OCT News and Research

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Link between emotional impairment and poor cognition in children with bipolar disorder

Using functional magnetic resonance imaging, Pavuluri and her colleagues examined the brain activity of teens while they were performing certain mental tasks. The researchers scanned the brains of 10 unmedicated bipolar patients with normal mood and compared them with 10 healthy subjects of the same age and gender.

20 Oct 2005

US Congress has wasted an opportunity to tackle the rising numbers of chronically hungry people in the world

On World Food Day, Oct 16, the World Food Programme (WFP) delivered some disquieting news: the number of chronically hungry people is rising again after decades of decline. Almost 6·5 million people have died so far this year from hunger and related diseases, which claim more lives than AIDS, malaria, and tuberculosis combined.

20 Oct 2005

Neurobiologists gain new insights into brain and memory

We often make unwise choices although we should know better. Thunderstorm clouds ominously darken the horizon. We nonetheless go out without an umbrella because we are distracted and forget. But do we?

19 Oct 2005

Gamma Knife Stereotactic Radiosurgery (GKRS) is an effective treatment for trigeminal neuralgia

"This has proven to be a safe, effective treatment for trigeminal neuralgia patients, without the potential facial paralysis and long-term recovery experienced with conventional surgery," said Volker Stieber, M.D., co-director of the Gamma Knife Program at Wake Forest Baptist.

19 Oct 2005

Identification of a single chromosome region linked to specific language impairment

Researchers at the University of Toronto (U of T), Capital Health's Stollery Children's Hospital in Edmonton, Toronto's Hospital for Sick Children and their international collaborators have discovered a genetic abnormality that causes a type of language impairment in children

19 Oct 2005

Study of the effects of aripiprazole, olanzapine, quetiapine and risperidone, in elderly patients with dementia

Some newer antipsychotic medications may be associated with a small increased risk of death when used to treat elderly dementia patients, psychiatrists at Johns Hopkins warn.

18 Oct 2005

Patients with head and neck cancer may be spared the risk and expense of surgery by undergoing a CT scan

Researchers with the UF Shands Cancer Center have identified criteria doctors can use to evaluate CT scans four weeks after patients undergo initial treatment. If these criteria are met, there is a 94 percent likelihood a patient's lymph nodes are cancer free, said Stanley L. Liauw, M.D., a resident in radiation oncology.

18 Oct 2005

Brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury

A study of patients who have difficulty paying attention to the left side of their environment has provided some of the first direct evidence that brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury.

17 Oct 2005

Study of the molecular mechanism involved in the human implantation process

In spite of advances in assisted reproductive technologies, more than 6.1 million women in the United States - roughly 20 percent of all women of reproductive age - suffer from infertility.

17 Oct 2005

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

WWOX gene finding could lead to a new strategy for treating lung cancer

The research focused on a gene known as WWOX, which is lost or silenced in a large majority of lung cancers, and in cancers of the breast, ovary, prostate, bladder, esophagus and pancreas. The work was led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 Oct 2005

1G8 antibody signals prostate cancer cells to stop growing and die

Researchers at UCLA's Jonsson Cancer Center have uncovered the mechanism by which an antibody blocks the growth of prostate cancer in animal models, a discovery that could pave the way for development of a new molecularly targeted therapy.

17 Oct 2005

Curry spice appears to shut down a protein active in the spread of breast cancer

Curcumin, the main ingredient of turmeric and the compound that gives curry its mustard-yellow color, inhibits metastasis to the lungs of mice with breast cancer, report researchers at The University of Texas M. D. Anderson Cancer Center

16 Oct 2005

Discovery could help make cellular immunotherapy safer

Researchers at the University of Michigan's Comprehensive Cancer Center have discovered the secret weapon behind the most powerful form of cancer immunotherapy known to medicine.

16 Oct 2005

Discovery of agent that can suppress cancer development

In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development.

13 Oct 2005

Chromosomes in the nucleus of the cell carry the material of heredity, or genes

Abnormal cell division that yields cells with an extra set of chromosomes can initiate the development of tumors in mice, researchers at Dana-Farber Cancer Institute have shown, validating a controversial theory about cancer causation put forth by a scientific visionary nearly 100 years ago.

12 Oct 2005

Biologists uncover pivotal role of a gene called "Cut"

A DNA-binding protein, Cut interprets and transcribes the developmental signals sent through the "Notch" gene, which regulates a layer of epithelial cells as they replicate and divide. But when Cut garbles those signals the result is uncontrolled cell proliferation, sometimes with dire genetic and health consequences.

12 Oct 2005

Fijiian seaweed shows potential to kill cancer cells, bacteria and the HIV virus

Researchers have discovered 10 new molecular structures with pharmaceutical potential in a species of red seaweed that lives in the shallow coral reef along the coastline of Fiji in the south Pacific Ocean.

12 Oct 2005

Protein called CPSF73 performs a necessary step in the production of human chromosomes

The study found that a protein called CPSF73 acts like scissors to cut strands of histone messenger RNA (mRNA) in the cell nucleus. This cutting action produces the mRNA needed to create histone proteins that combine with DNA to form chromosomes.

12 Oct 2005

Novel therapies for pleural mesothelioma

Researchers at New York University School of Medicine and Wayne State University have found a molecule that reveals the early stages of pleural mesothelioma, a chest cancer caused by asbestos. The finding opens the way to a blood test for the disease, according to a new study published in the Oct. 13 issue of The New England Journal of Medicine.

12 Oct 2005

OCT News and Research

Link between emotional impairment and poor cognition in children with bipolar disorder

US Congress has wasted an opportunity to tackle the rising numbers of chronically hungry people in the world

Neurobiologists gain new insights into brain and memory

Gamma Knife Stereotactic Radiosurgery (GKRS) is an effective treatment for trigeminal neuralgia

Identification of a single chromosome region linked to specific language impairment

Study of the effects of aripiprazole, olanzapine, quetiapine and risperidone, in elderly patients with dementia

Patients with head and neck cancer may be spared the risk and expense of surgery by undergoing a CT scan

Brain injury can cause detrimental functional changes in brain regions far from the site of the actual injury

Study of the molecular mechanism involved in the human implantation process

Significant step forward in the genome era

WWOX gene finding could lead to a new strategy for treating lung cancer

1G8 antibody signals prostate cancer cells to stop growing and die

Curry spice appears to shut down a protein active in the spread of breast cancer

Discovery could help make cellular immunotherapy safer

Discovery of agent that can suppress cancer development

Chromosomes in the nucleus of the cell carry the material of heredity, or genes

Biologists uncover pivotal role of a gene called "Cut"

Fijiian seaweed shows potential to kill cancer cells, bacteria and the HIV virus

Protein called CPSF73 performs a necessary step in the production of human chromosomes

Novel therapies for pleural mesothelioma

Improving Patient Recruitment for Clinical Trial Research

Micro Products with Macro Impact; The Role of Microplate Readers in Life Sciences

Insight into Sustained-Release Drug Delivery Systems

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