Nitric Oxide News and Research

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Exposure to low doses of mercury changes the way the arteries work

An international team of researchers has shown that mercury is another important factor in cardiovascular disease as it changes the way arteries work. One of the possible sources of exposure of humans to mercury is by eating contaminated fish.

23 Oct 2008

Aires Pharmaceuticals signs license agreement with NIH

Aires Pharmaceuticals Inc. today announced the signing of an exclusive license agreement with the U.S. National Institutes of Health for the patented use of a nitric oxide prodrug to treat cardiopulmonary conditions.

22 Oct 2008

Discovery may help complications of diabetes - delayed gastric emptying or gastroparesis

Mayo Clinic researchers have found what may provide a solution to one of the more troubling complications of diabetes -- delayed gastric emptying or gastroparesis.

25 Sep 2008

NicOx updates on PF-03187207 and research collaboration with Pfizer

NicOx S.A. has announced the results of a dose-ranging phase 2 study conducted with PF‑03187207 in Japanese patients with glaucoma by its partner Pfizer Inc. PF-03187207 is a nitric oxide-donating prostaglandin analog. The study was designed to compare the safety and efficacy of several doses of PF-03187207 to Xalatan (latanoprost) and enrolled 112 Japanese patients with primary open-angle glaucoma or ocular hypertension.

25 Aug 2008

Blood pressure response to daily stress provides clues for better hypertension treatment

How the body regulates blood pressure in response to daily stress is the focus of a study geared toward helping people whose pressure is out of control.

14 Aug 2008

Allergy to road traffic

Allergic diseases appear more often in children who grow up near busy roads. This is the result of a study of several thousand children, now published in the American Journal of Respiratory and Critical Care Medicine.

14 Jul 2008

Watermelon provides Viagra-like effects

A cold slice of watermelon has long been a Fourth of July holiday staple. But according to recent studies, the juicy fruit may be better suited for Valentine's Day.

30 Jun 2008

Flavanols in cocoa improve artery function, help relieve stress on heart

For people with diabetes, sipping a mug of steaming, flavorful cocoa may seem a guilty pleasure. But new research suggests that indulging a craving for cocoa can actually help blood vessels to function better and might soon be considered part of a healthy diet for the prevention of cardiovascular disease.

26 May 2008

Drug therapy for phenylketonuria reverses heart damage

A pricy drug used to treat a rare but well-known genetic disorder may hold wider promise as a treatment for millions of Americans with potentially lethal enlarged hearts, due mainly to high blood pressure, a study from Johns Hopkins shows.

13 May 2008

Nitrates in vegetables protect against gastric ulcers

Vegetables that are rich in nitrates protect the stomach from damage. This takes place through conversion of nitrates into nitrites by the bacteria in the oral cavity and subsequent transformation into biologically active nitric oxide in the stomach. The Swedish researcher Joel Petersson has described the process, which also means that antibacterial mouthwashes can be harmful for the stomach.

7 May 2008

Sport and asthma, researchers follow European Olympic athletes to Beijing

The pan-European study will allow scientists to specify the prevalence of asthma, exercise induced asthma and other allergic diseases among European athletes qualified for the Beijing Olympics, while identifying the differences in prevalence between a wide range of sports and between the different European regions.

6 May 2008

Hydrogen sulphide may be involved in regulating blood pressure

Hydrogen sulphide is a gas most commonly associated with the smell of stink bombs, sewage and rotten eggs, but a team of researchers from the Peninsula Medical School in the South West of England and King's College London have now identified a role for this gas in regulating blood pressure, according to research published in the leading science journal "Circulation".

29 Apr 2008

How Staphylococcus aureus resists our natural defenses

Researchers at the University of Washington have uncovered how the bacterium Staphylococcus aureus, including the notorious MRSA (methicillin-resistant Staph aureus) "superbug" strains, resists our body's natural defenses against infection.

25 Mar 2008

NicOx signs agreement for commercial manufacture of Naproxcinod drug substance

NicOx S.A. (Euronext Paris: COX) has announced it has signed an agreement with the fine chemical company Archimica, for the commercial manufacturing and supply of naproxcinod drug substance (or active pharmaceutical ingredient, API).

20 Mar 2008

How diabetes drives atherosclerosis

Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research. Experts once believed that atherosclerosis, or hardening of the arteries, developed when too much cholesterol clogged arteries with fatty deposits called plaques.

14 Mar 2008