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New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

Researchers investigated the role of genetics in the phenotypic association between screen time and psychiatric problems using a large population-based cohort study of preadolescents.

7 Nov 2023

Study links gut bacteria single-nucleotide polymorphisms to BMI

Researchers investigated the potential implications of single-nucleotide variations in gut-residing bacterial species (microbiome) on human health.

7 Nov 2023

The association between neighborhood deprivation, DNA methylation, and gene expression in breast tissue for Black and White women with breast cancer

Researchers investigated the association between neighborhood deprivation and alterations in DNA methylation and gene expression in breast cancer tissues of Black and White women.

7 Nov 2023

Genetic twist in gallstone disease may shield against heart attacks

Mendelian randomization suggests gallstone disease may lower heart attack risk; genetics play a key role in this protective effect.

5 Nov 2023

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Researchers investigated whether slow-wave sleep (SWS) proportions reduced as individuals aged and whether intra-individual decreases were linked to dementia risk.

1 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

AI shows promise in predicting type 2 diabetes but faces hurdles for clinical use

Researchers have conducted a comprehensive review of AI-based models for predicting type 2 diabetes, revealing their potential for individualized risk assessment and preventative care. Despite promising results, the study calls for more extensive validation and collaboration between AI and medical experts for effective clinical application.

26 Oct 2023

Fighting invisible foes: How cryptic fungal pathogens threaten human health and food security

The research paper in PLOS Pathogens delves into the challenges of diagnosing and treating cryptic fungal pathogens, which are difficult to distinguish from common fungi but equally dangerous. The study calls for more accurate diagnostic methods and a better understanding of how these fungi interact with the human immune system and microbiome for effective treatment and prevention.

25 Oct 2023

What's really in your kombucha and kefir?

Researchers have delved into the bacterial diversity of 47 different fermented foods, revealing significant variations in microbial richness and composition. The study highlights that foods like kombucha and kefirs have high microbial diversity, while plant-based yogurt alternatives and fermented vegetables show lower levels.

24 Oct 2023

Can your sleep predict depression? Insights from a genetic study

Researchers conducted a prospective study using a population-based cohort to calculate polygenic scores and understand whether suboptimal sleep durations indicated a predisposition to depression and vice versa.

24 Oct 2023

Coffee and genetics: A complex blend impacting kidney health

Researchers dive into the intricate connection between caffeine consumption and genetic predisposition, uncovering paradoxical effects on kidney function.

22 Oct 2023

Coffee consumption reduces risk of migraines, but not other neurological diseases

Researchers use Mendelian randomization to establish a causal link between coffee consumption and reduction in migraine risk.

20 Oct 2023

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Whether inflammatory bowel disease (IBD) is causally related to extracolonic cancers.

17 Oct 2023

Cracking the code: How egg consumption and genetics team up to affect heart disease risk

Egg consumption and genetic factors synergistically increase the risk of coronary artery disease, according to a large prospective study. The findings may lead to personalized dietary guidelines for those at greater genetic risk for heart disease.

16 Oct 2023

Is there an association between vitamin D deficiency and sepsis mortality?

The impact of deficient serum vitamin D levels on sepsis prognosis.

12 Oct 2023

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

Genes may be responsible for third of complex regional pain syndrome cases. But the condition is less common in men, even though they are more likely to have the 4 genetic variations implicated in heightened risk, suggesting that there may be sex specific causes, say the researchers.

10 Oct 2023

Is your DNA steering you towards a vegetarian diet?

Researchers using the UK Biobank identified genetic markers linked to strict vegetarianism, revealing potential connections between vegetarianism, lipid metabolism, and brain activity. The study highlighted genes, particularly those active in the brain and related to cholesterol movement, as influential in an individual's inclination towards a vegetarian lifestyle.

9 Oct 2023

Nucleotide News and Research

New insights into migraine etiology: the role of hepatocyte growth factor

Pharmacogenomics holds promise for personalized dementia therapies

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

Study links gut bacteria single-nucleotide polymorphisms to BMI

The association between neighborhood deprivation, DNA methylation, and gene expression in breast tissue for Black and White women with breast cancer

Genetic twist in gallstone disease may shield against heart attacks

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

How one gene shakes up our understanding of male infertility

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

AI shows promise in predicting type 2 diabetes but faces hurdles for clinical use

Fighting invisible foes: How cryptic fungal pathogens threaten human health and food security

What's really in your kombucha and kefir?

Can your sleep predict depression? Insights from a genetic study

Coffee and genetics: A complex blend impacting kidney health

Coffee consumption reduces risk of migraines, but not other neurological diseases

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Cracking the code: How egg consumption and genetics team up to affect heart disease risk

Is there an association between vitamin D deficiency and sepsis mortality?

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

Is your DNA steering you towards a vegetarian diet?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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