Nucleic Acid News and Research

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Crumpled grapheme can be more sensitive in detecting DNA cancer markers

Graphene-based biosensors could usher in an era of liquid biopsy, detecting DNA cancer markers circulating in a patient's blood or serum. But current designs need a lot of DNA.

24 Mar 2020

GlobalData: Thermo Fisher to be major player in COVID-19 diagnostic tests following acquisition of Qiagen

Thermo Fisher Scientific is expected to produce millions of coronavirus (COVID-19) diagnostic tests following the acquisition of Qiagen for an approximate transaction value of US$11.5bn per share, says GlobalData, a leading data and analytics company.

From Thermo Fisher Scientific Inc. 20 Mar 2020

High-throughput screening of AAV vector capsid libraries reveals unexpected insights

Researchers have used high-throughput screening of adeno-associated viral (AAV) vector capsid libraries to maximize the likelihood of obtaining AAV variants with desired properties.

18 Mar 2020

How a virus forms a protective shell to evade the immune system

A virus is a small infectious agent that replicates only inside the living cells of an organism. Viruses can infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea.

10 Mar 2020

Researchers find link between interferon, neuroinflammation and synapse loss in Alzheimer's

When immunologist Dr. Wei Cao joined Baylor College of Medicine three-and-a-half years ago, her first project was to investigate how inflammation contributes to Alzheimer's disease.

5 Mar 2020

Supersensitive nanomaterials hold promise for DNA analysis and next-generation drugs

In 1900, German physician Paul Ehrlich came up with the notion of a "magic bullet." The basic idea is to inject a patient with smart particles capable of finding, recognizing, and treating a disease. Medicine has pursued the magic bullet ever since.

19 Feb 2020

Generating genomes and encoding new abilities into artificial DNA

A new study to be presented at the American Association for the Advancement of Science (AAAS) in February 2020 will report on the generation of the world’s first artificially created bacterial genome using a digital design algorithm along with the synthesis of DNA building blocks on a large scale. This genome takes form by chemical rather than template-based synthesis. The research is published in the journal Proceedings of the National Academy of Sciences.

16 Feb 2020

PolyU develops fully automated, rapid diagnostic platform for detecting respiratory infectious diseases

The Hong Kong Polytechnic University today announced the development of the world's most comprehensive automated multiplex diagnostic system (the System) which includes a fully automated machine and a multiplex full-screening panel for the point-of-care genetic testing of respiratory infectious disease including the 2019-nCoV.

11 Feb 2020

CSU researchers uncover new information on replication of viruses

An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate.

9 Feb 2020

Developing new approaches to fight against multi-resistant pathogens

Developing fundamentally new approaches against multi-resistant germs: This is the goal of the new Bavarian research network bayresq.net which started in January 2020.

9 Feb 2020

Sperm microbiome revealed with RNA sequencing

A new study reports the first-ever detailed description of the human sperm microbiome, using newer RNA sequencing techniques that are capable of discriminating between sperm RNA and that of bacterial contamination or colonization.

2 Feb 2020

RNAssist and Rapid Labs agree on a manufacturing and supply agreement for genoPHIX and vivoPHIX

RNAssist has developed several universal biological sample stabilization, fixation and microbial inactivation reagents.

From Rapid Labs Ltd 23 Jan 2020

Scientists discover a new way to combine coding languages into single "bilingual" molecule

The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes underlying all of life.

10 Jan 2020

Scientists find way to combine two main coding languages into single 'bilingual' molecule

9 Jan 2020

Mayo Clinic researchers seek radical new approach to treat cocaine addition

In a radical new approach to treat cocaine addition, researchers at the Mayo Clinic are seeking approval for first-in-human studies of a single-dose gene therapy.

7 Jan 2020

Study shows the feasibility of using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy.

3 Jan 2020

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

Biomolecules -- carbohydrates, proteins, nucleic acids, and lipids -- form the foundation of life and are responsible for carrying out every process that occurs in our bodies.

23 Dec 2019

New paper-based test for early Lyme diagnosis

A new paper in the journal ACS Nano reports the development of an incredibly cheap and highly sensitive test to diagnose Lyme disease in its earliest stages, when it can be most easily, effectively and inexpensively treated.

18 Dec 2019

Nanosize container can slip inside cells and deliver medicines, gene therapies

Scientists at Johns Hopkins Medicine report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size -; even hefty ones attached to the gene-editing tool called CRISPR.

6 Dec 2019

New strategy could help cells get rid of disease-related debris

Tohoku University researchers have developed a strategy that could help cells get rid of disease-related debris. Further research could lead to treatments for neurodegenerative and metabolic diseases, Down syndrome, and maybe even aging-related diseases.

27 Nov 2019