Neuropharmacology News and Research

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Synergy between two neurotrophic factors exerts beneficial effect in early phase of Parkinson’s disease

Parkinson's disease is currently the second most widespread neurogenerative pathology. Current therapies are mainly of a replacement type and pose problems in the long term, so the challenge is to establish an early diagnosis and develop neuroprotective and neurorestorative therapies that will allow the symptoms of the disease to be slowed down or even reversed.

12 Jan 2018

Magic mushrooms substance Psilocybin on trial for treatment of depression

There are ongoing studies that look at the effect of hallucinogenic psychedelic substance Psilocybin or “magic mushrooms” in the treatment of depression.

9 Jan 2018

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.

5 Dec 2017

Measuring biological samples using SNAP

My group is interested in host pathogen interaction and we mainly focus on how bacteria enter cells. In essence, the idea is that if you can prevent bacteria from entering cells, then you will prevent illness.

From Bruker Nano Surfaces 24 Oct 2017

University and pediatric hospital work together to improve lives of children with epilepsy

Since 2010, investigators and clinicians at Aston University and Birmingham Children's Hospital have worked together to try and improve the lives of children with difficult to treat forms of epilepsy.

5 Sep 2017

A blood test that can diagnose PTSD may be on the horizon

Doctors may soon be able to diagnose post-traumatic stress disorder (PTSD) using a simple blood test, after scientists identified genetic changes in soldiers who experienced trauma after serving time in Afghanistan.

4 Sep 2017

PTSD screening using genetic markers could be a reality soon

A new study from researchers in the Netherlands, shows that persons who are affected with PTSD (Post-Traumatic Stress Disorder) can show changes in microRNA (miRNA) molecules that are linked to genetic regulation.

3 Sep 2017

New approach to treating neonatal hypoxic ischemia improves outcomes in preclinical models

Hypothermia alone, the current standard of care, neuroprotects roughly 50 percent of newborns with moderate to severe hypoxic ischemia. Therefore, half of all affected newborns are left with developmental, cognitive and motor delays including cerebral palsy following injury.

1 Sep 2017

UC Irvine pharmacology researchers unearth potential roots of schizophrenia

An abundance of an amino acid called methionine, which is common in meat, cheese and beans, may provide new clues to the fetal brain development that can manifest in schizophrenia, University of California, Irvine pharmacology researchers report in the journal Molecular Psychiatry.

16 Aug 2017

Potential drug offers hope for therapy-resistant breast cancer patients

UT Southwestern Simmons Cancer Center researchers have shown that a first-in-class molecule can prevent breast cancer growth when traditional therapies stop working.

8 Aug 2017

Study opens new range of therapeutic options for patients with atypical Rett syndrome

A translational, multicenter study carried out by research groups of the Bellvitge Biomedical Research Institute, San Juan de Dios Hospital, the University of Barcelona, Clinic Hospital, the University of Vic, Santa Creu i Sant Pau Hospital and the thematic area of Rare Diseases, has unveiled the potential of D-serine -- a dietary supplement -- to improve the neuronal function of a patient with a mutation of the glutamate receptors associated to atypical Rett syndrome with severe encephalopathy.

4 Jul 2017

Biomedical engineers develop new method for delivering drugs to specific neurons

Biomedical engineers have developed a way to deliver drugs to specific types of neurons in the brain, providing an unprecedented ability to study neurological diseases while also promising a more targeted way to treat them.

6 Apr 2017

Gene that helps form trauma-related memories can be manipulated to prevent PTSD, study finds

A specific gene that helps form memories from traumatic events can be manipulated -- and in doing so may actually help prevent post-traumatic stress disorder (PTSD), according to a new study led NYU Langone Medical Center that recently published in Neuropharmacology.

13 Feb 2017

Study looking for toxicity markers in smokers who replace tobacco for e-cigarettes seeks volunteers

The first study to closely follow toxicity markers in smokers who replace tobacco for e-cigarettes is seeking volunteers.

2 Feb 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

Viral infection during pregnancy affects maternal care and can trigger depression in offspring

A viral infection in a pregnant woman not only affects her subsequent ability to provide maternal care but can also trigger depression in her offspring, which can then even extend into the next generation as a result of changes to genetic mechanisms in the brain.

15 Dec 2016

UC Irvine study shows how YHS effectively treats different forms of pain

Root extracts from the flowering herbal plant Corydalis yanhusuo, or YHS, has widely used for centuries as a pain treatment. Yet few studies have investigated how it works on different forms of pain, and little is known about its molecular mechanisms.

14 Sep 2016

SCIEX and QPS Holdings enter collaboration to establish the BioBA solution for bioanalysis of biologics

SCIEX, a global leader in life science analytical technologies, and QPS Holdings, LLC (QPS), a leading global full-service Contract Research Organization (CRO), today announced a collaboration to advance Hybrid LBA –LCMS, a workflow for routine biologics quantification. Under the agreement, QPS Holdings will deploy the SCIEX BioBA Solution, the first end-to-end and most complete solution for bioanalysis of biologics.

6 Apr 2016

Researchers develop new painkiller as strong as morphine but not addictive

Researchers at Tulane University and Southeast Louisiana Veterans Health Care System have developed a painkiller that is as strong as morphine but isn't likely to be addictive and with fewer side effects, according to a new study in the journal Neuropharmacology.

29 Jan 2016

Small differences in specific genetic variant could alter nicotine consumption

Nicotine is an addictive substance and genetic factors are known to play a role in smoking behaviors. Recently, a team of researchers at Penn State and the University of Colorado determined how small differences in a particular region of the mouse genome can alter nicotine consumption.

11 Jan 2016