Norepinephrine News and Research

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Beta blockers capable of reducing stress signaling may enhance effectiveness of immunotherapy

While the development of therapies designed to block "checkpoints" within the immune system has been one of the most exciting and noteworthy advances in cancer research in recent years, it's also been one of the most puzzling, leaving researchers to ask: Why don't these new therapies work for more patients, and why is their efficacy in controlling cancerous tumors often short-lived? A research team from Roswell Park Cancer Institute has shown that at least one answer -; and an excellent opportunity for unleashing the full potential of these promising immunotherapies -; may lie in the body's "fight or flight" reaction to stressors and in drugs already widely used to control and temporarily disable this stress response.

31 Aug 2017

Adults with autism found to be less surprised by unexpected images

Adults with autism may overestimate the volatility of the world around them, finds a new UCL study published in Nature Neuroscience.

31 Jul 2017

Loss of smell linked to weight loss in mice despite same food intake, study reveals

Experiments conducted at the University of California, Berkeley, suggest that the odor of food has a direct link with how the body processes the calories. The new study conducted on mice published in the first week of July in the journal Cell Metabolism implicates that the ability to detect the smell of food is related to whether the calories are burnt rather than stored.

6 Jul 2017

Sense of smell may play key role in how the body deals with calories

Our sense of smell is key to the enjoyment of food, so it may be no surprise that in experiments at the University of California, Berkeley, obese mice who lost their sense of smell also lost weight.

5 Jul 2017

Researchers uncover novel mechanism of beta-blockers in preventing progression of heart failure

Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines - substances like epinephrine and norepinephrine - which overexcite and stress the heart.

4 Jul 2017

Study shows correlation between urinary stress hormones and coronary heart disease

Stress, especially in women, is increasingly being recognized as a major risk factor for coronary heart disease, a condition in which blood vessels to the heart are blocked by plaque buildup or inflammation.

14 Jun 2017

Single bout of exercise can have significant positive behavioral and cognitive effects

In a new review of the effects of acute exercise published in Brain Plasticity, researchers not only summarize the behavioral and cognitive effects of a single bout of exercise, but also summarize data from a large number of neurophysiological and neurochemical studies in both humans and animals showing the wide range of brain changes that result from a single session of physical exercise.

12 Jun 2017

Study: Angiotensin II can safely improve blood pressure among critically ill patients with hypotension

Sixty years after Cleveland Clinic researchers first isolated the role of angiotensin II in controlling blood pressure, a new international study led by Cleveland Clinic researchers shows that the compound can safely improve blood pressure among critically ill patients who are experiencing life-threatening hypotension, or low blood pressure.

22 May 2017

Researchers discover neurons that help fruit flies to balance sleep and sex

Sleep is important, but if there is something more important or interesting to do -- for example, taking care of a baby, finishing a grant proposal before a deadline, or reading a fascinating book -- we may stay up late.

18 May 2017

University of Guelph researcher discovers effective way to treat shortness of breath in heart failure

Shortness of breath is the No.1 complaint of people suffering from heart failure. Now a University of Guelph researcher has discovered its surprising cause - and an effective treatment - in a groundbreaking new study.

17 May 2017

PTSD and psychoactive drugs linked to increased risk for dementia

Researchers are discovering that post-traumatic stress disorder (PTSD) is a significant risk factor in developing dementia.

9 May 2017

Discovery of signaling pathway offers new functional framework for treating schizophrenia

Neuroscientists at Tufts University School of Medicine have discovered a new signaling pathway that directly connects two major receptors in the brain associated with learning and memory – the N-methyl-D-aspartate receptor (NMDAR) and the alpha 7 nicotinic acetylcholine receptor (a7nAChR) – which has significance for current efforts to develop drugs to treat schizophrenia.

4 May 2017

Experts aim to develop noninvasive technology that accelerates learning

The adage "put your thinking caps on" might evoke visions of an elementary classroom, where a teacher has just admonished cherubic little learners about to embark on a particularly difficult academic adventure.

26 Apr 2017

Personalized approach to pharmacotherapy may provide advances in treatment of panic disorders

Although drug therapy is the accepted first-line treatment for panic disorders, 17% to 64% of patients do not respond adequately and continue to exhibit one of the most common symptoms of PD, the panic attack.

26 Apr 2017

Research findings could lead to new approaches for preventing infections after stroke

Having a stroke damages immune cells as well as affecting the brain, research has found. The findings help explain why patients have a greater risk of catching life-threatening infections, such as pneumonia, after having a stroke.

20 Apr 2017

Scientists use time-lapse video to identify cells that trigger blood stem cell development

Like private investigators on a stake out, St. Jude Children's Research Hospital scientists used patience and video surveillance-like tools to identify cells that trigger blood cell development.

10 Apr 2017

Stress affects more than 70% of Americans, study finds

In recognition of April's National Stress Awareness Month, Youfit Health Clubs conducted a survey to reveal America's stress levels and stress-related habits. The study found that more than 70% of Americans suffer from stress, and of those, more than half deal with stress on a daily or weekly basis.

4 Apr 2017