Neurodegenerative Diseases News and Research

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Researchers win Jacob Heskel Gabbay Award in Biotechnology and Medicine

Karl Deisseroth of Stanford University, Gero Miesenb-ck of the University of Oxford and Edward S. Boyden of the Massachusetts Institute of Technology have been awarded Brandeis University's 16th Annual Jacob Heskel Gabbay Award in Biotechnology and Medicine.

22 Apr 2013

Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

Ceregene, Inc. today announced the top-line data from its double-blind, randomized, controlled Phase 2b clinical study of CERE-120 (AAV-neurturin), a gene therapy product designed to deliver the neurotrophic factor neurturin, for Parkinson's disease.

20 Apr 2013

Unique modification to microtubules makes nerve cells' cytoskeleton singularly robust

How do nerve cells -- which can each be up to three feet long in humans -- keep from rupturing or falling apart?

16 Apr 2013

NCRI, Prize4Life recognized with Bio-IT World's Best Practices Award for creating PRO-ACT platform

The Massachusetts General Hospital Neurological Clinical Research Institute and Prize4Life, a nonprofit organization whose mission is to accelerate the discovery of treatments and a cure for amyotrophic lateral sclerosis, received a Best Practices Award at the 2013 Bio-IT World Conference & Expo.

15 Apr 2013

Cocoa polyphenols triggers neuroprotection by activating BDNF survival pathway

Epidemiological studies have indicated that dietary habits and antioxidants from diet can influence the incidence of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases.

15 Apr 2013

Many HDLS patients still incorrectly diagnosed

The very serious hereditary disease HDLS was discovered in 1984 in Sweden. Many HDLS patients are still incorrectly diagnosed with Alzheimer's disease, MS or Parkinson's disease, but researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now developed a more certain diagnosis method - and are seeking to find a treatment for the "unknown" neurological disorder.

11 Apr 2013

Research: ACOT7 enzyme keeps neurons' fat levels under control

We're all fatheads. That is, our brain cells are packed with fat molecules, more of them than almost any other cell type. Still, if the brain cells' fat content gets too high, they'll be in trouble. In a recent study in mice, researchers at Johns Hopkins pinpointed an enzyme that keeps neurons' fat levels under control, and may be implicated in human neurological diseases.

9 Apr 2013

Researchers discover that fruit fly mutation holds clues for treating motor neuron diseases

A team of researchers, led by Marc Freeman, PhD, an early career scientist with the Howard Hughes Medical Institute and associate professor of neurobiology at the University of Massachusetts Medical School have discovered a gene in the fruit fly Drosophila melanogaster that, when mutant, blocks the self-destruction of damaged axons, which could hold clues to treating motor neuron diseases, such as amyotrophic lateral sclerosis.

9 Apr 2013

Transposons increase in abundance and activity in brains as they age

As the body ages, the physical effects are notable; wrinkles in the skin appear, physical exertion becomes harder. But there are also less visible processes going on. Inside aging brains there is another phenomenon at work, which may contribute to age-related brain defects.

9 Apr 2013

TSRI scientists identify new drugs for human prion disease

Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems.

4 Apr 2013

RUB biologists report that vitamin P ensures survival of motor neurons in culture

Biologists from the Ruhr-Universit-t Bochum have explored how to protect neurons that control movements from dying off.

3 Apr 2013

Research facilitates development of treatments, cures to Alzheimer's disease

A team of researchers at The New York Stem Cell Foundation Research Institute led by Scott Noggle, PhD, Director of the NYSCF Laboratory and the NYSCF - Charles Evans Senior Research Fellow for Alzheimer's Disease, and Michael W. Nestor, PhD, a NYSCF Postdoctoral Research Fellow, has developed a technique to produce three-dimensional cultures of induced pluripotent stem cells called embryoid bodies, amenable to live cell imaging and to electrical activity measurement.

3 Apr 2013

New laboratory study shows certain protein particles multiply, spread from one cell to another

In diseases like Alzheimer's and Parkinson's endogenous proteins accumulate in the brain, eventually leading to the death of nerve cells. These deposits, which consist of abnormally formed proteins, are supposed to migrate between interconnected areas of the brain, thereby contributing to the development of the illness.

28 Mar 2013

Salk scientists discover how brain keeps track of similar but distinct memories

Ever find yourself racking your brain on a Monday morning to remember where you put your car keys? When you do find those keys, you can thank the hippocampus, a brain region responsible for storing and retrieving memories of different environments-such as that room where your keys were hiding in an unusual spot.

22 Mar 2013

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

A multicenter team of researchers, including scientists at Columbia University Medical Center (CUMC), Brigham and Women's Hospital (BWH), Mount Sinai School of Medicine, and Massachusetts Institute of Technology, has developed biodegradable nanoparticles that are capable of delivering inflammation-resolving drugs to sites of tissue injury.

20 Mar 2013

Rensselaer professor awarded NIH grant to explore cellular function with links to diverse diseases

The interior of every cell within our bodies is crisscrossed with a network of molecular highways upon which nutrients, replacement parts, and other vital materials travel to their appropriate location.

20 Mar 2013

New research project on systems biology of synapse proteins and ageing launched

The AgedBrainSYSBIO project on systems biology of synapse proteins & ageing was officially launched March18th in Paris, France.

20 Mar 2013

Darapladib can significantly reduce leaks in the blood brain barrier

A research team led by Robert Nagele, PhD, of the New Jersey Institute for Successful Aging (NJISA) at the University of Medicine and Dentistry of New Jersey (UMDNJ)-School of Osteopathic Medicine, has demonstrated that the anti-atherosclerosis drug darapladib can significantly reduce leaks in the blood brain barrier.

12 Mar 2013

Acid reflux can kill certain cancer cells

A University of Central Florida chemist has come up with a unique way to kill certain cancer cells - give them acid reflux.

7 Mar 2013

USF, Saneron receive patent for transplantation method using umbilical cord blood cells

Researchers at Saneron CCEL Therapeutics and the University of South Florida have received a patent relating to a method for obtaining and using umbilical cord blood cells from a donor or patient to provide neural cells for transplantation aimed at repairing a variety of neurodegenerative diseases of the brain and spinal cord, such as Parkinson's disease, Huntington's disease, multiple sclerosis, Alzheimer's disease as well as brain and spinal cord injury.

7 Mar 2013

Neurodegenerative Diseases News and Research

Researchers win Jacob Heskel Gabbay Award in Biotechnology and Medicine

Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

Unique modification to microtubules makes nerve cells' cytoskeleton singularly robust

NCRI, Prize4Life recognized with Bio-IT World's Best Practices Award for creating PRO-ACT platform

Cocoa polyphenols triggers neuroprotection by activating BDNF survival pathway

Many HDLS patients still incorrectly diagnosed

Research: ACOT7 enzyme keeps neurons' fat levels under control

Researchers discover that fruit fly mutation holds clues for treating motor neuron diseases

Transposons increase in abundance and activity in brains as they age

TSRI scientists identify new drugs for human prion disease

RUB biologists report that vitamin P ensures survival of motor neurons in culture

Research facilitates development of treatments, cures to Alzheimer's disease

New laboratory study shows certain protein particles multiply, spread from one cell to another

Salk scientists discover how brain keeps track of similar but distinct memories

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

Rensselaer professor awarded NIH grant to explore cellular function with links to diverse diseases

New research project on systems biology of synapse proteins and ageing launched

Darapladib can significantly reduce leaks in the blood brain barrier

Acid reflux can kill certain cancer cells

USF, Saneron receive patent for transplantation method using umbilical cord blood cells

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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