Neutrophils News and Research

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Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

A new study published in the journal Life Sciences has focused on examining the effects of ORF8 and ORF10 genes and SARS-CoV-2 Membrane (M) protein on apoptosis.

17 May 2022

Inflammation plays a key role in resolving pain

In a recent study published in the journal Science Translational Medicine, researchers explored the mechanisms underlying the transition from acute to chronic low back pain (LBP) by transcriptome-wide analysis of peripheral immune cells from acute LBP patients.

17 May 2022

Research reveals how a leaky gut leads to inflammation in the lungs

Why are older adults more likely to get seriously ill or even die from pneumonia? It turns out the cause may have as much to do with the gut as it does with the lungs.

11 May 2022

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

In this study, the authors have specifically studied the interactions of epithelial cells, a subset of cytokines and macrophages.

10 May 2022

Pathogenicity and transmissibility of SARS-CoV-2-related pangolin coronavirus

Researchers observed that pangolin coronaviruses related to SARS-CoV-2 share similar pathogenicity and transmissibility in hamsters.

6 May 2022

Scientists explore immunopathology of COVID-19

Researchers explored the interactions between severe acute respiratory syndrome coronavirus 2 and the host in the development of COVID-19.

6 May 2022

Multi-omics identify COVID-19 severity predictors and prothrombotic signatures in patients with end-stage kidney disease

Researchers demonstrated that plasma levels of leucine-rich repeat-containing 15 are a strong indicator of the severity of COVID-19 in patients with end-stage kidney disease.

3 May 2022

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body.

29 Apr 2022

How do mosquito bites affect immunity?

A new study looks at the immunomodulatory effects of mosquito bites, using Aedes aegypti as the model species and humans as the host.

28 Apr 2022

Penn scientists discover how one inflammatory disorder increases susceptibility to another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response.

27 Apr 2022

Study explores SARS-CoV-2 antibody responses in mild COVID-19 cases

In a new study, researchers evaluated antibody responses in mild cases of coronavirus disease 2019.

26 Apr 2022

Durability and neutralization capacity of SARS-CoV-2 specific antibodies in the breastmilk of convalescent COVID-19 mothers

The researchers assessed immunological and pathophysiological aspects of antenatal COVID-19.

26 Apr 2022

Effects of COVID-19 treatment best with combination therapy

There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.

15 Apr 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

Researchers discover new mechanisms for bone loss in gum disease

Tokyo University of Agriculture and Technology researchers reported on a new discovery regarding the mechanisms for bone loss in gum disease (periodontitis). They found that double stranded RNA molecules can activate the immune system response that leads to deterioration of bone.

8 Apr 2022

Depressive disorders are associated with general increase in the deformability of immune cells

A recent study by the TU Dresden and the University of Zurich in cooperation with the Max Planck Institute for the Science of Light establishes for the first time a link between depressive disorders and mechanical characteristics of all major blood cell types.

8 Apr 2022