Neutrophils News and Research

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UAB study reveals detrimental role of neutrophils in multiple sclerosis

Multiple sclerosis is an autoimmune disease that damages the insulating sheaths of nerve cells of the central nervous system. People with the disease can lose vision, suffer weak limbs, show degenerative symptoms and exhibit impaired cognition.

26 May 2019

Early clinical trial of new treatment for severe dry eye disease shows promising results

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a paper in Translational Vision Science and Technology.

7 May 2019

KAIST research team finds cause of sepsis-induced lung injury

A KAIST research team succeeded in visualizing pulmonary microcirculation and circulating cells in vivo with a custom-built 3D intravital lung microscopic imaging system.

7 May 2019

World Asthma Day: How climate change is increasing cases of asthma

A new report suggests that climate change is increasing and exacerbating cases of asthma, and clinicians need to become more 'knowledgeable' about the link.

7 May 2019

Study shows how neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death

Many chronic disorders arise from misdirected immune responses. A Ludwig-Maximilians-Universitaet in Munich team led by Oliver Söhnlein now shows that neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death and that a tailored peptide inhibits the process.

2 May 2019

Key research takeaways from ECCMID 2019

This article aims to provide a brief overview of the key themes of the 29th ECCMID conference and update readers on current research projects.

From ESCMID 19 Apr 2019

Increased neutrophil lifespan may contribute to intestinal inflammation in HIV-infected individuals

The increased survival of white blood cells called neutrophils is associated with alterations in the intestinal microbiome of HIV-infected individuals, according to a study published April 11 in the open-access journal PLOS Pathogens by Nichole Klatt of the University of Miami, and colleagues.

11 Apr 2019

Researchers identify alternative treatment for bacterial meningitis

With the increasing threat of antibiotic resistance, there is a growing need for new treatment strategies against life threatening bacterial infections.

10 Apr 2019

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic.

10 Apr 2019

Study of pregnant women with lupus identifies early indicators of pregnancy complications

A study of pregnant women with systemic lupus erythematosus has identified early changes in the RNA molecules present in the blood that could be used to determine the likelihood of them developing preeclampsia.

8 Apr 2019

FDA extends indication of metastatic breast cancer treatment to include male patients

The U.S. Food and Drug Administration today is extending the indication of Ibrance (palbociclib) capsules in combination with specific endocrine therapies for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in male patients.

5 Apr 2019

Childhood asthma may be eased by omega-3 intake

A small study has suggested that symptoms of childhood asthma may be eased by omega-3 intake, while omega-6 may aggravate the condition.

2 Apr 2019

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Critical Path Institute announced today that a formal consultation between its Predictive Safety Testing Consortium and Japan's Pharmaceuticals and Medical Devices Agency has resulted in an agreement on a first-of-its-kind approach to compare the levels of eight novel urinary kidney safety biomarkers in healthy Japanese volunteers to data collected on these same biomarkers in healthy Western volunteers in a bridging study.

27 Mar 2019

Mayo Clinic study identifies potential new drug therapy for liver diseases

Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers.

22 Mar 2019

Mother's diet during pregnancy can impact lung-specific genes of her offspring

Children born to women pregnant during the Dutch famine were more likely to have a constellation of health problems including cardiovascular disease and asthma, but the exact mechanisms that cause this epigenetic inheritance have not been fully explored.

20 Mar 2019

Study reveals how the microbiota controls activity of immune cells

A host protein called Serum Amyloid A (Saa) is a major factor mediating the effects of the microbiota on the function of immune cells called neutrophils, according to a study published March 7 in the open-access journal PLOS Pathogens by John Rawls of Duke University School of Medicine, and colleagues.

8 Mar 2019

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these two factors regulate the immune response is not well-understood.

1 Mar 2019

Best proven drug to treat schizophrenia could be safely given to African descent people

A study led by researchers at Cardiff University means that more people of African descent who have treatment-resistant schizophrenia could be safely given the drug best proven to manage their symptoms.

27 Feb 2019

New protocol can help identify febrile infants at low risk for serious bacterial infections

A national research team led by UC Davis Health clinicians and researchers from the University of Michigan, Nationwide Children's Hospital and Columbia University, has derived and validated a new protocol for emergency departments that can determine which infant patients with fevers, age 60 days or younger, are at low risk of significant bacterial infections.

18 Feb 2019

New protocol could help physicians to rule out bacterial infections in infants

A new protocol could help emergency room physicians to rule out life-threatening bacterial infections among infants up to 2 months of age who have fevers, potentially eliminating the need for spinal taps, unnecessary antibiotic treatments or expensive hospital stays.

18 Feb 2019

Neutrophils News and Research

UAB study reveals detrimental role of neutrophils in multiple sclerosis

Early clinical trial of new treatment for severe dry eye disease shows promising results

KAIST research team finds cause of sepsis-induced lung injury

World Asthma Day: How climate change is increasing cases of asthma

Study shows how neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death

Key research takeaways from ECCMID 2019

Increased neutrophil lifespan may contribute to intestinal inflammation in HIV-infected individuals

Researchers identify alternative treatment for bacterial meningitis

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

Study of pregnant women with lupus identifies early indicators of pregnancy complications

FDA extends indication of metastatic breast cancer treatment to include male patients

Childhood asthma may be eased by omega-3 intake

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Mayo Clinic study identifies potential new drug therapy for liver diseases

Mother's diet during pregnancy can impact lung-specific genes of her offspring

Study reveals how the microbiota controls activity of immune cells

Aging and high-fat diet disrupt gut microbiome to cause inflammation in heart failure

Best proven drug to treat schizophrenia could be safely given to African descent people

New protocol can help identify febrile infants at low risk for serious bacterial infections

New protocol could help physicians to rule out bacterial infections in infants

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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