Neurogenesis News and Research

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Neurogenesis (birth of neurons) is the process by which neurons are generated. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain.

Colonization of subventricular neurogenic niche by leukemia cells prevents the formation of new neurons

The subventricular neurogenic niche is a region of the brain where tumor cells can hide from chemotherapy treatment to reappear later, causing relapses in patients with childhood acute lymphoblastic leukemia (ALL), and preventing the formation of new neurons, as demonstrated by research led by Universidad Complutense de Madrid (UCM).

30 Mar 2022

World Sleep Day: Diagnosing chronic respiratory diseases from within the bedroom

For World Sleep Day 2022, News-Medical speaks to Max Sieghold, Co-Founder and CFO of Sleepiz, about their technology and its ability to diagnose sleep apnea/

18 Mar 2022

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Every time you chew, talk, yawn, or sense the zap of a toothache, cranial nerve cells are shuttling electrochemical signals to your brain.

23 Feb 2022

MCL1 regulates neuronal autophagy, cell survival in Alzheimer's disease

Announcing a new review article publication for Acta Materia Medica journal. In this review article, the authors discuss the emerging neuroprotective function of MCL1 and how dysregulation of MCL1 signaling is involved in the pathogenesis of AD.

31 Jan 2022

Researchers discover mechanism behind SARS-CoV-2 entry into the brain

In a new study, researchers conducted an analysis of databases that have information on the transcriptomic and proteomic expression of ACE2, TMPRSS2, NRP1, and furin in several human brain areas.

24 Jan 2022

Study provides valuable insight into the developmental origins of schizophrenia

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders.

16 Jan 2022

Even mild SARS-CoV-2 respiratory-only infection can cause long-term neurologic damage

A new bioRxiv* preprint study led by Michelle Monje of Stanford University in California finds that a mild COVID-19 infection can produce long-term neurological damage. Persistent cognitive complications are one of many symptoms of long COVID, and the latest results suggest the severity of COVID-19 induced brain fog is similar to cancer’s “chemobrain.”

16 Jan 2022

A closer look at the relationship between COVID-19 and Alzheimer’s disease

Researchers discuss the findings of previous studies on the role of SARS-CoV-2 infection in the progression of Alzheimer's Disease.

4 Jan 2022

Researchers uncover the journey of microglia in developing zebrafish

Microglia, the immune cells of the brain, form the first line of defense against neurodegenerative diseases and traumatic brain injuries.

8 Dec 2021

Experts review progress in using photobiomodulation therapy to treat diverse brain disorders

Photobiomodulation (PBM) offers exciting opportunities for improving the life of patients with a diverse range of brain disorders.

14 Oct 2021

High fat diet exacerbates Alzheimer's disease in mouse model

Research has shown that individuals who have diabetes are more prone to develop dementia. Although people are widely aware of diabetes, owing to its common occurrence, they are less aware of prediabetes. Similar to diabetes, prediabetes is also associated with impaired glucose tolerance. However, unlike diabetes, patients with prediabetes show a slight increase in insulin and fasting blood glucose rather than hyperglycemia.

7 Oct 2021

Study sheds new light on the mechanisms required for development of adult-born neurons

A unique interaction between an excitatory neural receptor and a chloride transporter are critical for development of adult-born neurons in the dentate gyrus, according to a Northwestern Medicine study published in Cell Reports.

4 Oct 2021

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Aging-US published "PirB functions as an intrinsic suppressor in hippocampal neural stem cells" which reported that neural stem cells play pivotal roles during prenatal development and throughout life.

20 Aug 2021

Systemic biomarkers show beneficial effects of aerobic exercise on brain function in older adults

Increasing evidence shows that physical activity and exercise training may delay or prevent the onset of Alzheimer's disease (AD). In aging humans, aerobic exercise training increases gray and white matter volume, enhances blood flow, and improves memory function.

10 Jun 2021

Research offers new hope for people affected by the microdeletion of chromosome 22

One person in 2000 suffers from a microdeletion of chromosome 22 that can lead to the development of psychotic disorders, such as schizophrenia, in adolescence.

1 Jun 2021

Lactate has antidepressant effect in mice, shows study

Depression is the leading cause of disability worldwide. Neuroscientists from Synapsy - the Swiss National Centre of Competence in Research into Mental Illness - based at Lausanne University Hospital (CHUV) and Lausanne University (UNIL) have recently demonstrated that lactate, a molecule produced by the body during exercise, has an antidepressant effect in mice.

28 May 2021

Newly identified small molecule can be used to rejuvenate the brain, counteract memory loss

Alzheimer's disease is the main cause of dementia and current therapeutic strategies cannot prevent, slow down or cure the pathology.

25 May 2021

New pan-European survey explores the effect of COVID-19 restrictions on physical, mental health

A new pan-European survey funded by the Institute for Scientific Information on Coffee exploring the impact of COVID-19 Lockdowns and associated restrictions (in those countries where there has been no Lockdown), has found that nearly two thirds of adults (61%) expressed concern about their worsening mood; two times higher than those concerned about physical inactivity (24%).

20 May 2021

Scientists identify many genes that are important in fruit flies' neuron development

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

27 Apr 2021

Study: Age-related changes in brain stem cells are more pronounced in male animals

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis. This process is important for learning and cognitive function which declines as the brain ages.

9 Apr 2021