Neutrophils News and Research

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Activation of the STING pathway could help make glioblastoma multiforme more susceptible to immunotherapy

Immunotherapy has revolutionized treatment for many forms of cancer, but glioblastoma multiforme (GBM), the most common and deadly form of brain cancer, has remained untouched.

11 Jul 2022

The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Researchers characterized the clinical isolates of SARS-CoV-2 Omicron BA.4 and BA.5.

8 Jul 2022

Targeting C5a/C5aR1 signaling ameliorates COVID-19 immunopathology

A new study investigated the role of complement component 5a (C5a) and its receptor (C5a receptor type 1, C5aR1) in the pathophysiology of COVID-19.

6 Jul 2022

Bisphosphonates appear to improve COVID-19 exposure outcomes

A new retrospective study examines the effect of bisphosphonates on COVID-19 outcomes.

27 Jun 2022

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers evaluated the efficacy of PHELA, a traditional African drug, against SARS-CoV-2 in vitro.

21 Jun 2022

Math model predicts several useful new drug combinations that may help treat heart attacks

Researchers used mice to develop a mathematical model of a myocardial infarction, popularly known as a heart attack.

17 Jun 2022

Fc-effector functions for selecting COVID-19 convalescent plasma

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that coronavirus disease 2019 (COVID-19) convalescent plasmas (CCPs) with low neutralizing and high fragment crystallizable (Fc)-effector activity result in effective prophylaxis.

15 Jun 2022

Study reveals the dynamics of disease recovery after severe COVID-19

Recovery from severe COVID-19 is characterized by a reduction of certain white blood cells and changes in the molecular regulation of the immune system.

15 Jun 2022

Emory researchers identify key immune cell type that drives the transition from early to late COVID-19

Determining how SARS-CoV-2, the virus causing COVID-19, moves from an early stage of infection, when patients are largely asymptomatic, into a later stage when people may experience life-threatening inflammation in the lungs, is a critical step in understanding how to target and treat the disease more efficiently.

14 Jun 2022

MIT researchers design new sensor to distinguish between viral and bacterial pneumonia

Many different types of bacteria and viruses can cause pneumonia, but there is no easy way to determine which microbe is causing a particular patient's illness.

13 Jun 2022

Gastrointestinal complications caused by SARS-CoV-2

scientists discuss the gastrointestinal complications associated with COVID-19.

7 Jun 2022

Brain motor and fear circuits orchestrate the immune response to acute stress

A new study explores how acute stressors affected mice in terms of their immune responses in specific regions of the brain.

2 Jun 2022

Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19

Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests.

1 Jun 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Investigators demonstrated S100A9 as an inflammatory biomarker among hospitalized SARS-CoV-2 patients.

20 May 2022

Researchers discover possible connection between harmful amyloid production and COVID-19 symptoms

In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers at Linköping University, Sweden, have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid.

19 May 2022

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists discuss how SARS-CoV-2 utilizes myeloid cells to allow for the subsequent viral colonization in the lungs.

19 May 2022

STOP-COVID19 trial: Brensocatib did not improve clinical status of patients with severe SARS-CoV-2 infection

Brensocatib did not improve the clinical status of patients hospitalized with severe SARS-CoV-2 infection in the double-blind randomized, placebo-controlled STOP-COVID19 multicenter clinical trial, according to research published at the ATS 2022 international conference.

18 May 2022

Study explores neurologic complications in pediatric COVID-19 cases

Researchers evaluated neurologic complications in pediatric cases of COVID-19.

18 May 2022

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

A new study published in the journal Viruses aimed to report the effects of plasma infusion and then breastmilk ingestion as a therapy for persistent SARS-CoV-2 infection in a patient with a common variable immunodeficiency (CVID) phenotype.

18 May 2022

Neutrophils News and Research

Activation of the STING pathway could help make glioblastoma multiforme more susceptible to immunotherapy

The replicative ability and pathogenicity of Omicron BA.4 and BA.5 isolates in hamsters

Targeting C5a/C5aR1 signaling ameliorates COVID-19 immunopathology

Bisphosphonates appear to improve COVID-19 exposure outcomes

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Math model predicts several useful new drug combinations that may help treat heart attacks

Fc-effector functions for selecting COVID-19 convalescent plasma

Study reveals the dynamics of disease recovery after severe COVID-19

Emory researchers identify key immune cell type that drives the transition from early to late COVID-19

MIT researchers design new sensor to distinguish between viral and bacterial pneumonia

Gastrointestinal complications caused by SARS-CoV-2

Brain motor and fear circuits orchestrate the immune response to acute stress

Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Researchers discover possible connection between harmful amyloid production and COVID-19 symptoms

Researchers explore SARS-CoV-2 infection in lung myeloid cells

STOP-COVID19 trial: Brensocatib did not improve clinical status of patients with severe SARS-CoV-2 infection

Study explores neurologic complications in pediatric COVID-19 cases

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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