Non Hodgkin Lymphoma News and Research

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Novel treatment targets against natural killer/T-cell lymphoma identified

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has discovered that a transcription factor, TOX2, was aberrantly increased in patients with Natural killer/T-cell lymphoma (NKTL).

29 May 2023

Combination treatment shows promise for aggressive subtype of non-Hodgkin lymphoma

Nearly 90 percent of patients with an aggressive subtype of non-Hodgkin lymphoma had their cancer go into remission in a small phase 2 clinical trial testing a treatment aimed at making chemotherapy more effective, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

5 May 2023

How to increase your social network as you age

Friends sitting around a table, talking and laughing. A touch on the arm, as one of them leans over to make a confiding comment. A round of hugs before walking out the door.

28 Apr 2023

Exposure to 4 or more CT scans before adulthood doubles the risk for cancers

For children under age 18 years, a single computed tomography (CT) scan is not associated with an increased risk of brain tumors, leukemia or lymphoma, but exposure to 4 or more scans before adulthood more than doubles the risk, according to new research https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221303 in CMAJ.

24 Apr 2023

Radioimmunotherapy cures human non-Hodgkin lymphoma in animal model

A new nuclear medicine therapy can cure human non-Hodgkin lymphoma in an animal model, according to research published in the April issue of The Journal of Nuclear Medicine.

11 Apr 2023

Cancer-causing viruses use a human protein to evade the innate immune response

The viruses Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) have been linked to several cancers.

6 Feb 2023

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, according to a multi-institutional preclinical study led by Weill Cornell Medicine investigators.

19 Jan 2023

Study elucidates the potential role of STRO-001 in B-cell non-Hodgkin lymphoma

A new research paper was published in Oncotarget's Volume 14 on January 12, 2023, entitled, "Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001."

18 Jan 2023

Ongoing Phase I clinical trial demonstrates successful re-treatment with CAR T cell therapy

Researchers from the University of Pennsylvania's Abramson Cancer Center presented preliminary results of an ongoing Phase I clinical trial demonstrating successful re-treatment with CAR T cell therapy for patients whose cancers relapsed after previous CAR T therapy at the 2022 American Society of Hematology Annual Meeting.

12 Dec 2022

One Medicine: how human and veterinary medicine can benefit each other

News-Medical speaks to Professor Roberto La Ragione, Chair of Trustees at Humanimal Trust, about the concept of One Medicine and how human and veterinary medicine can collaborate, share knowledge, and initiate research for the benefit of both humans and animals.

26 Oct 2022

Researchers streamline way to manufacture CAR T-cells in just 24 hours

Researchers at University Hospitals (UH) Seidman Cancer Center and a biotech start-up company have developed a streamlined way to manufacture CAR T-cells for immunotherapy treatment in just 24 hours – an improvement over the team's previous benchmark of eight days and commercial suppliers that typically take three weeks.

25 Oct 2022

Physical exercise improves cardiorespiratory fitness, alleviates adverse effects of cancer treatment

During chemotherapy, physical exercise intervention is safe, improves long-term cardiorespiratory fitness, and alleviates some of the adverse effects of cancer treatment, according to a study published in JACC: CardioOncology.

18 Oct 2022

Embedded bias: How medical records sow discrimination

David Confer, a bicyclist and an audio technician, told his doctor he "used to be Ph.D. level" during a 2019 appointment in Washington, D.C. Confer, then 50, was speaking figuratively: He was experiencing brain fog — a symptom of his liver problems. But did his doctor take him seriously? Now, after his death, Confer's partner, Cate Cohen, doesn't think so.

26 Sep 2022

What are the effects of pesticides on neonates' health?

A new study explores the impact of pesticide exposure in neonates, reviewing current literature while evaluating the research methods used in this area.

20 Sep 2022

New national center strengthens NHS cancer services

Researchers from the London School of Hygiene & Tropical Medicine (LSHTM) will co-lead a new national center of excellence with the Royal College of Surgeons (RCS England) to strengthen NHS cancer services by looking at treatments and patient outcomes right across England and Wales.

13 Sep 2022

International Agency for Research on Cancer classifies firefighting as carcinogenic

The International Agency for Research on Cancer recently classified occupational exposure as a firefighter as carcinogenic, changing the previous classification of possibly carcinogenic.

20 Jul 2022

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to an analysis by investigators from Weill Cornell Medicine and other leading health institutions.

28 Jun 2022

Ibrutinib plus chemoimmunotherapy prolonged progression-free survival in previously untreated mantle cell lymphoma patients

Combination chemoimmunotherapy with the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib demonstrated improved progression-free survival over standard chemoimmunotherapy for previously untreated mantle cell lymphoma (MCL) in patients 65 and over, researchers from The University of Texas MD Anderson Cancer Center reported today at the 2022 American Society of Clinical Oncology Annual Meeting.

3 Jun 2022

NCCN announces the recipients of 2022 awards for oncology champions advancing cancer care

The National Comprehensive Cancer Network today announced the recipients of 2022 awards for both internal and external champions advancing NCCN's mission and helping all people with cancer to live better lives.

23 May 2022

Medicaid expansion associated with increase in survival rates among patients newly diagnosed with cancer

A new large study led by researchers at the American Cancer Society (ACS) shows Medicaid expansion under the Affordable Care Act (ACA) was associated with an increase in two-year overall survival rates among patients newly diagnosed with cancer, especially among non-Hispanic Black people and people living in rural areas.

18 May 2022