Neurodegenerative Diseases News and Research

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Penn researcher searches for common factor linked to smell loss

Studies have shown that loss of the sense of smell can be among the first warning signs of diseases such as Alzheimer's and Parkinson's.

10 May 2017

Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

With drug resistance being on the rise worldwide, bacterial infections pose one of the greatest global threats to human health. By deciphering the host-pathogen interaction on a molecular level, researchers hope to pave the way for new therapies.

10 May 2017

Scientists show ability to grow specific neurons for treatment of optic neurodegenerative diseases

Scientists have demonstrated the capacity to grow specialized neurons that relay visual data to the brain, creating a source of cells for future treatments of glaucoma and other optic neurodegenerative diseases.

9 May 2017

Dendritic cells develop from specialized progenitors, research shows

Dendritic cells are gatekeepers of Immunity and are crucial for the detection and initiation of Immunity against pathogens and foreign substances. Up to now dendritic cell subtypes were thought to develop from one common progenitor.

5 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

ARVO 2017 to showcase latest advances in treatments for eye disease and blindness

The Annual Meeting of the Association for Research in Vision and Ophthalmology is the largest gathering of eye and vision researchers in the world, with over 11,000 attendees from more than 75 countries.

2 May 2017

SyMRI approach provides myelin maps in scan times of only 5 minutes

It has been a long-standing dream in MRI to move from visualizing tissue contrast differences to directly imaging patient tissue properties. Recent developments within quantitative MRI have provided substantial steps forward in measuring the basic physical properties such as T1 and T2 relaxation times or proton density.

2 May 2017

Structural integrity of the hippocampus could mediate link between fitness and memory

Studies have suggested a link between fitness and memory, but researchers have struggled to find the mechanism that links them. A new study by University of Illinois researchers found that the key may lie in the microstructure of the hippocampus, a region in the middle of the brain involved in memory processes.

2 May 2017

Simple eye test can diagnose early signs of glaucoma

A SIMPLE eye test could help solve the biggest global cause of irreversible blindness, glaucoma. In clinical trials, the pioneering diagnostic -- developed by researchers at University College London and the Western Eye Hospital -- allowed doctors to see individual nerve cell death in the back of the eye.

27 Apr 2017

Study evaluates effectiveness of deep brain stimulation for treatment-resistant schizophrenia patients

Winner of the Best International Abstract Award, Laura Salgado Lopez, MD, presented her research, A Pilot Study of Deep Brain Stimulation in Treatment-resistant Schizophrenia, during the 2017 American Association of Neurological Surgeons Annual Scientific Meeting.

25 Apr 2017

Low levels of NPTX2 protein in the brain may lead to learning and memory loss in Alzheimer's disease

Working with human brain tissue samples and genetically engineered mice, Johns Hopkins Medicine researchers together with colleagues at the National Institutes of Health, the University of California San Diego Shiley-Marcos Alzheimer's Disease Research Center, Columbia University, and the Institute for Basic Research in Staten Island say that consequences of low levels of the protein NPTX2 in the brains of people with Alzheimer's disease (AD) may change the pattern of neural activity in ways that lead to the learning and memory loss that are hallmarks of the disease.

25 Apr 2017

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Biogen today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorization for SPINRAZA to treat patients with spinal muscular atrophy (SMA).

21 Apr 2017

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

With the help of genetically engineered mice, scientists at the Massachusetts General Hospital are moving closer to establishing the role that increased intestinal permeability, sometimes called a "leaky gut," plays in chronic inflammatory conditions.

20 Apr 2017

Study provides evidence that virtual reality could help prevent falls in elderly people

Every year, falls lead to hospitalization or death for hundreds of thousands of elderly Americans. Standard clinical techniques generally cannot diagnose balance impairments before they lead to falls.

20 Apr 2017

Scientists find new way to measure tau protein levels in the blood

Damaging tangles of the protein tau dot the brains of people with Alzheimer's and many other neurodegenerative diseases, including chronic traumatic encephalopathy, which plagues professional boxers and football players.

20 Apr 2017

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

In a recent paper published in the Journal of Biological Chemistry Yuna Ayala, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, and her research team made advances in understanding how a protein causes damaging plaques to build up in neurodegenerative illnesses like amyotrophic lateral sclerosis (ALS) and a form of dementia called frontotemporal lobar degeneration.

19 Apr 2017

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Culminating a nearly 10 year effort, researchers have determined the atomic resolution structure of a key molecule that translates signals from a cell's local environment into a language that the cell can understand and use.

18 Apr 2017

Cell cultures in petri dishes open new doors to brain research

The most complex organ in humans is the brain. Due to its complexity and, of course, for ethical reasons, it is extremely difficult to do scientific experiments on it - ones that could help us to understand neurodegenerative diseases like Parkinson's, for example.

13 Apr 2017

Scientists discover new role for autophagosomes in neurodegenerative diseases

Autophagosomes are at the center of attention, at least since the Nobel Prize for Medicine was awarded for research on autophagy in 2016. The much talked about autophagosomes are small membrane vesicles in charge of waste disposal to promote recycling of its components.

11 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

Neurodegenerative Diseases News and Research

Penn researcher searches for common factor linked to smell loss

Scientists study cell’s reaction to Salmonella by visualizing protein chains at near-molecular level

Scientists show ability to grow specific neurons for treatment of optic neurodegenerative diseases

Dendritic cells develop from specialized progenitors, research shows

Easing cellular traffic jams in Huntington’s disease may save brain cells

ARVO 2017 to showcase latest advances in treatments for eye disease and blindness

SyMRI approach provides myelin maps in scan times of only 5 minutes

Structural integrity of the hippocampus could mediate link between fitness and memory

Simple eye test can diagnose early signs of glaucoma

Study evaluates effectiveness of deep brain stimulation for treatment-resistant schizophrenia patients

Low levels of NPTX2 protein in the brain may lead to learning and memory loss in Alzheimer's disease

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

Study provides evidence that virtual reality could help prevent falls in elderly people

Scientists find new way to measure tau protein levels in the blood

SLU researchers make advances in understanding plaque-causing protein in neurological disorders

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Cell cultures in petri dishes open new doors to brain research

Scientists discover new role for autophagosomes in neurodegenerative diseases

New study finds link between neural tube defects in infants and neurodegenerative diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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