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New And Improved Method For Analyzing Single-Cell Gene Expression

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24 Sep 2013

Researchers develop new, improved technique for single-cell gene expression analysis

A team of researchers affiliated with Ludwig Cancer Research and the Karolinska Institutet in Sweden report in the current issue of Nature Methods a dramatically improved technique for analyzing the genes expressed within a single cell -- a capability of relevance to everything from basic research to future cancer diagn

23 Sep 2013

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

Researchers at Weill Cornell Medical College have discovered why a tiny alteration in a brain gene, found in 20 percent of the population, contributes to the risk for anxiety, depression and memory loss.

20 Sep 2013

Researchers identify likely molecular pathway that causes untreatable neurodegenerative diseases

University of Adelaide researchers have identified a likely molecular pathway that causes a group of untreatable neurodegenerative diseases, including Huntington's disease and Lou Gehrig's disease.

19 Sep 2013

Sequenom announces Certified Service Provider program for technical certification

Sequenom, Inc., a life sciences company providing innovative diagnostic testing and genetic analysis solutions, today announced a Certified Service Provider (CSP) program for the technical certification of selected laboratories offering research services using the Sequenom research-use-only MassARRAY System.

18 Sep 2013

Gene variations predict breast cancer sleep disturbance

Researchers have identified cytokine gene variations in women with breast cancer that may help to identify those at increased risk for sleep disturbance following surgery.

16 Sep 2013

NIH awards nearly $14M grants to research on how genetic factors influence susceptibility to disease

Five research teams have received new four-year awards to study the genomics of disease susceptibility in ethnically diverse populations. The projects aim to unravel the subtle variations in genetic makeup among groups - including African-Americans, Asian-Americans, Hispanics and more - that may account for differences in risks for conditions such as high blood pressure and high blood lipids, in addition to common diseases such as cancer and heart disease.

7 Sep 2013

Plasma marker inflames schizophrenia risk

Elevated plasma levels of the inflammatory molecule C-reactive protein may be a marker of an increased risk for developing schizophrenia, a study suggests.

6 Sep 2013

Bioinformatics researchers investigate functional diversity of proteins

No two human beings are the same. Although we all possess the same genes, our genetic code varies in many places. And since genes provide the blueprint for all proteins, these variants usually result in numerous differences in protein function. But what impact does this diversity have? Bioinformatics researchers at Rutgers University and the Technische Universitaet Muenchen have investigated how protein function is affected by changes at the DNA level.

6 Sep 2013

Disease Twofer: Parkin Problem Leads To Parkinson’S And Impairs Response To TB

University of California, San Francisco researchers report that a key protein associated with Parkinson's disease also plays a major role in the destruction of the bacteria that cause tuberculosis.

5 Sep 2013

Aortic stenosis doubles in patients with family history of the condition

Aortic stenosis is the most common heart valve disease in the elderly. It is associated with congenital bicuspid aortic valve and previous rheumatic heart disease, but is also often caused by calcification of a normal valve. Calcification of a normal valve may be associated with atherosclerotic changes in the portion of the aorta closest to the valve.

2 Sep 2013

Schizophrenia genetics come into focus

A study in Nature Genetics illustrates the large impact of genetic variation on risk for schizophrenia.

30 Aug 2013

Blood test provides tool essential to trials of therapies for Huntington's disease

An assay designed to measure normal and abnormal forms of the huntingtin protein - the mutated form of which causes Huntington's disease - was successful in detecting levels of the mutant protein in a large multicenter study of individuals at risk for the devastating neurological disorder.

30 Aug 2013

Life Technologies announces end-to-end sequencing solution for whole human exome CNV analysis

Life Technologies Corporation today announced the first end-to-end sequencing solution for exon-level copy number variation analysis, which combines the Ion Reporter CNV data analysis workflow, the Ion AmpliSeq Exome Kit and the Ion Proton® System.

27 Aug 2013

Two Genomic Pathways Tagged For Roles In Schizophrenia

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26 Aug 2013

Study identifies 22 locations in the human genome that cause schizophrenia

A new genome-wide association study estimates the number of different places in the human genome that are involved in schizophrenia.

26 Aug 2013

DeNovoGear software uses statistical probabilities to help identify genetic mutations

Concealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many others are associated with diseases and disease susceptibility.

26 Aug 2013

Researchers identify gene that contributes to development of acute myeloid leukemia

Researchers at the University of Chicago Medicine Comprehensive Cancer Center (UCCCC) have identified a gene that contributes to the development of acute myeloid leukemia (AML). This pivotal finding follows 40 years of University of Chicago research that has slowly unraveled the genetic basis of leukemia.

21 Aug 2013

Researchers create mouse models to advance the study of unusual deadly diseases

By directly manipulating a portion of the prion protein-coding gene, Whitehead Institute researchers have created mouse models of two neurodegenerative diseases that are fatal in humans. The highly accurate reproduction of disease pathology seen with these models should advance the study of these unusual but deadly diseases.

20 Aug 2013

Study discover two new mechanisms that govern editing in key neurodevelopmental gene

RNA editing gives organisms a way to adapt the instructions that their DNA provides for making proteins. Few people would have described RNA editing as a simple process, but a new paper in Nature Communications demonstrates the process as more complex and difficult to predict than previously assumed. The study, done in living fruit flies, discovered two new mechanisms that govern editing in a key neurodevelopmental gene.

1 Aug 2013

Nucleotide News and Research

New And Improved Method For Analyzing Single-Cell Gene Expression

Researchers develop new, improved technique for single-cell gene expression analysis

Small alteration in a brain gene contributes to risk for anxiety, depression and memory loss

Researchers identify likely molecular pathway that causes untreatable neurodegenerative diseases

Sequenom announces Certified Service Provider program for technical certification

Gene variations predict breast cancer sleep disturbance

NIH awards nearly $14M grants to research on how genetic factors influence susceptibility to disease

Plasma marker inflames schizophrenia risk

Bioinformatics researchers investigate functional diversity of proteins

Disease Twofer: Parkin Problem Leads To Parkinson’S And Impairs Response To TB

Aortic stenosis doubles in patients with family history of the condition

Schizophrenia genetics come into focus

Blood test provides tool essential to trials of therapies for Huntington's disease

Life Technologies announces end-to-end sequencing solution for whole human exome CNV analysis

Two Genomic Pathways Tagged For Roles In Schizophrenia

Study identifies 22 locations in the human genome that cause schizophrenia

DeNovoGear software uses statistical probabilities to help identify genetic mutations

Researchers identify gene that contributes to development of acute myeloid leukemia

Researchers create mouse models to advance the study of unusual deadly diseases

Study discover two new mechanisms that govern editing in key neurodevelopmental gene

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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