to Parkinson's disease

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice.

12 Sep 2022